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Biomedical subjects

E V van Hall

Publications and source records attributed to E V van Hall.

At least 19 recordsLinked to original sources
PubMed1985

Adhesion formation after tubal surgery: results of the eighth-day laparoscopy in 188 patients.

First-look laparoscopy (FL) on the eighth day after salpingostomy, fimbrioplasty, or adhesiolysis was performed in 188 patients. Behavior of postoperative adhesions and the occurrence of pregnancy after tubal surgery were compared with a similar group of 127 patients in whom no FL was performed. In greater than 50% of the cases (104/188), adhesions were found on the eighth postoperative day around both adnexa or the only remaining adnexum. Adhesions were mainly located between the ampulla and the ovary and between the ovary and the lateral pelvic wall or broad ligament. More than half of the adhesions that were separated at FL did not recur. It was concluded that FL significantly diminished the occurrence of permanent pelvic adhesions. The incidence of ectopic pregnancy after salpingostomy was significantly lower when FL was performed. FL on the eighth postoperative day can be regarded as a well-accepted procedure with few complications.

Adnexal Diseases↗
PubMed1985

Placental-site trophoblastic tumor: diagnosis, treatment, and biological behavior.

The clinical history of a patient with a placental-site trophoblastic tumor is presented. The diagnostic and therapeutic value of dilatation and curettage, the human chorionic gonadotropin titer, hysteroscopy, laparoscopy, chemotherapy, and hysterectomy is discussed, as well as the possibility of metastatic disease. In this patient there was radiological evidence of pulmonary metastasis with apparent spontaneous regression. A proposal is made to change the name of this disease to gestational trophoblastic neoplasia of low potential malignancy.

Adult↗
PubMed1979

[Tubal surgery].

Explore the source record for details and available documents.

Appendicitis↗
PubMed1979

The "treatment" of unexplained infertility with danazol.

In order to investigate the possible stimulating effect of danazol on fertility, a randomized clinical trial was performed on 40 women with unexplained infertility. Of these 40 women, 21 received 200 mg of danazol daily for 100 days and 19 received a placebo treatment during the same period. Serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin, estrone, estradiol, progesterone, and testosterone were followed before, during, and after treatment. Danazol administration induced anovulation in all women, with prompt resumption of normal ovulatory function after discontinuation of the drug. No influence was seen on serum LH, FSH, and testosterone levels, but serum estrone, estradiol, and progesterone levels decreased significantly during treatment. Serum prolactin levels also decreased, but not significantly. No pregnancies occurred in the placebo group during a 6-month follow-up period. In the danazol group, five pregnancies occurred, of which two were ectopic and three went to term. The difference in pregnancy rate between both groups was statistically significant (P less than 0.05).

Adult↗
PubMed1979

Treatment of unexplained infertility with danazol.

In order to investigate the possible stimulatory effect of danazol on fertility, a randomized clinical trial was performed on 40 women with unexplained infertility. Twenty-one women received 200 mg danazol daily for 100 days and 19 women received a placebo for the same period. No pregnancies occurred in the placebo group during a 6 month follow-up period. In the danazol group, 5 pregnancies occurred of which 1 were ectopic and 3 went to term.

Clinical Trials as Topic↗
PubMed1978

Prevention of peritoneal adhesions by the combined use of spongostan and 32% dextran 70: an experimental study in pigs.

Twenty female pigs underwent laparotomy during which transection of both uterine horns and wedge resection of both ovaries were performed with a standard technique. Following the injuries a mixture of Spongostan and 32% dextran 70 was applied only to the lesions on the right side. Three weeks after surgery another laparotomy was performed and the degree of adhesion formation was recorded. A marked reduction in degree and extent of adhesions was observed on the treated side as compared with the control side. The possible advantages of a compound that can be applied locally and has hemostatic properties as well are discussed.

Administration, Topical↗
PubMed1977

A radioligand receptorassay for serum HCG.

A radioligand receptorassay system is described for the measurement of human choriogonadotrophin (HCG) in serum, using 600-1600 X g fractions of homogenates of superovulating rat ovaries. The method is specific for HCG and lutrophin (LH), with a detection limit of 3.5 mIU HCG. The values obtained in the dilutions of pregnancy sera paralleled the standard curve up to 20 microliter, and no non-specific effects were found with this amount of serum. The potency ratio R/I, measured in normal pregnancy sera by radioligand receptorassay and radioimmunoassay, varied between 1.1 and 3.2. No relationship was found between the stage of pregnancy and the R/I ratio.

Chorionic Gonadotropin↗
PubMed1976

Serum levels of unconjugated aetiocholanolone androstenedione, testosterone, dehydroepiandrosterone, aldosterone, progesterone and oestrogens during the normal menstrual cycle.

The results of daily determination of the levels of gonadotrophins, oestradiol, oestrone, progesterone, aldosterone, dehydroepiandrosterone, androstenedione, testosterone, and aetiocholanolone in the serum of 6 normal, ovulating women are reported and discussed. A pre-ovulatory aldosterone peak and rising values in the luteal phase of the cycle were found. Androstenedione, testosterone, and aetiocholanolone levels were significantly elevated from 3 days before until 3 days after ovulation. Since the mean androstenedione/aetiocholanolone ratio in the individual cycles in this period was similar to the ratio found during the rest of the cycle, we think it unlikely that aetiocholanolone is produced by the ovaries. No correlation was found between the aetiocholanolone patterns and the basal body temperature. In a case of conception followed for 20 days after ovulation, the steroid patterns remained unchanged until the presumed day of implantation, after which the aldosterone, androstenedione, testosterone, and aetiocholanolone levels started to rise. The mean androstenedione/aetiocholanolone ratio during the 10 days after implantation did not differ from the values obtained in the foregoing periods, so direct aetiocholanolone production by the ovaries after implantation seems unlikely.

Aldosterone↗