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Biomedical subjects

E W Adams

Publications and source records attributed to E W Adams.

13 recordsLinked to original sources
PubMed2000

Investigation of lung disease in preterm infants using magnetic resonance imaging.

Many preterm infants require ongoing respiratory support despite treatment with exogenous surfactant. The reasons for this are unclear, but may involve one or a combination of changes in water content or distribution within the lung. Detailed three-dimensional information with the potential to provide quantitation of water content may help to investigate this further. We aimed to determine if magnetic resonance (MR) imaging could be developed to study lung disease in preterm infants. Appropriate MR sequences and procedures were defined and we found that T1 and proton density weighted images could be successfully acquired. The images contained three-dimensional information that could not be obtained using chest radiograph. MR imaging may be a useful method for studying the pathology of respiratory distress syndrome and chronic lung disease in preterm infants.

Humans↗
PubMed1987

The distribution of C-bands in canine transmissible venereal tumor cells.

Colchicine-arrested metaphase preparations, derived from canine transmissible venereal tumor (TVT) cells grown in culture, were characterized based on the occurrence and distribution of constitutive heterochromatin. Analysis of the data with regard to the distribution of C-bands in the pericentric, interstitial and telomeric segments revealed a nonrandom distribution along the arms of many chromosomes with the bulk of the bands occurring in the centromeric region. The frequency of C-banded regions differed from those reported for normal dog cells and both primary and transplanted tumors. These results suggest that similar nondifferentially-stained TVT karyotypes do not necessarily exhibit identical distribution of constitutive heterochromatin.

Animals↗
PubMed1981

Cytogenetic observations on the canine venereal tumor in long-term culture.

Cytogenetic observations are reported on five canine venereal tumor tissue culture cell lines maintained over periods of 13 to 30 months. In all instances, a karyotype was observed that is strikingly similar to those reported elsewhere for spontaneous or transplanted venereal tumors. The modal number in all lines was close to 59, containing 17 to 19 abnormal metacentric chromosomes. Three of the metacentric chromosomes were identified as markers. Assays for oncogenic properties were undertake in heterologous and homologous hosts. Attempts to induce tumor formation in homologous hosts using the cultured venereal tumor cell were uniformly unsuccessful.

Animals↗
PubMed1979

Comparative approach to health maintenance: how will it work?

A prototype for the implementation of a comprehensive health maintenance program is described in which the expertise of veterinary medicine is brought to bear on preventive medicine and on special generic environmental disease factors as they impact on human health. For the sake of organization and the ease of presentation, certain specific activities have been divided into two overlapping categories: environmental health and health education. The implementation of a comprehensive health care delivery system will become a reality only when the full array of health resources is matched with health needs. It cannot be overemphasized that the delivery of health care services is not exclusively within the purview of any one profession; rather, interdependence and sharing of responsibilities and activities in a team approach are characteristics of the human health system.

Alabama↗
PubMed1979

Induction of acid-stable canine interferon in vivo and in vitro.

Dogs were able to produce only small quantities of circulating interferon after intraperitonal injection of Newcastle disease virus or polyinosinic-polycytidylic acid. Similarly, canine cell cultures produced very low concentrations of interferon in response to Newcastle disease virus or polyinosinic-polycytidylic acid and no detectable concentrations of interferon in response to pyran copolymer or tilorone hydrochloride. The antiviral substance met the physiochemical characteristics classically associated with interferon.

Animals↗