PubMed Health⌕ Search

Biomedical subjects

E Zanon

Publications and source records attributed to E Zanon.

64 records · Page 4Linked to original sources
PubMed1990

"Anti-platelet antibodies" in HIV infected haemophiliacs.

We have studied anti platelet antibodies and circulating immunocomplexes in 16 haemophiliacs with mild thrombocytopenia eight of which were infected by human immunodeficiency virus (HIV). No difference in platelet count was observed between HIV+ (143 +/- 31 x 10(9)/l) and HIV- patients (148 +/- 30 x 10(9)/l). On the contrary, HIV+ haemophiliacs had serum platelet bindable IgG (SPBIgG), normal platelet associated IgG (PAIgG), high serum IgG and circulating immunocomplexes (CIC). Considering all 16 patients serum IgG correlated with CIC (r = 0.7 p less than 0.01) and SPBIgG (r = 0.6 p less than 0.01) respectively. We obtained also a positive correlation between serum CIC and SPBIgG (r = 0.51 p less than 0.05). Immunoblotting of patients' sera showed no specific binding to target platelet antigens. In conclusion there is no evidence of HIV related immune thrombocytopenia in our haemophiliacs but the study confirms the appearance of immunocomplexes in the HIV+ subjects.

Adult↗
PubMed1990

[Percutaneous transhepatic sphincterotomy].

The authors describe the technique employed for percutaneous transhepatic sphincterotomy as performed on 3 patients with common bile duct (CBD) stones. In all patients, previous endoscopic attempt had failed for anatomical reasons (Billroth II gastric resection or partial gastric resection with Brown anastomosis), and the ampulla could not be correctly incannulated with the sphincterotome. In all patients endoscopy was useful to check the position of the diathermic loop inserted percutaneously. Complete and immediate success was obtained in all 3 cases. No major complications occurred during transhepatic treatment. To date, 1 recurrence has been observed, and the patient has been retreated with bilioplasty. All patients were followed after 5-6 months with US, plain X-rays of the abdomen and blood tests (gamma Gt, alkaline phosphatase, and bilirubinemia). The authors suggest that percutaneous transhepatic sphincterotomy be employed electively in patients with biliary tree diseases in case the endoscopic approach failes.

Aged↗
PubMed1987

[Hearing loss, a complication of antibiotic therapy in severely burned patients].

Two severely burned patients became virtually deaf during the course of treatment. The systemic and local applications of aminoglycosides and the high dosage of furosemide were the probable ototoxic agents. Renal insufficiency and persistent shock were enhancing agents. None of these factors were felt to be the individual cause of the complication, but in combination were felt to cause the deafness.

Adult↗
PubMedDate not supplied

Tubal catheterization and selective salpingography.

Hysterosalpingography with selective salpingography is by now a well-established technique in the diagnosis and therapy of some forms of female sterility especially in relation to tubal disease. The experience with a group of 302 patients with unilateral (187) or bilateral (115) proximal tubal disease, is reported. As for the catheterization of obstructed tubes, the technique was successful in about 94% of cases, while failure was observed in 6% of cases due to organic disease which hindered the transit of the angiographic guidewire or catheter. 10% of all the patients achieved spontaneous pregnancy while artificial insemination was performed in 15%. A 12-month follow-up of 10 women undergoing hysterosalpingography showed in approximately 60% of cases a new uni-or bilateral proximal tubal obstruction. No immediate or late severe procedure-associated complications were observed. Extrauterine pregnancy occurred in 2% of cases, probably due to the restored patency in tubes lacking physiologic motility.

Adult↗
PubMedDate not supplied

[Interventional radiology in the treatment of the complications from interventions on the lower urinary excretory tract].

Ureteral diversions may be complicated by strictures, hydronephrosis, pyelonephritis, lithiasis, fistulas, etc. In the last 10 years, 103 patients with 133 urological postoperative complications underwent percutaneous treatment. Most of the patients had been treated by percutaneous antegrade drainage; afterwards, stricture dilatation, ureteral stenting and stone extraction were performed. In one case a Strecker metallic stent was employed. We have successfully treated 101 of 133 complications (75.9%), with only 27 failures (20.3%). Five cases (3.8%) of lithiasis did not require percutaneous treatment. The good results obtained, the absence of major complications, the low cost and the little discomfort for the patients confirm the leading role of percutaneous treatment in complicated ureteral diversions.

Adolescent↗
PubMedDate not supplied

[Percutaneous treatment of hilar cholangiocarcinoma completed by high-dose rate brachytherapy. Experience in the first 5 cases].

Cholangiocarcinoma at the confluence of the hepatic ducts (Klatskin tumor) is a slowly growing malignancy with early onset of symptoms and poor outcome since surgery allows radical resection in only a minority of cases. Percutaneously placed biliary stents offer a good palliation, but tend to obstruct after 6-8 months; then, retreatment requires exchange of the endoprosthesis or establishment of a permanent external-internal biliary drainage which offers, in some patients, a relatively long survival. Percutaneous intraluminal HDR brachytherapy might be a valid alternative as a definitive therapy or as a method to keep metallic stents patent for a long time. Five patients with hilar cholangiocarcinoma, diagnosed by means of ultrasound, Computed Tomography, percutaneous transhepatic cholangiography and transluminal biopsy, underwent double percutaneous external-internal biliary drainage. Dummy sources were introduced into the drainage catheters to allow dose distribution planning. The stepwise progression of the miniaturized high activity Iridium source inside the applicators, introduced into the drainage catheters, was controlled and monitored by a computer equipped with dedicated software. In the radiotherapy bunker, using the remote loading technique, percutaneous intracavitary high dose rate brachytherapy was delivered at the rate of 750 cGy per fraction, prescribed at 1 cm from the center of the catheter, once a week, for 4 weeks. Nevertheless, only 4 of 5 patients underwent the complete treatment. In one case, radiation treatment was discontinued after the first session because of digestive bleeding from a duodenal ulcer, supposingly as a consequence of the decubitus of a catheter tip. CT demonstrated rapid progression of the disease with neoplastic spread to the omentum and gallbladder wall thickening; a gallbladder malignancy was then suspected and the patient was no more eligibile for brachytherapy. Subsequently, Carey-Coons endoprostheses were inserted to prevent post-actinic strictures and removed after three months. After completing radiation therapy, control cholangiograms demonstrated in all cases improvement of neoplastic strictures. The first two patients we treated show no signs of tumor recurrence at 4 and 1 months, respectively, after endoscopic removal of the stents. The third patient is still bearing 2 Carey-Coons endoprostheses to be removed after 3 months. The last patient with supposingly partial success of bracytherapy, was treated with two Strecker nitinol stents.

Aged↗
PubMedDate not supplied

[Doppler ultrasonography of the intrarenal arteries before and after radiologic treatment in obstructive uropathy].

Resistive index (RI) calculation on Doppler tracing of intrarenal arterial blood flow is a sensitive method for the early diagnosis of obstructive uropathy. However, the RI is not specific and can increase in a number of other conditions, e.g., old age, circulating endogenic factors or drugs, other nephropathies. The authors investigated RI usefulness and accuracy by measuring it both before and after the radiologic treatment of acute urinary obstruction in 21 patients, 9 of whom had chronic renal failure due to other causes, i.e., hypertension, diabetes and chronic pyelonephritis. The clinical conditions of the patients limited the feasibility of RI measurements before and after nephrostomy to 66%. In 22 kidneys in 17 patients examined before nephrostomy, the RI ranged 0.63 to 0.93 (mean: 0.80); when the obstruction was unilateral, the RI was always higher than in the contralateral kidney. In 25 kidneys in 18 patients examined after nephrostomy, the mean RI value was 0.68 (15% lower than before). Taking 0.7 as the cut-off value, RI sensitivity in detecting acute urinary obstruction was high (about 90%), while its specificity was low (about 50%); specificity increased (to about 80%) when other concomitant causes of increased intrarenal arterial resistance, e.g., other vascular or parenchymal nephropathies, were not considered. In some cases, the method was also useful in excluding the presence of recurrent obstruction after ureteral stent removal. In conclusion, Doppler US values of intrarenal arterial perfusion are indicative of acute urinary obstruction when they can be compared with those from the contralateral healthy kidney or when they can be measured, in the same patient, before and after decompressive nephrostomy. In other cases, other nephropathies and some technical limitations must be considered.

Adult↗