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Biomedical subjects

E Wuhib

Publications and source records attributed to E Wuhib.

4 recordsLinked to original sources

Lathyrism in rural northwestern Ethiopia: a highly prevalent neurotoxic disorder.

Lathyrism is a disorder of the central motor system, induced by heavy consumption of the grass-pea, Lathyrus sativus an environmentally tolerant legume containing the neurotoxic excitatory amino acid beta-N-oxalylamino-L-alanine (BOAA). A complete door-to-door resurvey of the Dembia and Fogera regions of northwestern Ethiopia, areas endemic for lathyrism, revealed an estimated mean disease prevalence of 0.6%-2.9%. Most patients developed the disease in the epidemic of 1976/77, although new cases appear to have occurred with an estimated mean annual incidence of 1.7:10,000. Production and consumption of grass-pea is increasing in Ethiopia, making attempts to develop low-BOAA strains to prevent lathyrism increasingly important.

Adolescent

Nutrient costing.

For the purpose of computing changes in food cost over time as well as the planning of proper nutrition education and dietary counselling, the cost of important Ethiopian foods was collected in Addis Ababa markets for three and one-half years and computed for the amount of energy and protein yield per unit price. In general, cereals and legumes faired well in their contribution of these nutrients at low cost. Certain foods, such as vetch, sugar and marmalades were also found to contribute a significant amount of nutrients at low cost. Because of the neurotoxic content in vetch and the contribution of a single nutrient as an energy source in the case of the latter two, their utilization during meal planning is subject to careful consideration. Foods of animal origin are second to last in their nutrient contribution per cost although their nutrient density makes them important in consumer demand. Root crops and vegetables that are known for their bulk are at the bottom of the list of good nutrient contributors per cost.

Dietary Services

Rarity of anaemia of pregnancy in Ethiopia.

Hb and PCV values were studied in three groups of Addis Ababa women during their last month of pregnancy and compared with those in a control group of non-pregnant Addis Ababa women. Irrespective of socio-economic group and parity, the Hb and PCV values were almost identical in all four groups. In one of the three test groups, a group of 'non-privileged' multiparae, S-iron, S-transferrin (TIBC), S-folate and S-vitamin B12 were also examined and showed normal values. These findings indicate a rarity not only of true anaemia but also of 'physiological anaemia of pregnancy'. This latter may not, therefore, be an adaptive phenomenon of regular occurrence as has usually been assumed hitherto. The explanation for the aberrant haematological behavior in pregnant women living in highland Ethiopia is probably the lifelong exposure to a very high iron intake combined with hypoxia due to the high altitude.

Adolescent