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Biomedical subjects

Elaine Tomasi

Publications and source records attributed to Elaine Tomasi.

14 recordsLinked to original sources

Pesticides and respiratory symptoms among farmers.

OBJECTIVE: Despite the intensive use of pesticides in agriculture there are few studies assessing the risk of respiratory conditions from this exposure. The study aimed at quantifying the prevalence of respiratory symptoms among farmers and evaluating its relationship with occupational use of pesticides and the prevalence of respiratory symptoms. METHODS: A cross-sectional study was conducted among 1,379 farmers from two municipalities of Southern Brazil in 1996. Frequency and type of chemical exposure and pesticide poisoning were recorded for both sexes. All subjects aged 15 years or older with at least 15 weekly hours of agricultural activity were interviewed. An adapted questionnaire developed by the American Thoracic Society was used for the assessment of respiratory symptoms. Multivariate logistic regression analysis was carried out. RESULTS: More than half (55%) of interviewees were male. The prevalence of asthma symptoms was 12% and chronic respiratory disease symptoms was 22%. Higher odds ratios for both asthma (OR=1.51; 95% CI: 1.07-2.14) and chronic respiratory disease (OR=1.34; 95% CI 1.00-1.81) symptoms were found in women. Logistic regression analysis identified associations between many forms of exposure to pesticides and increased respiratory symptoms. Occurrence of pesticide poisoning was associated with higher prevalence of asthma symptoms (OR=1.54; 95% CI: 1.04-2.58) and chronic respiratory disease symptoms (OR=1.57; 95% CI: 1.08-2.28). CONCLUSIONS: In spite of causality limitations, the study results provide evidence that farming exposure to pesticides is associated with higher prevalence of respiratory symptoms, especially when the exposure is above two days per month.

Adolescent↗

Factors associated with condom use in women from an urban area in southern Brazil.

This study investigated the prevalence of factors associated with condom use during last sexual intercourse in 15-49-year-old women in a probabilistic sample from the urban area of Pelotas, southern Brazil. A questionnaire administered by an interviewer, investigating socioeconomic characteristics and habits, and another (self-administered) questionnaire on sexual behavior-related variables were used. Poisson regression, following a hierarchical model, was used for data analysis. 1,543 women were included, and losses and refusals amounted to 3.5%. Prevalence of condom use in last sexual intercourse was 28.0%. Condom use was positively associated with younger age, greater schooling, non-white color, single marital status, and greater number of sex partners in the previous three months. This suggests that the group most vulnerable to STDs/AIDS due to lack of condom use is white, adult women, in stable unions, with fewer sexual partners.

Acquired Immunodeficiency Syndrome↗

Health information technology in primary health care in developing countries: a literature review.

This paper explores the debate and initiatives concerning the use of information technology (IT) in primary health care in developing countries. The literature from 1992-2002 was identified from searches of the MEDLINE, Latin American and Caribbean Health Science Literature Database (LILACS), Cochrane Library and Web of Science databases. The search identified 884 references, 350 of which were classified according to the scheme described by the Pan American Health Organization (PAHO). For the analysis of advantages, problems and perspectives of IT applications and systems, 52 articles were selected according to their potential contribution to the primary health-care processes in non-developed countries. These included: 10 on electronic patient registries (EPR), 22 on process and programmatic action evaluation and management systems (PPAEM) and 20 on clinical decision-support systems (CDS). The main advantages, limitations and perspectives are discussed.

Decision Support Systems, Clinical↗

[Rural work and pesticide poisoning].

Pesticide use is intensive in Brazilian agriculture. Population-based studies on the characteristics of pesticide use and pesticide poisoning are scarce. This study describes the profile of occupational exposure and pesticide poisoning incidence. Farm characteristics and pesticide occupational exposure were evaluated using a cross-sectional design. Among 1,379 farmers/farm workers, annual incidence of pesticide poisoning was 2.2 episodes per 100 exposed. Based on Poisson regression, applying pesticide, reentering crop fields after spraying, and working with pesticides on more than one farm were the types of exposure that presented a positive correlation with pesticide poisoning. The results may be useful for planning activities aimed at reducing occupational pesticide poisoning among rural workers.

Adolescent↗

Breastfeeding and breast cancer: a case-control study in Southern Brazil.

To investigate the relationship between breastfeeding and breast cancer in Southern Brazil, a case-control design was employed, with two age-matched control groups. A total of 250 cases of breast cancer were identified in women from 20 to 60 years of age, with 1,020 hospital and community controls. The main study variables were occurrence of breastfeeding and duration of breastfeeding. A multivariate conditional logistic regression analysis was employed. According to the results, breastfeeding did not have a protective effect against breast cancer. The odds ratio (OR) for women who breastfed was 0.9 (95% CI: 0.8-1.2) compared to women who did not breastfeed. For women who breastfed for six months or less, the OR was 1.0 (95% CI: 0.6-1.8). In pre-menopausal women who breastfed for more than 25 months, the OR was 0.95 (95% CI: 0.5-3.5), and in post-menopausal women OR was 1.27 (95% CI: 0.5-3.1), compared to women who had not breastfeed.

Adult↗

[Adolescent clients of primary health care services. How do they live? Why do they seek help, and how do they express themselves?].

The objective of this study was to characterize adolescent clients of community-based primary health care services in order to understand: 1) how they express themselves when they seek medical help; 2) the health care they receive; and 3) key social and family factors. Among 35 urban primary care services belonging to the municipal public health department in Pelotas, Rio Grande do Sul State, Brazil, 10 were randomly selected, and all individuals between 13 and 19 years of age who had previously had an appointment with a non-psychiatric physician were interviewed during a three-month period (n = 463). Use of the services has more of a more curative than preventive focus. Males seek medical help less frequently and mainly due to physical complaints. Females tend to express themselves on the basis of sexual problems. Few adolescents expressed their emotional problems, although some mentioned family and school problems as well as stressful situations.

Adolescent↗

[Risk factors for small-for-gestational age births among infants in Brazil].

OBJECTIVE: To assess the risk factors for small-for-gestational-age (SGA) births. METHODS: All live births occurring in the city of Pelotas, Brazil, between October and December 1993 were identified and mothers interviewed soon after delivery. Birthweight was recorded by the maternity staff. Gestational age was obtained from the mothers' recall of their date of last menstrual period. SGA was defined as a birthweight below the 10th percentile for gestational age and sex, according to the reference developed by Williams. Chi-square test and logistic regression were used in the crude and multivariate analysis, respectively. RESULTS: In all, 1082 births were identified. The prevalence of SGA was 13.1%. Even after adjusting for possible confounding variables, the odds ratio for SGA among those infants whose family income was <1 minimum wage was 8.81 (95% CI, 1.12-69.46) times higher than among those for infants with a family income > or = minimum wage. An antenatal care of low quality was associated with an odds ratio of 3.28 (95% CI, 1.09-9.91) for SGA. Short maternal stature and maternal smoking during pregnancy were also associated with SGA births. CONCLUSIONS: Low socioeconomic status, maternal smoking during pregnancy, maternal height and an antenatal care of low quality are the main risk factors for SGA births.

Brazil↗

Implementation of the WHO Multicentre Growth Reference Study in Brazil.

The World Health Organization (WHO) Multicentre Growth Reference Study (MGRS) South American site was Pelotas, Brazil. The sample for the longitudinal component was drawn from three hospitals that account for approximately 90% of the city's deliveries. The cross-sectional sample was drawn from a community survey based on households that participated in the longitudinal sample. One of the criteria for site selection was the availability of a large, community based sample of children whose growth was unconstrained by socioeconomic conditions. Local work done in 1993 demonstrated that children of families with incomes at least six times the minimum wage had a stunting rate of 2.5%. Special public relations and implementation activities were designed to promote the acceptance of the study by the community and its successful completion. Among the major challenges of the site were serving as the MGRS pilot site, low baseline breastfeeding initiation and maintenance rates, and reluctance among pediatricians to acknowledge the relevance of current infant feeding recommendations to higher socioeconomic groups.

Brazil↗

[Software program to systematize data for planning public health actions].

OBJECTIVE: To describe and evaluate a software program to provide basic health care teams with primary health services data. METHODS: It was described the PACOTAPS (software program for primary health care), developed using Visual Basic 5.0, and secondary data and outpatient care demand modules were tested in a basic health care unit in Pelotas, Brazil. Age/gender structure of the reference population was obtained from secondary data. Outpatient care demand allowed the characterization of all 4,170 visits carried out in a month by analyzing Outpatient Care Files. RESULTS: Age and gender distribution as well as main diagnoses and referrals were identified for all patients seen at the health care unit. In addition, there were detected differences among the health care centers due to either different organization and care models or as a result of different actual needs of improvement in patient register systems. CONCLUSIONS: PACOTAPS, a user-friendly software program, can contribute to health care unit management evaluation within the national Unified Health System (SUS). The availability of an electronic tool combining resources allows decision making in healthcare facilities, and even at municipal health policy level, to be based on more adequate and effective data.

Adolescent↗

Gender differences in the use of alcohol and psychotropics in a Brazilian population.

This cross-sectional, interview-based survey aimed to assess the use of licit substances in terms of gender and sociodemographic factors in the city of Pelotas, southern Brazil. Subjects aged 15 years and over and living in urban areas were eligible and a total of 1277 subjects were interviewed. The prevalence of alcohol consumption was 54.2%; 11.9% (21.7% of men and 4.1% of women) reported potentially harmful levels of alcohol use ("at-risk alcohol intake"); 4.2% were classified as manifesting alcohol dependence by CAGE questionnaire. At-risk alcohol intake and subjects with a positive CAGE score were more common among males aged 35-54 yrs. Among the youngest age group, the prevalence of CAGE positive score was similar for males and females, while subjects with lower educational levels showed a higher prevalence. Women were more likely than men to report the use of psychotropic drugs (15% vs. 7%). These results highlight the importance of substance use in Brazil, and suggest that gender differences must to be taken into consideration when planning intervention programs in developing countries.

Adolescent↗

Factors associated with risk behaviors for sexually transmitted disease/AIDS among urban Brazilian women: a population-based study.

BACKGROUND: The proportion of women among persons with sexually transmitted disease (STD)/AIDS in Brazil is increasing rapidly, and studies are needed to understand risk behaviors. GOAL: The goal of this study was to identify factors associated with risk behaviors for acquiring STD/AIDS among women aged 15 to 49 years in Pelotas, Brazil. STUDY DESIGN: A representative sample of women was surveyed by means of interviewer-administered and self-administered confidential questionnaires. Of the women we sought to include, 3.5% refused and 1543 participated. RESULTS: Risk behaviors included nonuse of condoms (72%); first intercourse before the age of 18 years (47%); use of drugs or alcohol by the partner (14%) or by the woman (7%); multiple partners (7%); and anal sex (3%). The risk score was significantly associated with being younger than age 30 years, having <5 years of schooling, being divorced or separated, and being a smoker. CONCLUSION: Preventive strategies should prioritize efforts toward young women, those with little schooling, smokers, and those who are divorced or separated.

Acquired Immunodeficiency Syndrome↗

[Sensitivity and specificity of screening cutaneous pre-malignant and malignant lesions].

OBJECTIVE: The incidence of melanoma is increasing worldwide, prevalence of malignant epithelial tumors is high and early diagnosis reduces significantly the morbi-mortality of these diseases. The purpose of the study is to estimate the prevalence of pre-malignant and malignant skin lesions and to determine the sensitivity and specificity of screening tests. METHODS: A cross-sectional population-based study was carried out using 48 census tracts randomly selected from urban zone of southern, Brazil. A total of 2,112 dwellings were visited and 1,292 individuals aged 50 years or more were interviewed. The questionnaire consisted of specific questions about new skin lesions in the last six months and/or the presence of lesions on exposed areas. Those who answered affirmatively were referred to the university's outpatient clinic for medical skin examination (gold standard). For assessing specificity the same doctors investigated a sub-sample of those who replied negatively to the questionnaire. RESULTS: The prevalence of pre-malignant and malignant skin lesions was 20.7%. The screening sensitivity was 20.1%, specificity 86.9%, positive predictive value 29%, negative predictive value 80.4%, and accuracy 72.9%. Using different cut-off points, the maximum sensitivity value was 38.8% and specificity remained almost the same. CONCLUSIONS: The study showed a high prevalence of skin lesions both pre-malignant and malignant in adults. Skin lesion screening revealed low sensitivity and unsatisfactory specificity, regardless the cut-off points set.

Brazil↗

[Self-assessment of STD/AIDS vulnerability among women, Brazil].

OBJECTIVE: To investigate risk behaviors and self-assessment of the vulnerability to sexually transmitted diseases (STD) and acquired immunodeficiency syndrome (AIDS) among women. METHODS: A systematic sample including 48 of 281 census tracts in the urban area of Pelotas, Brazil, was selected. There were interviewed 1,543 women, aged between 15 and 49 years, who had ever been sexually active. Risk behaviors were assessed using a confidential questionnaire that consisted of three sections: socioeconomic profile, interviewers' and self-administered questions. Data analysis was conducted using Epi-Info software, version 6.0. Statistical analysis was carried out using Kappa test and odds ratio. RESULTS: Of all women in the sample, 64% considered impossible or almost impossible for them to acquire an STD or AIDS. The main risk behaviors were non-use of condoms in their last intercourse (72%); onset of sexual activity before age 18 years (47%); drug or alcohol use by the partner (14%) or the woman (7%) before their last intercourse; two or more partners in the last three months (7%); and anal sex in the last intercourse (3%); 44% reported two or more risk behaviors. Using a risk score of two or more points as the gold standard, sensitivity and specificity of self-assessment were 41% and 67%, respectively. CONCLUSIONS: Self-assessment of vulnerability is not an adequate indicator of STD and AIDS vulnerability since women do not have an appropriate perception of their risks.

Acquired Immunodeficiency Syndrome↗

[Infantile colic incidence and associated risk factors: a cohort study].

OBJECTIVE: To assess the incidence of infantile colic and its determinants. METHODS: Between May and July 1999, the research team performed daily visits to the three main maternities of Pelotas. All women were interviewed after the delivery and their infants were targeted for follow-up at three months. Colic was defined according to Wessel. The following risk factors were evaluated: social class, mother's educational level, parents' age, parents' divorce, changes in the parents' relationship during pregnancy, type of delivery, reproductive history, quality of prenatal care, previous abortion, previous stillbirths, previous newborn with health problems, gender, and infant's feeding pattern. Chi-square test was used to compare proportions and conditional logistic regression was applied in the multivariate model. RESULTS: We managed to follow 1,086 of the 1,195 infants. At the three months visit, 80.1% of the mothers reported that their infants had had colic. On the other hand, only 16.3% was considered as having colic according to Wessel criteria. Mother's educational level, father's age, type of delivery and breast-feeding duration remained in the multivariate model. Even after controlling for possible-confounding factors, the chances of having colic was 1.86 times higher among non-breastfed infants than among breastfed infants. CONCLUSIONS: Most mothers misclassify the occurrence of colic. Breastfeeding is the main protective factor.

Adult↗