Biomedical subjects
Publications and source records attributed to E V Skliannaia.
Marfan syndrome is a hereditary disease of connective tissue with predominant involvement of cardiovascular system, skeleton and eyes. Timely diagnosis and adequate management can substantially decrease mortality in this condition. The review summarizes data of clinical observations and studies of etiology, pathogenesis, diagnosis and treatment of Marfan syndrome.
The Brugada syndrome is a clinical-electrocardiographic diagnosis characterized by syncopal episodes or sudden death (caused by ventricular tachycardia and ventricular fibrillation) in patients with a structurally normal heart with a characteristic electrocardiographic pattern consisting of ST segment elevation in precordial leads (Vl-V3) and a morphology of the QRS complex resembling right bundle branch block (the latter can transiently disappear). Timely diagnosis and adequate treatment may essentially decrease mortality of this disease. In our review we have summarized results of recent studies of etiology, pathogenesis, clinical picture, diagnosis and treatment of the Brugada syndrome.
Long QT interval syndrome is a cardiac disorder associated with fatal ventricular arrhythmias (torsade de pointes and ventricular fibrillation). Timely diagnosis and adequate treatment may decrease mortality due this syndrome. The present review summarizes results of recent studies of etiology, pathogenesis, clinical picture, diagnosis and treatment of the long QT syndrome.