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Biomedical subjects

E Zderkiewicz

Publications and source records attributed to E Zderkiewicz.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[Results of surgical treatment of aneurysms of the middle cerebral artery].

The authors present a group of 38 patients with middle cerebral artery aneurysms in whom 48 aneurysms were excluded from the cerebral circulation by microsurgical techniques. In 11 cases multiple aneurysms were found. In 2 cases the wall of the aneurysm was strengthened. In the light of this material and a survey of the pertinent literature the authors analyse the relationship between the results of surgical treatment and various factors. A significant increase in postoperative mortality was found with more severe condition of the patients by the Botterell scale. The factors worsening the prognosis were also: presence of intracerebral haematoma and aneurysm location in the bifurcation of an artery. Arteriospasm increased the incidence of neurological deficits.

Adolescent↗
PubMedDate not supplied

[Multiple intracranial aneurysms].

Thirteen patients treated surgically for multiple intracranial aneurysms are described. They accounted for 12% of all patients with intracranial aneurysms diagnosed by arteriography. The incidence of multiple intracranial aneurysms, their location, surgical tactics and results of surgical intervention are discussed in the light of an analysis of own results and a survey of the pertinent literature.

Adolescent↗
PubMedDate not supplied

[Surgical treatment results in intracranial aneurysms].

Therapeutic results are reported in 115 patients operated upon for intracranial aneurysms using the microsurgical technique from Yasargil's approach. Elimination of the aneurysm from the circulation by clipping its pedicle was done in 94 cases (82%), trapping of the afferent artery (12%), in 7 cases (6%) only the wall of the aneurysmatic sac was strengthened by wrapping. A good therapeutic result was obtained in 68 patients (59.1%), satisfactory in 6 (5.2%), poor in 13 (11.3%). The overall mortality was 24.4% (28 cases) but after taking into account 4 patients dying due to extracerebral causes, the mortality caused by complications related to exclusion of the aneurysm from cerebral circulation was 20%. The factors influencing the results of surgical treatment of cerebral aneurysms are discussed in the light of the own material.

Adolescent↗
PubMedDate not supplied

[Study of cerebral blood flow by the modified method of Kety-Schmidt using the original tube for determination of nitrous oxide].

For simplifying the method of Kety-Schmidt used in measurements of cerebral blood flow a probe designed specially for this purpose was used for measuring the blood levels of nitrous oxide. The principles of the original method of Kety-Schmidt and the later proposed correction in calculations are described. The device for nitrous oxide determination called N2O-meter consists of a part for measurements and indication, to which cadmium-gold probes are attached fixed to the chambers used for blood investigations. The principle of the probe is based on demonstration of potential differences developing during N2O reduction on the cadmium electrode. Reduction of the volume of blood samples and the use of low concentration of nitrous oxide in the breathing mixture makes this method of cerebral blood flow determination safe for the patient and quick reading of the values increases the usefulness of the method under clinical conditions.

Blood Flow Velocity↗
PubMedDate not supplied

[Results of surgical treatment of post-traumatic intracerebral hematoma].

The authors discuss the results of surgical treatment of traumatic intracerebral haematomas on the basis of own material of 44 cases and a survey of literature. The rarity of this complication of injuries and the diagnostic difficulties are stressed, the usefulness of surgical approach is analysed and the prognostic importance of such factors as the clinical course of haematoma, severity of the patient's condition, and coexistence of other intracranial injuries is discussed.

Adolescent↗
PubMedDate not supplied

[Results of surgical treatment of intracranial epidural hematoma].

The authors discuss the results of surgical treatment of intracranial epidural haematomas in the light of own material of 84 cases. In relation to reports in the literature the authors call attention to diagnostic difficulties in atypical cases and discuss the importance of signs of prognostic value for the life of the patient and factors increasing mortality. The signs of poor prognosis include: respiratory disturbances, bilateral pupillary dilatation, coma with disturbances of basic vital functions and decerebrate rigidity. The mortality is increased by co-existent intracranial injuries, especially brain lacerations. The prognosis was best in cases operated upon during the lucid interval. Very good and good results of treatment were achieved in 86% of cases, satisfactory in 8%, with a general mortality of 26%, which was highest in the group with acute haematomas reaching 43%.

Adolescent↗
PubMedDate not supplied

[Epidural abscesses of the spinal cord treated surgically].

The authors discuss 5 cases of epidural empyemas of the vertebral canal in which a good surgical effect was obtained. On the basis of a literature survey and own material they discuss the aetiology of the disease, its rarity, and diagnostic difficulties caused frequently by absence of typical neurological changes, lack of systemic inflammatory reaction and primary purulent focus.

Abscess↗
PubMedDate not supplied

[Spontaneous acute subdural hematoma].

A rare case of spontaneous acute subdural haematoma is reported. Causes of non-traumatic subdural haematomas are discussed stressing the necessity of rapid surgical intervention.

Carotid Artery, Internal↗
PubMedDate not supplied

[Vasoactive neuropeptides CGRP (calcitonin gene-related peptide) and vasospasm during subarachnoid hemorrhage from ruptured intracranial aneurysm].

The authors discuss the role of active neuropeptides Calcitonin Gene-Related Peptide (CGRP) and Vasoactive Intestinal Polypeptide (VIP) in the arterial spasm caused by haemorrhage from ruptured intracranial aneurysm. These substances act as vasodilators on brain vessels. Between the first and the second week after subarachnoid haemorrhage their concentration in the periarterial nerve fibres of the big vessels is significantly low. According to the experiments, the erythrocytes are this component of the blood which causes the decrease of the number of nerve fibres containing CGRP and VIP. The clinical tests of CGRP and VIP in the treatment of the vascular spasm after subarachnoid haemorrhage are being continued.

Aortic Dissection↗
PubMedDate not supplied

[Familial occurrence of intracranial aneurysms].

Four cases of intracranial aneurysms are reported found in two families. They accounted for 1% of all patients with these aneurysms treated in that time period. The aetiology of the aneurysms, the most frequent locations in familial cases and the risk of occurrence of asymptomatic aneurysms in such families are discussed.

Adult↗
PubMedDate not supplied

[A case of multiple vascular malformations of brain and liver].

In a woman aged 45 years after a generalized epileptic seizure CT and MRI demonstrated a lesion of the type of vascular malformation of the brain diagnosed as a haemangioma by angiography which demonstrated also presence of an aneurysm of the left pericallosal artery. Abdominal ultrasonography and tomography found also hepatic haemangioma. Both cerebral vascular lesions were managed successfully in one-step operation. The hypotheses for explaining the coexistence of haemangiomas and aneurysms are discussed.

Arteriovenous Malformations↗
PubMedDate not supplied

[Direct effects of the intrathecal administration of normal saline for the brain expansion after the removal of subdural hematoma].

In a group of 360 patients the effects were studied of various management methods in case of lacking expansion of the brain after removal of chronic subdural haematoma on the therapeutic results. It was found that intrathecal infusion of normal saline was an effective procedure, with small frequency of transient complications, and was followed by a considerably lower number of re-operations than after external or internal drainage of haematoma cavity.

Adolescent↗
PubMedDate not supplied

[Spontaneous intracerebral hematomas in the material of the Department of Neurosurgery of Medical Academy in Lublin].

Between 1972 and 1991, 170 patients with spontaneous nontraumatic intracerebral haematomas were treated in the Neurosurgical Department of Medical Academy in Lublin. In 89 (52.5%) patients, the haematomas were caused by ruptured aneurysms; in 14 (8%), by angiomas; 67 (39.5%) haematomas had other etiology. Within the latter group of patients, 27% suffered from hypertension. Hypertension was also found in 15% of the patients with aneurysms and in 7% of the ones with angiomas. 34% of the haematomas were localized in the temporal lobe, 28%-in the frontal lobe, 3%-in parital lobe, 2%-in occipital lobe, 23% of haematomas were multi-lobal, 8% were found in deep brain structures, and in 2% haematomas were found in cerebellum. 128 patients underwent operative treatment, with a mortality rate of 26%, while 42 patients were treated conservatively, with a mortality rate of 19%. Basing on this material, the authors discuss indications for operative treatment of the haematomas.

Adult↗
PubMedDate not supplied

[Spontaneous intracerebral hematomas].

The choice of treatment in spontaneous intracerebral haematomas has always been controversial. As indications to surgery should be regarded: location and size of haematoma, shifting of midline structures and deterioration of consciousness. The results of treatment are worsened by deep location of haematoma, especially in thalamus and brain stem region, very big size, primary serious condition, very advanced age of the patient and some metabolic diseases like liver dysfunction. It is difficult to establish fixed rules of treatment of spontaneous intracerebral haematomas and the decision depends mainly on the experience of the surgeon.

Brain↗