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Biomedical subjects

E Voegeli

Publications and source records attributed to E Voegeli.

At least 19 recordsLinked to original sources
PubMed2006

[Histiocytic sarcoma in the Swiss population of Bernese mountain dogs: a retrospective study of its genetic predisposition].

A retrospective study to evaluate the genetic predisposition for histiocytic sarcoma in the Swiss population of purebred Bernese mountain dogs identified 51 histologically confirmed cases between 1997 and 2003. Segregation analysis using five major genetic modes was used to evaluate the 51 cases. The general mode yielded the best results suggesting a genetic predisposition for histiocystic sarcoma in this breed. The disease was found in all families analyzed, therefore elimination of the disease through seletive breeding of certain family lines is not possible.

Animals↗
PubMed1997

[ROC comparison of visualization of hand fractures using digital and conventional techniques].

PURPOSE: To compare the accuracy of digital luminescence radiography (DLR) and conventional film-screen radiography (FSR) in diagnosing fractures. MATERIAL AND METHOD: Both conventional and digital radiographs were acquired from a consecutive series of 57 patients with suspected wrist or hand fractures. The digital images were obtained with a 30% dose reduction. A ROC-analysis (receiver-operating characteristics) was performed. RESULTS: The area under the curve was 0.89 for conventional FSR, 0.93 for DLR, "gray scale" and 0.94 for DLR, "edge enhanced". CONCLUSIONS: Although its spatial resolution is lower, DLR provided better results than conventional FSR, when contrast processing algorithms were optimised for the specific clinical question. The edge-enhanced version was superior to the non-edge enhanced version. The reason for this seems to be the higher contrast resolution of DLR compared to FSR.

Adolescent↗
PubMed1996

Evaluation of the clinical safety and efficacy of iobitridol (Xenetix) in intravenous urography.

The aim of this study is to report on the clinical safety and diagnostic efficacy of iobitridol (Xenetix) in intravenous urography compared to iohexol (Omnipaque) or iopamidol (Iopamiro). A total of 120 patients underwent intravenous urography (i.v.u.); 60 received Xenetix and 60 either Omnipaque (30 patients) or Iopamiro (30 patients) according to the center where they were treated. Clinical safety was assessed by the reporting of adverse events and diagnostic efficacy was evaluated. Warmth sensation was the most commonly reported adverse event. Two cases of nausea and vomiting were reported. Concerning diagnostic efficacy, 72-74% of the i.v.u. examinations were rated good or excellent by the physician. These studies confirm that Xenetix is a suitable contrast agent for i.v.u.

Contrast Media↗
PubMed1992

[Evaluation of clinical tolerability and diagnostic efficacy of ioversol 350 in UIV. A randomized double-blind study of ioversol 350 versus iohexol 350].

The authors evaluated the clinical safety and the efficacy of ioversol compared to the reference contrast medium iohexol, during IVP. The clinical safety has been evaluated by the occurrence of side-effects. The efficacy was appreciated in terms of insufficient, medium, good or excellent. No side-effect was recorded for both contrast media. There was no difference in opacification quality and efficacy between ioversol and iohexol. The authors conclude that ioversol is a safe and effective contrast medium which can be, therefore, particularly recommended for urographic examinations of high risk patients.

Double-Blind Method↗
PubMed1985

[Critical remarks on computer tomography of the chest in the staging of bronchial cancer].

The planning of treatment in patients with non-oat cell carcinoma of the lung requires an extensive diagnostic work-up. As far as TN-staging is concerned, the role of CT is controversial. On the basis of 25 operated and histologically proven cases of non-oat cell cancer of the lung, the results of both CT and conventional radiography are critically evaluated. In the present study CT is found to be more sensitive but not more specific than conventional radiography in detecting pleural invasion and regional, especially mediastinal, lymphnode metastases. These results are in accordance with those of others. Since both modalities follow the same diagnostic criteria (lymphnode size, contact to pleura), an increase in sensitivity is intimately related to a corresponding loss of specificity. The relatively high sensitivity of CT on the one hand, and the relatively high specificity of conventional radiography on the other hand, suggest the following procedure: if conventional radiography is definitely positive, additional CT can be omitted. If CT proves negative as well, the presence of mediastinal metastases or pleural invasion is very unlikely. Positive findings on CT, however, need histologic verification.

Adult↗
PubMed1985

A diagnostic approach to lytic lesions of the mandible.

Fifty seven patients with histologically proven cyst-like lesions of the mandible are reviewed. The importance of combining radiographic with scintigraphic imaging is stressed. These two imaging modalities are complementary in demonstrating both the biological activity and the extent of the lesion. In osteomyelitis the bone scan, which is more sensitive than the radiograph, is also the method of choice in assessing the result of treatment.

Adolescent↗
PubMed1985

[From the x-ray department to the institute for imaging diagnosis].

The increasing sophistication of diagnostic radiology has led to rising emphasis on modality-related training and practice in radiological subspecialties. To accomplish both optimal patient management and a rational, cost-effective analysis of imaging procedures, a comprehensive approach to modern radiology is needed rather than a technology-related attitude. The imaging department, where the various imaging data are synthesized and correlation by a general practitioner of radiology, as opposed to the subspecialty radiologist, is the most suitable solution. The principles of management and the layout of such a center are described by the authors.

Efficiency↗
PubMed1984

[Sonography and computed tomography in postoperative abdominal abscesses].

After abdominal surgery there is a 1.3% incidence of early relaparatomy. Peritonitis is the most frequent underlying disease, with a mortality rate of 58%, if treatment is attempted by explorative surgery. On the basis of 24 postoperative abdominal abscesses out of 1023 laparatomies during an 18-month period sonography and CT scanning proved to be most accurate in detecting postoperative inflammatory lesions despite the lack of specific criteria. Thus, both methods reduce the risks of relaparatomy by facilitating the surgical approach on the one hand, and on the other hand, they alternatively provide the possibility of percutaneous puncture or drainage.

Abdomen↗
PubMed1983

[Conventional radiology and computed tomography in facial fractures].

The possibilities and limitations of conventional radiography and CT in detecting maxillo-facial fractures are shown both experimentally and in a clinical setting. In 36 patients examined by both methods after maxillo-facial trauma, CT and conventional radiography (including pluridirectional tomography) proved to be equal in detecting fractures of the orbital roof, the anterior wall of the frontal sinus, the nasal bone and the pterygoid process. CT is inferior to conventional radiography in fracture of the orbital floor, the frontal base of the skull, the hard plate and the zygomatic arch. CT is superior to conventional radiography in fractures of the medial and lateral wall of the orbit, the posterior wall of the frontal sinus, the posterior, medial and anterior wall of the maxillary sinus as well as the zygomatic bone.

Facial Bones↗
PubMed1980

[X-ray diagnosis of pancreatic carcinoma].

On the basis of 27 periampullary carcinomas and 3 carcinomas of the body and tail of the pancreas observed in the last 18 months, the authors summarize their experience with various invasive and noninvasive radiologic techniques and express their views on the diagnostic approach to these tumors.

Cholangiography↗
PubMed1980

[The value and limitations of sonography and angiography in the investigation of renal masses (author's transl)].

The diagnostic value of ultrasound and angiography is compared in 80 renal masses. Whereas the overall accuracy is approximately the same (95%), there are inherent limitations to both methods. As to sonography, the limiting factors consist of size, complex echopattern and lack of tissue distinction. Angiography, on the other hand, has its limitations in hypovascular tumors as well as in benign lesions simulating malignancy (abscess, hamartoma).

Adolescent↗