Biomedical subjects

Eisuke Matsuda

Publications and source records attributed to Eisuke Matsuda.

7 recordsLinked to original sources

PubMed2006

Recurrent superior mediastinal primary hemangiopericytoma 23 years after the complete initial excision: a case report.

We describe here a patient with a recurrent hemangiopericytoma of the superior mediastinum 23 years after an initial complete resection. In the current biopsy specimen, the tumor cells were much more anaplastic than those seen 23 years ago. Although the patient was treated with chemotherapy, which consisted of ifosfamide and epirubicin, the tumor was unresponsive and he died 6 months later from disease progression. Careful long-term follow-up is mandatory for patients with hemangiopericytomas because recurrence with greater malignancy can develop following an extended disease-free interval.

Aged↗

PubMed2006

[Clear cell adenocarcinoma with acomponent of well-differentiated fetal adenocareinoma; report of a case].

A 69-year-old woman complaining of a cough was admitted to our hospital. Chest X-ray showed a mass in the right lower lung field. Chest computed tomography (CT) showed a tumor with notch, 3 cm in diameter, in the right lower lobe (S9-S10). The tumor was diagnosed as adenocarcinoma by the biopsy under chest CT. The patient underwent right lower lobectomy (ND2a). The tumor was whitish solid mass, 35 x 34 x 29 mm in size. Histopathologically, the tumor was diagnosed as clear cell adenocarcinoma with a component of well-differentiated fetal adenocarcinoma (WDFA), pT2N0M0, stage IB. The patient was discharged and received postoperative chemotherapy (UFT). The patient has been doing well without any tumor recurrence for 1 year postoperatively.

Adenocarcinoma↗

PubMed2006

[Complete resection of Pancoast tumor while receiving preoperative concurrent chemoradiotherapy (CCRT) as an induction therapy--report of a case].

A 60-year-old man complaining of right shoulder pain and numbness of right arm was diagnosed with Pancoast tumor (invasive right apical lung cancer). Chest CT scan showed a tumor, 5 cm in diameter, in the right apex invading the right posterior chest wall. The patient received preoperative CCRT (RT: 40 Gy/20 Fr, cisplatin: CDDP and etoposide: ETP), resulting in tumor regression (PR). The patient underwent right upper lobectomy (ND 2a), partial resection of the 1st-3rd ribs and Th 1 nerve. Pathological examination demonstrated no live cancer cells and organization of necrotic tissue in the lung and intercostal region (Ef. 3). The patient received postoperative chemotherapy (CDDP+ETP) and was discharged. He did well without any tumor recurrence for 1 year postoperatively. CCRT seems effective and is one of the standard treatments for Pancoast tumor.

Antineoplastic Combined Chemotherapy Protocols↗

PubMed2005

Chronic lung abscess with Pasteurella multocida infection.

We report a patient with chronic lung abscess due to Pasteurella multocida infection that may be caused by the contact with cows in his workplace. Despite its apparent rarity, chronic abscess due to P. multocida should be considered in the differential diagnosis of solitary pulmonary masses. This case report suggests that P. multocida infection can be potentially caused from saliva of cows as well as dogs or cats.

Bronchoscopy↗

PubMed2004

[A review and development of sentinel node navigation surgery for lung cancer].

Sentinel node navigation surgery (SNNS) for lung caner has not yet been established. Sentinel node (SN) identification using dye or radioisotope has been developed; however, the SN identification rate was less than 50% in the dye method and use of radioisotopes is strongly restricted in Japan. The novel method using a CT or MRI contrast medium are expected. A study of local immune reaction for lung cancer in SN is also a very interesting issue.

Contrast Media↗

PubMedDate not supplied

New method of visualizing lymphatics in lung cancer patients by multidetector computed tomography.

OBJECTIVE: The aim of the present study was to investigate the safety and acceptability of a new method of visualizing lymphatics, including sentinel lymph nodes (SNs), in lung cancer patients using multidetector computed tomography (MDCT). METHODS: Images were obtained using an MDCT scanner (Asteion Multi 4 Detector-Row; Toshiba) at 1, 2, and 3 minutes after percutaneous injection of 1 mL contrast medium (iohexol) near the tumor in 15 patients with small peripheral lung cancers (cT1N0M0). A lymph node was confirmed to be an SN if the attenuation was more than 30 Hounsfield units greater on postcontrast images than on precontrast images. All patients underwent surgery, and definitive lymph node staging was assessed. RESULTS: The procedure was performed safely in all patients without significant complications. Lymphatic ducts or lymph nodes were visualized in all 15 patients. The SN was identified in 14 of 15 patients (93.3%) at lymph node 14 in 4 patients, lymph node 13 in 7, lymph node 12 in 6, and lymph node 6 in 1. In 1 remaining patient, the lymphatic duct running from the tumor toward the pleura was visualized. CONCLUSIONS: Lymphatics were visualized by this method in all patients without significant complications. This method should be useful not only to detect the SNs but to visualize pathways other than through the hilar lymph nodes.

Aged↗

PubMedDate not supplied

Primary choriocarcinoma of the lung.

Primary choriocarcinoma (PCC) of the lung is extremely rare, with about 25 cases previously reported. We describe here a patient with PCC of the lung and review previously described cases to establish the clinical characteristics and most appropriate management of this disease. Survival for patients treated with both surgery and chemotherapy was longer than for patients treated with surgery alone, chemotherapy alone, or optional supportive care. Multivariate analysis of prognostic factors revealed that treatment with both surgery and chemotherapy had independent prognostic significance. Our analysis including previous cases suggests that resection followed by adjuvant chemotherapy is the most effective treatment.

Adult↗