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Biomedical subjects

E Zombai

Publications and source records attributed to E Zombai.

17 recordsLinked to original sources

[Basal cell carcinoma of the leg with metastases to the surrounding skin and inguinal lymph nodes].

A case of metastasizing basal cell carcinoma in a 57-year-old male is described. The primary tumor localised on the left lower leg metastasized to near skin and inguinal lymph nodes. The primary and metastatic skin tumors were excised and the defects covered by free skin grafts. Besides, the inguinal lymph nodes were block dissected and a part 10 cm long of the left calf bone was resected.

Bone Neoplasms

[Alkaptonuria-ochronosis].

The authors describe the case of a 40-year old female patient. Since her childhood she realised of her urine the black discoloration of the underwear. For about a year, without subjective complaints, blue-black color of the skin involved the axillae and pinnae. For a year appeared the increased pain of thoracal and lumbal spine column and the limitation of motion of these parts. The examination of urine, histological and electron microscopical findings, the X-ray photograph of the spinal column confirmed the diagnosis of alkaptonuria or rather congenital ochronosis.

Adult

[Disseminated cicatricial pemphigoid].

The authors describe a typical case of a rare disease, disseminated cicatricial pemphigoid. At the site of the subepidermal bulla excessive scarring in seen. Electron microscopic examination reveals elastic fibrin deposition and incipient vacuolation under the basement membrane. The indirect immunoperoxidase study shows increased numbers of positive Langerhans cells, which support their antigen-presenting role.

Antigens, Differentiation, T-Lymphocyte

[Cutaneous manifestation of Hodgkin's disease associated with verrucosis plantaris of unusual appearance].

The association of malignant lymphoma (M. Hodgkin) and verrucosis plantaris of abnormal extent was found in a young woman patient whose death was due to an underlying disease. In connection with this case the authors discuss the immunopathogenesis of malignant lymphomas (among them that of M. Hodgkin), the biology of human papilloma viruses as well as the common etiological aspects of the above immune deficient condition and the associated virus infection.

Adult

[Pemphigus herpetiformis].

We report on the typical case of a 71-year-old male patient suffering from herpetiform dermatitis. Histological investigation and immunofluorescence revealed the characteristic features of pemphigus. The symptom disappeared after therapy with corticoids.

Aged

[Hyperpigmentation of the face].

A 49-year-old male patient is presented, who developed hyperpigmented macules on the face. An exact classification of the disorder was not possible on the basis of anamnestic data, histology and electron microscopy. An attempt was made to differentiate it from other known dyschromias of the face.

Dermabrasion

[A case of erythrokeratodermia figurata variabilis successfully treated with tigason].

We report on a young man having suffered from infiltrated, scaly, hyperkeratotic, erythematous skin eruptions since his birth, varying in its course. Histologic examination revealed erythrokeratodermia. Therapy with Etretinate led to rapid regression; on keeping the maintenance dose for a year, we did not observe any recurrences. Light and electron microscopical investigations were carried out both before and 7 weeks after treatment.

Adult

[Lymphangitis carcinomatosa].

The authors present a 86 years old male patient with gradually developing upper right arm swelling. There were several hyperaemic papules, vesicles and teleangiectases on his arm. The histology revealed a lymphangitis carcinomatosa. There were no signs of any tumor, but multiple isotope accumulations in the bones. Anaplastic thyroid gland carcinoma with multiple metastases were found at autopsy.

Aged

[Acrokeratoelastoidosis].

The differential diagnosis and classification of acrokeratoelastoidosis, a relatively rare disorder, may cause difficulties. The authors therefore report the case of a 25-year-old male patient with characteristic clinical and histological signs of the disorder.

Adult

[Ashy-dermatosis--a case with spontaneous disappearance of the cutaneous lesions].

A 14-years-old girl suddenly developed typical dermal signs of ashy-dermatosis at the time of menarche. After one year, the signs began to fade and had disappeared completely two years later. The direct immunofluorescence and the ultrastructure resemble lichen planus. Endocrine factors may have played a part in the presented case, considering the sudden onset at the time of menarche.

Adolescent