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Biomedical subjects

E Zorrilla

Publications and source records attributed to E Zorrilla.

At least 19 recordsLinked to original sources
PubMed1975

Coronary insufficiency in children. Coronary arteriographic studies in two siblings from a family with hyperbetalipoproteinemia.

A family affected with hyperbetalipoproteinemia was studied. Two siblings, a boy 11 and a girl 9 years of age, with characteristic findings of homozygous type II hyperlipoproteinemia are described. The highly atherogenetic nature of this disorder is illustrated by the occurrence of progressive coronary atheromatosis in the boy, in whom two coronary arteriographic studies documented the development of progressive obstruction of two coronary arteries in the course of 2 years. During this interval angina pectoris developed followed by myocardial infarction, cardiomegaly and congestive heart failure. The sister has remained asymptomatic, with apparently normal coronary arteries at age 9 years. Phonocardiograms were suggestive of aortic valve involvement although no aortic valve gradient was demonstrated by cardiac catheterization.

Child↗
PubMed1972

Hypercalcaemia, hypophosphataemia, and inability to excrete hydrogen ions.

Investigation of a patient with hypercalcaemia, hypophosphataemia, and nephrocalcinosis failed to lead to a clear diagnosis. Neither primary hyperparathyroidism nor primary incomplete renal tubular acidosis could explain all the biochemical features, and it seems that more than one fundamental abnormality may have been present.

Acidosis↗
PubMedDate not supplied

Treatment of presumed bacterial pneumonia in ambulatory children.

In a prospective, randomized, open study, a combination of trimethoprim and rifampin (TMP/R) 20 mg/kg/day was compared with ampicillin (AMP) 150 mg/kg/day, both given orally twice daily for 10 days, for the treatment of 60 children who had mild community-acquired pneumonia. The control group comprised 112 healthy children. The overall duration of the disease was 8.5 +/- 3.6 days in the TMP/R group vs 6.0 +/- 1.1 days in the AMP group. Fever persisted for 7.0 +/- 1.8 days in the TMP/R-treated patients vs 5.2 +/- 1.0 days in the AMP-treated patients. At the end of the 10 days, nasopharyngeal cultures were negative in all patients in the AMP group and in 25 of the 30 patients in the TMP/R group. These five patients were clinical and microbiologic failures. We conclude that in infants and children with mild community-acquired pneumonia, treatment with AMP for 10 days is more effective than treatment with a combination of TMP/R for clinical cure and eradication of bacterial pathogens.

Ampicillin↗
PubMedDate not supplied

[Coronary risk factors in the Mexican population].

We review the coronary risk factors in the mexican population. The data suggest that there is a large reservoir of individuals who are candidates to develop coronary artery disease. Although coronary deaths still represent a small fraction of all deaths, mortality rates have increased recently. General preventive plans are therefore opportune and should be directed to the population at large as well as to high risk individuals and patients with clinical evidence of the disease.

Coronary Disease↗