Biomedical subjects

E V Sotnikova

Publications and source records attributed to E V Sotnikova.

3 recordsLinked to original sources

PubMed2003

[The analysis of digestion of starches from wheat with the different amylose content in in vitro conditions].

Studied a kinetics of an enzymatic hydrolysis of wheaten starches with the different contents of an amylose in conditions in vitro for the comparative characteristic on an enzymatic resistance of new kinds of starches, perspective for possible usage them as raw by production of foodstuff for ill sugar Diabetes. According to outcomes of the conducted researches the resistance of polysaccharides depends not only on the contents of an amylose in a molecule of carbohydrates. By the factors of a resistance of starches it is possible to esteem tertiary pattern of a molecule and availability of a substratum to enzymes.

Amylose↗

PubMed2002

[Resistant starches and immune system].

Different absorbtion level is inherent capacities for natural, resistant and hydrolized starches to regulate a volume of non-hydrolyzed starches in colon. This regulates an interaction with intestinal microflora to produce the short chain fatty acids and other bio-active compounds. The T- and B-lymphocyte receptors are targets for starches to disrupt the number and density of plasma membrane receptors CD3, CD4, and CD8. All starches regulate the expression of adhesion molecules LFA-1 and ICAM-1, as well as receptor Mac-1. Maize starch increases the level of spontaneous and ceramide-dependent apoptosis in thymic and spleen cells of experimental animals.

Animals↗

PubMed1989

[Questions of tactics and choice of surgery in gastroduodenal hemorrhage].

The authors analysed 368 clinical cases with gastroduodenal hemorrhages. The changes in blood microcirculation and nonspecific immunity were studied in 62 patients. They proposed a method of complex nonoperative treatment of gastrointestinal hemorrhages, including ganglionic block, which made it possible not only to reduce the operative activity but also to achieve epithelialization of ulcers in patients with peptic ulcer. As the result of the study, a unique classification of the severity of blood loss is suggested which is based on the degree of deviation off the tests studied from the normal values. If gastroduodenal hemorrhage continues, an operation is recommended, the character of which is determined by the patient's age, the severity of blood loss, and the source of bleeding and its localization.

Duodenal Ulcer↗