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Biomedical subjects

E W Akins

Publications and source records attributed to E W Akins.

At least 19 recordsLinked to original sources
PubMed1992

Use of transesophageal echocardiography to visualize an anomalous right coronary artery arising from the left main coronary artery (single coronary artery).

This case report demonstrates a role for transesophageal echocardiography in defining the course of anomalous coronary arteries. Origin of the right coronary artery (RCA) from the left main (LM) (single coronary artery) is an exceedingly rare congenital anomaly. It is not always benign and may result in myocardial infarction. This may be due to compression between the aorta and the pulmonary artery. Transesophageal echocardiography offers a low-risk, noninvasive means of imaging the proximal coronary arteries. In the majority of patients, the proximal segments of the three major coronaries can be clearly visualized. With the addition of color flow, it is possible to visualize flow in most patients. Proximal obstructive lesions can be seen in some patients although sensitivity thus far seems low.

Blood Flow Velocity↗
PubMed1991

Carbon dioxide as an angioscopic medium. Comparison to various methods of saline delivery.

The limitations of angiography, when it is used as the sole method of vascular assessment, are increasingly apparent as vascular intervention becomes more sophisticated. Angioscopy could be an adjunctive diagnostic modality by differentiating among thrombus, dissection, and atheroma, and by monitoring the response to therapy. However, angioscopy requires a blood-free field for adequate visibility, and this may be difficult to obtain. The feasibility of carbon dioxide (CO2) and various saline delivery methods for clarifying the viewing field for percutaneous angioscopy was investigated. Angioscopy of femoral and iliac arteries on nine dogs was performed. Saline was infused by hand injection, pressure bag infusion, or mechanical power injection, and CO2 gas was injected using a special gas injector. The clarity of the viewing field was graded for each medium and method. Excellent quality antegrade femoral angioscopy was obtained with CO2. The superiority of CO2 injection in comparison with power-injected saline approached statistical significance (P = .06). Power-injected CO2 and power saline were superior to hand-injected or pressure bag-injected saline for maintaining sufficient visibility. Retrograde iliac angioscopy was possible without inflow occlusion, but required high flow rates (only possible with power-injected saline or CO2). CO2 injected under controlled circumstances holds promise as a medium to improve angioscopic visibility.

Angiography↗
PubMed1991

Perivalvular pseudoaneurysm complicating bacterial endocarditis: MR detection in five cases.

Bacterial endocarditis usually affects the valve leaflets, but erosion into the valve anulus and adjacent myocardium may form a myocardial abscess. Perivalvular abscesses can drain into the ventricles or aorta, forming a life-threatening pseudoaneurysm. We reviewed our experience with cardiac MR imaging of this disorder. Fourteen patients with complicated bacterial endocarditis underwent ECG-gated spin-echo cardiac MR imaging in addition to conventional duplex two-dimensional echocardiography (2-D echo). Angiography was performed in seven patients, six of whom underwent surgery for valve replacement. MR imaging detected the pseudoaneurysms in all five of the surgically proved cases, while 2-D echo detected only three. Clinical follow-up suggested there were no false-negative examinations, but no autopsy data were available for confirmation. Postoperative MR imaging studies were conducted in three patients, revealing two recurrent pseudoaneurysms and one thrombosed aneurysm. Cardiac MR imaging provides useful pre- and postoperative information in patients with perivalvular pseudoaneurysms due to endocarditis.

Aneurysm, Infected↗
PubMed1990

Guide-wire reinforcement and lengthening with coaxial locking guide wires: the crimping technique.

The authors developed a technique to increase the size of a guide wire and permit single-step placement of catheters and large sheath systems over previously inserted small-caliber guide wires. The technique involves compression of metal cannula against a smaller in-dwelling wire or inner cannula. It has been used successfully during laser-assisted balloon angioplasty and percutaneous nephrolithotomy.

Angiography↗
PubMed1990

A solution to the problem of high-flow jets from miniature angiographic catheters.

In this study we evaluated methods for reducing high-flow jets from 5-French catheters that occur when injection pressures approach catheter tolerance (1000 psi [6.9 MPa]). This "jet effect" has been responsible for subintimal extravasation of contrast material in patients. We designed a physical model that accurately measures flow rates through the end hole and each side hole of 5-French high-flow catheters under simulated physiologic arterial pressure. When a standard catheter commonly used for injection of contrast material was studied, flow of contrast material was 34% through the end hole and 31% through the distal side-hole pair at high injection pressures (1000 psi). We examined the effect of altering the size and configuration of catheter side holes and end hole in an effort to create an improved flow profile, and thus a safer angiographic catheter. End-hole flow rate was reduced by 73% to 9% of total flow by tapering the 5-French catheter to 0.018 in. (0.046 cm) and by using smaller 0.015-in. (0.038-cm) side holes for even flow distribution. The high-flow jets present with standard high-flow 5-French catheters do not occur when flow-restrictive end holes and side holes are used. A uniform flow profile can be obtained without sacrificing delivery of contrast material through small catheters.

Angiography↗
PubMed1989

Miniaturization of catheter systems for angiography.

Miniature techniques offer many advantages for performance of routine angiography, as well as invasive vascular procedures. On the basis of the authors' experience with over 16,000 diagnostic and interventional procedures, this report describes the equipment and methods used for miniangiography. Development of sturdy, high-flow 3-5-F catheters and 0.014-0.018-inch guide wires, combined with the use of small needle puncture techniques, has improved the safety of angiography and intervention such that outpatient procedures are now routine. Miniature catheter systems are now preferable to larger catheter systems in most instances.

Angiography↗
PubMed1989

Improved detection of healed myocardial infarction by Fourier amplitude and phase imaging in two projections: validation with MRI.

Biplane Fourier amplitude and phase images from radionuclide ventriculograms were analyzed for the presence of regional wall motion abnormalities in 25 patients who had a total of 33 healed myocardial infarctions (nonviable scar tissue) documented by contrast ventriculography and ECG. This indirect evidence was validated by MRI, which permits direct visualization of healed myocardial infarction. The use of amplitude and phase images in both projections resulted in the detection of more healed myocardial infarctions (91%) than did the use of conventional radionuclide ventriculography with left anterior oblique images alone (67%), because inferior wall infarcts are more readily visualized in the left posterior oblique projection.

Adult↗
PubMed1989

New high-flow "cloud" catheter for safer delivery of contrast material.

The authors describe a new angiographic catheter, which delivers equal flow rates through the side holes and reduced flow through the end hole compared with conventional catheters. Computer analysis of catheter-flow models revealed that placement of larger side holes proximally and smaller side holes distally produces more uniform flow rates out of the holes. This decreases the risk of potentially hazardous delivery of high-pressure jets of contrast material from the end hole. The flow pattern is so uniform that it resembles a cloud of contrast material on injection. This catheter design is particularly applicable for 3-5-F catheters, which require high-pressure injections. Clinical testing in 50 cases revealed no extravasations or unintentional selective injections with use of this catheter.

Angiography↗