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Biomedical subjects

E W Purnell

Publications and source records attributed to E W Purnell.

18 recordsLinked to original sources
PubMed1994

Retinal necrosis in X-linked lymphoproliferative disease.

BACKGROUND: X-linked lymphoproliferative disease is a hereditary disease that renders the males susceptible to fatal infectious mononucleosis, aplastic anemia, malignant lymphoma, and hypogammaglobulinemia after infection by the Epstein-Barr virus. METHODS: The authors examined the clinical and pathologic findings in an 8-year-old boy with bilateral retinal necrosis who died with aplastic anemia as a complication of X-linked lymphoproliferative disease. RESULTS: Results of histopathologic examination of the eyes disclosed retinal necrosis, and examination using the polymerase chain reaction technique showed Epstein-Barr virus genomic DNA in the left eye. CONCLUSION: Retinal necrosis may be part of the expanding spectrum of X-linked lymphoproliferative disease. It is unknown if the retinal necrosis is due directly to Epstein-Barr virus infection or a host inflammatory response.

Child↗
PubMed1988

Subretinal neovascularization after focal argon laser for diabetic macular edema.

The authors reviewed four cases of iatrogenic subretinal neovascularization after focal argon green photocoagulation for clinically significant diabetic macular edema. An inappropriate combination of small spot size with a high-power setting is the common feature in each case of iatrogenic subretinal neovascularization. Close follow-up with fluorescein angiography is used to identify iatrogenic subretinal neovascularization at an early, treatable stage. All four patients responded favorably to laser photocoagulation of the subretinal neovascular membrane.

Choroid↗
PubMed1978

Subretinal neovascularization following rubella retinopathy.

A 17-year-old girl and an 11-year-old girl with rubella retinopathy had decreased vision in one eye secondary to subretinal neovascularization and hemorrhage. In both cases a disciform scar with permanent decrease in central vision resulted.

Adolescent↗
PubMed1978

Relative frequency of ultrasound diagnoses in patients referred for ophthalmic ultrasound.

An ultrasound diagnostic coding system was developed that permitted entry of diagnoses into a programmable calculator, thus permitting rapid information retrieval of patients with a specific diagnosis or diagnoses as well as the number of patients with a specific diagnosis. Cataract, vitreous opacity, trauma, choroidal disease, and retinal detachment were the most common diagnoses made. Only 7.2% of the patients had a normal ultrasound, indicating that ultrasound examination is a test probably underutilized by ophthalmologists.

Computers↗
PubMed1975

Clinical spectra-color ultrasonography.

Results of preliminary clinical trials of spectra-color ultrasonography are presented. The instrumentation is calibrated so that normal ocular tissues produce a near-white display. Scans of eyes with various diseases differ from the scans of normal eyes, indicating a variation in frequency responses.

Calibration↗
PubMed1975

Bilateral microphthalmos without microcornea associated with unusual papillomacular retinal folds and high hyperopia.

A 23-year-old man had bilateral microphthalmos without microcornea. The eyes measured about 15 mm in length by ultrasound while the corneas were 11 mm in diameter. A distinctive, elevated, funnel-shaped retinal fold stretching between the disk and the macula was present bilaterally. Other unusual aspects were the deep anterior chambers and uncompromised chamber angles. This combination of anomalies is believed to be the result of a failure of growth of the posterior outer coats of the eye. These were of insufficient size to accommodate the excess sensory retina which folded to conform to its outer structural shell. Other cases of high hyperopia may in some instances be cases of microphthalmos, unrecognized because of normal-sized corneas.

Adult↗