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Biomedical subjects

E W Fletcher

Publications and source records attributed to E W Fletcher.

At least 55 records · Page 3Linked to original sources
PubMed1975

Urinary tract in schoolgirls with covert bacteriuria.

During screening of 16,800 primary schoolgirls, aged 4-12 years, in Cardiff and Oxford, significant bacteriuria was found in 294 (1-7%). Intravenous urography and micturating cystography were performed in 246 of these girls. The urinary tract was abnormal in 47%. Pyelonephritis with or without vesicoureteric reflux was present in 26% and reflux without renal abnormality in a further 16%. The prevalence of pyelonephritis and reflux was independent of age. With few exeptions kidneys without pyelonephritic scars appeared to be normal in size, even when ureteric reflux was present.

Bacteriuria↗
PubMed1975

Evaluation of a method for quantifying the angiographic severity of major pulmonary embolism.

A method has been evaluated for the quantification of the angiographic severity of pulmonary embolism. There was close agreement between observers especially in the more severely affected cases. The method has been shown to be sensitive enough to demonstrate highly significant differences between treatment regimens and to assist in the selection of treatment at the outset.

Angiography↗
PubMed1975

The findings reported in patients undergoing excretory urography for recurrent urinary tract infection.

There was little difference between the proportion of lesions found by excretion urography in patients with recurrent urinary tract infections referred by general practitioners or hospital staff, or between Horton General Hospital which is a district general hospital, and the United Oxford Hospitals, which is a teaching group. Many patients with urinary tract infections may be saved an unnecessary visit to the hospital consultant if this is first investigated by the general practitioner.About one fifth of all patients had significant lesions shown by excretory urography which suggests that the investigation is worthwhile in patients with recurrent urinary tract infections.

Adolescent↗
PubMed1974

Comparison by controlled clinical trial of streptokinase and heparin in treatment of life-threatening pulmonay embolism.

Treatment with heparin or streptokinase was allocated randomly to 30 patients with life-threatening pulmonary embolism verified by angiography. Treatment was given for 72 hours and pulmonary angiography was repeated. There was significantly greater (P < 0.001) evidence of thrombolysis in those patients treated with streptokinase compared with those treated with heparin. The reduction of systolic and mean pulmonary arterial pressures was also significantly greater (P < 0.05 and P < 0.02 respectively) in the streptokinase group.Seven patients failed to complete 72 hours of the trial treatment: five successfully underwent pulmonary embolectomy. Six of these "failures" had initial pulmonary angiographic scores of 24 or more and systemic systolic blood pressure recordings of 100 mm Hg or less. Patients with these features should probably be considered for pulmonary embolectomy as the initial treatment.A febrile reaction commonly occurred in the streptokinase group; otherwise side effects were no more common than in the heparin group.

Angiography↗