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Biomedical subjects

E Vigl

Publications and source records attributed to E Vigl.

5 recordsLinked to original sources

Malignant blue nevus. Report of four new cases and review of the literature.

Malignant blue nevus is a rare melanotic tumor of the skin arising from a pre-existing blue nevus. To date only few cases have been reported. The diagnosis of malignant blue nevus is frequently difficult. Generally accepted criteria do exist, but their application may be controversial. The present paper reports four new cases of malignant blue nevus with follow-up of 3-5 years. Our present data, along with those of the literature, suggest that malignant blue nevus may be more aggressive than generally thought.

Adult↗

[Multiple glomus tumors].

Two patients with disseminated glomus tumors (glomangiomas) are reported. Histologically, the angiomatous from typical of multiple glomus tumors was found. Th glomus tumors are related to the arterio-venous anastomoses (organ of Hoyer-Grosser). The most important histological variants are the epithelioid and the angiomatous type. Possibly, the former is related to the arterial segment, the latter to the venous segment of the normal arterio-venous anastomoses. The histological identification of glomus cells is diagnostic. The nature of these cells has been under discussion since Masson's time. Ultrastructurally, they have been clearly identified as modified smooth muscles cells. Electron-microscopy can be helpful in the differentiation of glomus tumors from hemangiopericytomas which may sometimes be difficult histologically.

Adult↗

[Trichorrhexis congenita. Scanning electron microscopic studies on a congenital disorder of hair growth].

1. A congenital disturbance of hair growth belonging to the "trichorrhexis nodosa" group is described. Clinically, abnormal hair fragility since birth was the leading symptom. There was no detectable amino-aciduria. 2. The scanning electron microscope (SEM) reveals localized alterations of the hair shafts. These are irregularities of the cuticular pattern, partial fractures of the cortical filament bundles, and complete fractures with broom-like splintering of the hair ends. 3. There is no generally accepted definition of the symptom or the disease of "trichorrhexis nodosa". Further SEM analysis and collection of such hair anomalies is proposed. As in the case described here no "nodes" of the hair shaft were observed, it is presented as "trichorrhexis conginita".

Child, Preschool↗