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Biomedical subjects

Elsie G Culham

Publications and source records attributed to Elsie G Culham.

6 recordsLinked to original sources

Functional mobility and postural control in essential tremor.

OBJECTIVE: To evaluate functional mobility and postural control in participants with essential tremor (ET). DESIGN: Cross-sectional cohort study. SETTING: Motor performance research laboratory. PARTICIPANTS: Sixteen participants with ET including head tremor (age, 59.4+/-12.0 y), 14 participants with ET and no head tremor (age, 57.1+/-15.9 y), and 28 healthy controls (age, 58.4+/-12.4 y). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: We assessed the Timed Up & Go, time to ascend and descend stairs, Dynamic Gait Index, and Berg Balance Scale (BBS). Participants completed the Activities-specific Balance Confidence Scale and the Human Activity Profile. We assessed postural control using center-of-pressure measures from force platform recordings of quiet standing in 5 conditions. RESULTS: Participants with ET including head tremor performed worse than controls on all functional mobility performance and self-report measures (P<.05) except the BBS and stair descent time. Mean performance of ET participants without head tremor was intermediate between the other 2 groups. Sway speed measures of postural control showed similar patterns, but no significant group differences in post hoc analysis. There were no statistically significant or clinically important correlations between measures of tremor status and functional mobility status. CONCLUSIONS: Participants with ET show reduced functional mobility, especially those with head tremor.

Cohort Studies↗

Balance score and a history of falls in hospital predict recurrent falls in the 6 months following stroke rehabilitation.

OBJECTIVE: To investigate predictors of recurrent falls in adults who return to community dwelling after stroke rehabilitation. DESIGN: Prospective observational study. SETTING: Community. PARTICIPANTS: Fifty-five adults with stroke (mean age +/- standard deviation, 68.1+/-12.8y). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Baseline measures included balance, gait speed, muscle strength and tone, activity level, hemianopia, visual contrast sensitivity, hemineglect, medication use, fear of falling, and depression. Participants kept a 6-month prospective falls diary after discharge from rehabilitation. RESULTS: Twenty-five (45%) participants reported falling, 12 had recurrent falls (> or =2 falls), and 13 fell once. Participants who fell recurrently had histories of falling during hospitalization or rehabilitation, poorer physical function measures, were taking more medications, and were more likely to have hemineglect than participants who fell once or did not fall (P<.05). A history of falling in the hospital or during rehabilitation, combined with poor balance (either Berg Balance Scale score <49 or step test score <7), predicted recurrent falls with sensitivity and specificity values greater than 80%. CONCLUSIONS: Falls are a common occurrence after stroke. The predictive model developed can be used to identify people who are likely to have recurrent falls in the 6 months after stroke rehabilitation.

Accidental Falls↗

Reliability and validity of ankle proprioceptive measures.

OBJECTIVE: To determine the reliability and validity of ankle proprioceptive measures. DESIGN: Reliability was assessed between test occasions. Construct validity was addressed by the ability of measures to differentiate among groups. SETTING: Laboratory of an educational institution. PARTICIPANTS: Eight healthy adults were recruited into each of 3 groups: (1) young (20-39y), (2) middle-aged (40-59y), and (3) older adults (>or=60y). Four subjects from each group (n=12) participated in retesting. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Threshold for perception of passive movement, error in active reproduction of position, error in reproduction of velocity, and error in reproduction of torque. RESULTS: Intersession reliability was excellent (intraclass correlation coefficient [ICC] range, .79 - .95) for threshold for perception of movement, error in active reproduction, error in velocity reproduction, and error in dorsiflexion torque reproduction; intersession reliability was good for error in reproduction of plantarflexion torque (ICC=.72). Threshold for perception of movement differed between groups 1 and 3 and between groups 2 and 3 (P<.05). Error in reproduction of position was greater in group 2 than in group 1 (P<.05). CONCLUSION: Differences in proprioception between the older and the 2 younger groups were best detected by using threshold for perception of passive movement.

Adult↗

Reducing fear of falling in seniors through education and activity programs: a randomized trial.

OBJECTIVES: To determine the relative effect of education and activity programs on fear of falling, balance, strength, and health status. DESIGN: A randomized intervention trial with two groups (education and activity); evaluators were blind to group allocation. SETTING: Motor performance laboratory at Queen's University. PARTICIPANTS: Thirty-eight community-dwelling seniors who reported a fear of falling and activity restriction but were free of neurological and mobility-limiting orthopedic conditions. INTERVENTIONS: Programs designed to reduce fear of falling were delivered weekly to groups of three to five seniors for 8 weeks, each session lasting 1 hour. The activity program included low-resistance exercises and weight-shifting activities. Education focused on identifying and reducing risk factors for falls. MEASUREMENTS: Balance confidence, activity level, limits of stability (LOS), isokinetic strength, and health status were measured twice preintervention (baseline), postintervention, and 6 weeks later. RESULTS: Both programs reduced fear of falling (P <.006) as ascertained from the balance confidence scores. Differential effects were observed in LOS (P <.05); activity improved balance, whereas education led to modest declines. Gains in perception of health status were limited to physical health for the activity group and mental health for the education group. Benefits were generally sustained at follow-up. CONCLUSION: Improved balance confidence is not intervention-specific, but associated changes in physical ability and health status are a function of the composition of the intervention program.

Accidental Falls↗

Static and dynamic biomechanics of foot orthoses in people with medial compartment knee osteoarthritis.

OBJECTIVE: Gait biomechanics (knee adduction moment, center of pressure) and static alignment were investigated to determine the mechanical effect of foot orthoses in people with medial compartment knee osteoarthritis. DESIGN: Repeated measures design in which subjects were exposed to three conditions (normal footwear, heel wedge and orthosis) in random order. BACKGROUND: The knee adduction moment is an indirect measure of medial compartment loading. It was hypothesized that the use of a 5 degrees valgus wedge and 5 degrees valgus modified orthosis would shift the center of pressure laterally during walking, thereby decreasing the adduction moment arm and the adduction moment. METHODS: Peak knee adduction moment and center of pressure excursion were obtained in nine subjects with medial compartment knee OA during level walking using an optoelectric system and force plate. Static radiographs were taken in 12 subjects using precision radiographs. RESULTS: There was no difference between conditions in static alignment, the peak adduction moment or excursion of the center of pressure in the medial-lateral direction. No relationship was found between the adduction moment and center of pressure excursion in the medial-lateral plane. The displacement of the center of pressure in the anterior-posterior direction, measured relative to the laboratory coordinate system, was decreased with the orthosis compared to the control condition (P=0.036) and this measure was correlated with the adduction moment (r=0.45, P=0.019). CONCLUSIONS: The proposed mechanism was not supported by the findings. The reduction in the center of pressure excursion in the anterior-posterior direction suggests that foot positioning was altered, possibly to a toe-out position, while subjects wore the orthoses. Based on the current findings, we hypothesize that toe-out positioning may reduce medial joint load. RELEVANCE: Knee Osteoarthritis is the most common cause of chronic disability amongst seniors. Developing inexpensive, non-invasive treatment strategies for this large population has potential to impact health care costs, quality of life and clinical outcomes.

Aged↗

Balance, muscle strength, and fear of falling in older adults.

This study examined balance ability, lower-extremity muscle strength, fear of falling and their inter-relationships in 40 community-dwelling older adults (>65 years). Subjects who self-identified either as being fearful of falling or not (no concern) were screened to exclude those with known risk factors for falling. Limits of stability, maximal isometric strength, gait speed, and fear of falling were contrasted between groups (27 control subjects, 13 fearful subjects). Those fearful of falling demonstrated smaller center of pressure (COP) excursions in anterior, left, and right directions (p<.0001) and used a smaller percentage of their base of support during maximal weight shifting in combined anterior-posterior and right-left directions (p<.001) compared to the control group. Strength did not differ between groups, but was associated with the ability to shift the COP in the anterior-posterior direction (p<.05). Fear of falling also related to weight shifting ability (p<.017). Seniors fearful of falling demonstrated limitations in balance ability and balance confidence that could not be explained by muscle weakness.

Aged↗