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Biomedical subjects

E W Radue

Publications and source records attributed to E W Radue.

45 records · Page 3Linked to original sources
PubMed1978

Xenon enhancement in tumours and infarcts.

Computed topography (CT) before and during xenon enhancement and computer subtraction has been performed in 11 patients with intracerebral tumours and 7 with ischaemic lesions. The amount of xenon uptake was expressed where possible as a percentage of that in the corresponding region of the contralateral apparently normal hemisphere. The amount of xenon uptake did not appear to be specific for any particular tumour histology. The margins of tumours were better defined during enhancement, but not to a degree which affected management; large cysts did not enhance and were well demonstrated. Cavities due to mature infarcts did not enhance and the central parts of most large recent infarcts showed markedly diminished enhancement. In recent infarcts delayed xenon uptake at the periphery and sometimes throughout the lesion reflects diminished perfusion of potentially viable tissue. One patient with an ischaemic parietal lesion in which xenon uptake was normal made a complete clinical recovery.

Brain↗
PubMed1978

Comparison of computerised tomography with other neuroradiological methods. A plea for a different kind of analysis.

Two different types of retrospective study of the value of CT have been contrasted. In one, the patients were chosen because of the way they presented (with posterior fossa signs of symptoms) or because they were found to have posterior fossa disease; in the other, all were reported as having, or found to have, gliomas or metastases. The first type of study provides a better basis for evaluation of neuroradiological procedures.

Brain Diseases↗
PubMed1978

Diagnosis of subdural haematoma by computed axial tomography: use of xenon inhalation for contrast enhancement.

A subdural haematoma is described in which a definite computed tomographic (CT) scan diagnosis was made only after contrast enhancement had been achieved by the inhalation of xenon. The different types of enhancement obtained with iodide containing contrast media and with xenon are discussed. The use of xenon to obtain further information in conditions which are inadequately elucidated by conventional CT must be balanced against its anaesthetic effects and relatively high cost.

Contrast Media↗
PubMed1978

Contrast-enhanced lesions on computerised tomography in multiple sclerosis.

Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.

Adult↗
PubMed1978

Computed tomography in spontaneous intracerebral haematomas.

The typical computed tomographic (CT) features of a recent intracerebral haematoma are a homogenous region of increased attenuation surrounded by a well demarcated relatively narrow low attenuation ring (LAR). The pathology of the LAR is controversial, but it corresponds well with a zone of ischaemic necrosis which is observed around most intracerebral haematomas exmined at autopsy. Observations are made on spontaneous intracerebral haematomas and on blood samples which confirm that extravasated blood clot undergoes a variable degree of retraction which is completed within six hours. This suggests that the LAR in recent haematoma is due to damage caused by the greater volume of the precontracted haemorrhage on the surrounding brain. CT abnormalities in intracerebral haematomas were studied; features which were useful in distinguishing spontaneous haematomas and those which affected prognosis are discussed.

Adolescent↗
PubMed1977

Comparative study of efficacy of waking and sleep recordings following sleep deprivation as an activation method in the diagnosis of epilepsy.

In the present work, on the basis of an unselected collection of patients suspected of epilepsy, the diagnostic value of waking and sleep recordings each after 24 h sleep deprivation are compared with one another. Indicative findings of epilepsy were found in 16.7% of the cases in the waking EEG after sleep deprivation. In the sleep EEG after sleep deprivation this amounted to 57.1%. These figures speak for the advantage of the second method. The result is highly significant with a chi2 value of 13.01 (p less than 0.01).

Adolescent↗