Biomedical subjects

E V Stel'mashuk

Publications and source records attributed to E V Stel'mashuk.

8 recordsLinked to original sources

PubMed2001

Bifonazole modulates death of cultured cerebellar granular cells induced by glutamate and oxygen-glucose deprivation.

Treatment of cultured rat cerebellar granular cells with calmodulin antagonist bifonazole (10 mM) during oxygen-glucose deprivation or exposure to glutamate (75 mM) prevented neuronal death. However, addition of bifonazole after glutamate treatment promoted neuronal death. Calmodulin antagonists trifluoperazine and thioridazine had no protective effects, while thioridazine even potentiated the toxic effect of glutamate.

Animals↗

PubMed2000

[Effect of the isoosmotic solution with decreased sodium level on mitochondria of cultured granule cells from the cerebellum].

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2-Amino-5-phosphonovalerate↗

PubMed2000

Neuroprotective properties of nootropic dipeptide GVS-111 in in vitro oxygen-glucose deprivation, glutamate toxicity and oxidative stress.

Argon anoxia and glucose deprivation were used for modeling of ischemic damage in the cultures of cerebellar granule cells. Protective effect of peptide piracetam analogue GVS-111 was demonstrated. GVS-111 prevented neurodegeneration induced by glutamate and oxidative stress. In contrast to GVS-111, piracetam did not attenuate neurocytotoxic effect of glutamate.

2-Amino-5-phosphonovalerate↗

PubMed1997