Can scleromyxedema be differentiated from nephrogenic fibrosing dermatopathy by the distribution of the infiltrate?
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Biomedical subjects
Publications and source records attributed to Elizabeth K Satter.
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We present the case of a 25-year-old man who presented with a slowly enlarging nodule on the upper lip. This nodule first appeared after minor trauma to the area. Our original differential diagnosis included foreign body granuloma, mucocele, inclusion cyst, and adnexal tumor. Histopathology results showed an encapsulated tumor consisting of 2 discrete lobules composed of numerous aggregates of cuboid epithelial cells with tubuloalveolar structures and keratinous cysts within a chondroid stroma-consistent with a chondroid syringoma. We compare and contrast the clinical and histologic characteristics of chondroid syringomas (arising from sweat glands) with those of pleomorphic adenomas (arising from salivary glands).
A 7-year-old Filipino girl presented to the dermatology clinic with a slowly enlarging plaque on the inner aspect of her upper left arm. Although she had this lesion since birth, it had gradually enlarged and become indurated and slightly painful. The histopathologic examination showed a vascular proliferation within the dermis, with a "cannonball" appearance consistent with a tufted angioma. We review the literature and discuss the clinical presentation of this rare vascular tumor.