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E V Vikhrov

Publications and source records attributed to E V Vikhrov.

9 recordsLinked to original sources
PubMed1989

[Intensification of gas exchange in high-frequency artificial ventilation].

Jet high-frequency artificial ventilation produces oscillations of some parts of the chest wall, which in its turn transmits oscillations to the lung parenchyma. It results in the mix-up of the gas in the alveolar space, which leads to the increase in the gradient of oxygen concentration on the alveolar membranes, thus, augmenting oxygen saturation of the blood. The effect is the same when oscillation artificial ventilation is performed, owing to the provocation of the oscillations amplified by the resonance in the natural acoustic circuit, formed by the adjacent parts of the chest and lung parenchyma. Derangement of the exudative adhesion to the bronchi epithelial tissue intensifies gas exchange, when the oscillations are generated in the lungs. It facilitates the removal of the exudate and lets the air into the previously obstructed parts of the lungs. Clinical studies confirm the effect of the increase in the blood oxygenation (by average 20%) at the feeding air column by pneumatic oscillations in the range of 65 Hz, when traditional artificial ventilation is performed.

Acute Disease↗
PubMedDate not supplied

[A comparative evaluation of the efficacy of the traditional combination of high-frequency and intermittent high-frequency artificial ventilation of the lungs in patients with parenchymatous acute respiratory insufficiency].

Conventional controlled lung ventilation (CLV) with positive end expiratory pressure (PEEP) (Con CLV), combined high-frequency CLV (Com HF CLV) and intermittent high-frequency CLV with PEEP (Int HF CLV) have been performed in 43 patients with parenchymatous acute respiratory failure (ARF). It has been established that Int HF CLV significantly increases PaO2 in patients with focal damages of the lung parenchyma and effective compliance (Ceff) > 0.033 l/cm H2O. Com HF CLV increases significantly PaO2 and lung compliance in patients with disseminated lung damages and Ceff < 0.030 l/cm H2O and has marked consequences. Different efficacy of various types of HF CLV under study may be to some extent accounted for by different intraalveolar maximum pressure, which (as it has been shown on the lung model) is higher in Com HF CLV and lower in Con CLV and Int HF CLV.

Acute Disease↗