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Biomedical subjects

Elaine Wirrell

Publications and source records attributed to Elaine Wirrell.

21 records · Page 2Linked to original sources

Seizure-alerting and -response behaviors in dogs living with epileptic children.

There is little evidence for the ability of dogs to anticipate human seizures. Families of epileptic children were surveyed to investigate seizure-related behaviors in dogs. Approximately 40% of families owned a dog, about 40% of these had seizure-specific behavior, and about 40% of these (approximately 15% overall) showed anticipatory ability. Anticipation occurred early and was both sensitive and specific. Quality of life was higher in families with a dog that responded to seizures.

Adolescent↗

Stroke after varicella vaccination.

Two children presented with acute hemiparesis 5 days and 3 weeks following varicella vaccination. Both showed unilateral infarction of the basal ganglia and internal capsule, a distribution consistent with varicella angiopathy. Both children had small patent foramen ovale (PFO), and one child also had severe iron-deficiency anemia, which may have predisposed the patient to this adverse effect.

Chickenpox Vaccine↗

Unique clinical phenomenology can help distinguish primary from secondary generalized seizures in children.

The physical manifestations a seizure produces provide critical information. It is assumed that all generalized convulsions are ostensibly the same, regardless of whether they are primary or secondary generalized seizures. We undertook a pilot study to determine if the clinical phenomenology of secondary generalized seizures in children with epilepsy is different from classic descriptions of generalized tonic-clonic convulsions. A data capture sheet was created and applied to the video-electroencephalographic (EEG) records of 64 secondary generalized seizures from 13 children with intractable and/or refractory epilepsy. Many features of secondary generalized seizures were different from traditional descriptions of generalized convulsions. In 100% of cases, the mouth either remained open or repeatedly opened and closed rather than slamming shut. In 77% of cases, a variety of late motor activities were seen to occur after the seizure activity had ceased and the EEG record was quiet. The clinical features of a generalized convulsion in a child, especially mouth opening and late motor events, can be useful in establishing the origin as either focal or primary generalized.

Adolescent↗