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E V Rusin

Publications and source records attributed to E V Rusin.

4 recordsLinked to original sources
PubMedDate not supplied

[Lymphocyte changes in ischemic heart disease].

The paper focuses on the membrane lipid complex status and lymphocyte metabolic activity in IHD patients to elaborate new approaches toward treatment and prevention of immune disorders in the above pathology. The study was made in blood specimens from 53 coronary patients presenting with progressive unstable angina. The diagnosis was made on the basis of a complex clinical-and-laboratory and electrocardiographic evaluation. The composition of the lymphocyte membrane lipid complex and blood serum was studied with the aid of the gas chromatography techniques. Three variants were identified of change in the lipid composition of lymphocyte membranes in IHD patients having undergone the above evaluation. We consider it expediant to use criteria for the state of lymphocyte membranes in IHD patients in order that we might properly deal with issues concerning diagnosis, prognosis and selection of optimum pathogenetic therapy of the medical condition in question.

Adult↗
PubMedDate not supplied

[The role of free radical processes in the development of autosensitization in ischemic heart disease].

Derangement in freeradical processes (FRP) and lipid metabolism is known to occur in ischemic heart disease. Since autoimmune component appear to play an important role in the pathogenesis of IHD, the contributers to the article studied the state of freeradical processes in IHD patients during development of autosensibilization. A total of 42 patients with unstable angina and 8 essentially healthy subjects were examined. The blood level of FRP, antioxidant protection were determined using chemiluminometry technique. The blood serum content of free cholesterol and phospholipid fatty acid composition were evaluated by gas-liquid chromatography, the T- and B-lymphocyte functional status by fluorescent probing with acridine orange. The level of autoantibodies was determined as recommended by Boiden. The lymphocyte circulating population functional activity was found to be related to the state of FRP, antioxidant protection and the blood serum lipidic complex composition.

Antioxidants↗