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E Wilamski

Publications and source records attributed to E Wilamski.

14 recordsLinked to original sources
PubMed1994

[Seeking a correlation between functional and imaging findings in patients after acute alcoholic pancreatitis].

The aim of the present study was to correlate the imaging and functional findings in patients who recovered from acute alcoholic pancreatitis (a.a.p.). 35 patients, 4-7 years following acute alcoholic pancreatitis underwent: secretin-cerulein test (SCT), ultrasound (US) and computed tomography (CT) of pancreas. Control group comprised 15 patients in which endoscopic, imaging and functional findings excluded organic G.I. disease. Exocrine function impairment was stated in 65.7%. US revealed pancreatic changes in 37.1% patients and CT--in 45.7%. Significant correlation between the degree of structure abnormalities in imaging techniques nad the severity of exocrine pancreatic function impairment was found (p < or = 0.05). However, in about one third of the patients studied, changes revealed in imaging techniques were not accompanied by function impairment and vice versa. Patients after acute alcoholic pancreatitis should be followed-up to early recognize and treat the revealed changes. Imaging and functional methods should be considered as strictly complementary.

Acute Disease↗
PubMedDate not supplied

The natural course of acute gallstone pancreatitis.

The aim of the study was to verify the hypothesis of complete recovery after acute gallstone pancreatitis (a.g.p) and to correlate findings of different diagnostic techniques. Thirty patients, aged 23-82 (mean 53.4 +/- 16.7), underwent a secretin-cerulein test (SCT), ultrasound (US) and computed tomography (CT) of the pancreas 6-12 months and 3-5 years after an attack of a.g.p. Exocrine pancreatic function impairment in SCT was found in 19 (63.3%) patients 6-12 months after a.g.p and in 9 (30%) patients 3-5 years after a.g.p. Imaging techniques revealed pancreatic structure abnormalities (pancreas enlargement, pseudocysts, Wirsung duct dilatation or calcifications) in 33.3% patients (US) and in 56.6% patients (CT) 6-12 months after a.g.p and in 13.3% (both US and CT) in patients 3-5 years after a.g.p. Nevertheless, the combination of recurrent attacks of abdominal pain, severe exocrine pancreatic function impairment requiring enzyme supplementation and pancreatic calcifications in imaging techniques 3-5 years after a.g.p. have been observed only in 4 (13.3%) patients. Those were the patients after multiple attacks of clinically severe, necrotic a.g.p., in which cholecystectomy has not been performed. We conclude that in most cases after acute gallstone pancreatitis pancreatic structure and function gradually return to normal. Nevertheless, patients after multiple episodes of clinically severe a.g.p., with gallbladder in situ should undergo a prospective pancreatic function and structure evaluation in order to early recognize and treat the revealed changes.

Acute Disease↗
PubMedDate not supplied

Acute alcoholic pancreatitis does not lead to complete recovery.

The aim of the study was to determine the late outcome of acute alcoholic pancreatitis (a.a.p.), as assessed by clinical examination, functional tests and imaging techniques. 47 patients, 4-7 years after a.a.p. of moderate clinical course underwent a secretin-cerulein test (SCT), glucose tolerance test (GTT), ultrasound (US) and computed tomography (CT) of the pancreas. Exocrine pancreatic function impairment was found in 63.8%, glucose impaired tolerance (GIT)-in 12.8% overt diabetes-in 17.0%. GIT and overt diabetes were found only in patients with severe exocrine function impairment requiring enzyme supplementation. Ultrasound revealed pancreatic structure abnormalities mostly pancreas enlargement, pseudocysts, structural heterogeneity, contour irregularity, Wirsung duct dilatation and calcifications in 36.21% patients and computed tomography in 44.7%. Out of 16 patients with concomittant pathology found in SCT, US and CT 14 (29.8%) suffered from attacks of abdominal pain. We conclude that, as reflected by clinical symptoms, exo- and endocrine pancreatic function tests and imaging techniques, in about one third of patients even a moderate attack of a.a.p may lead to chronic pancreatitis. We suggest that patients after acute alcoholic pancreatitis should undergo prospective evaluation including both the function and structure estimation in order to early recognize and treat the revealed changes.

Acute Disease↗