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Elzbieta Hassmann-Poznańska

Publications and source records attributed to Elzbieta Hassmann-Poznańska.

At least 19 recordsLinked to original sources

[The high position of the jugular bulb in children].

INTRODUCTION: Variations of the vascular structures related to the temporal bone may cause important problems in diagnosis, treatment planing and surgery. A high jugular bulb is not an uncommon anomaly. It has been reported to occur in up to 6% of temporal bones. A high jugular bulb is often discovered as an asymptomatic, incidental finding. Case reports indicate that abnormal location of the jugular bulb may be the cause of some audiological problems. Conductive hearing loss in association with this anomaly may occur, but has been reported infrequently in the literature. MATERIAL AND METHODS: Two children with high jugular bulb are presented. RESULTS: One boy presented as a profuse bleeding from the right middle ear space after raising a tympanomeatal flap during surgery due to bilateral retraction pockets. Another one had unilateral conductive hearing loss with abberant, bluish mass seen behind tympanic membrane. CT revealed high position of jugular bulb in those patients. Results of otoscopic, audiological and radiological examinations are presented. CONCLUSION: ENT specialists and otologic surgeons should be aware of this entity to perform differential diagnosis of conductive hearing loss and avoid penetration of the jugular bulb during surgery.

Adolescent↗

[Analysis of usefulness of central auditory processes tests in children].

INTRODUCTION: Diagnostic of central auditory processing should be done in some group of children, especially with learning disabilities. MATERIAL AND METHODS: The audiological examination was performed in the group (n=24) of pupils from first class of secondary school (13-14 years) without any otological and neurological problems. The battery of audiological tests was used: pure tone, impedance and speech audiometry, two tests with low redundant speech: filtered speech (FS) and compressed sentences, sequencing tasks (FPT, DPT) and ABR. Normal answer: in FS - 80% correctly repeated words, FTP and DPT 75% correctly repeated sequences. RESULTS: Results of this examination were referred to the scores of test after primary school (max 40 points). Children were divided into 3 groups: group III (33-40 points), group II (21-32), group I (0-20). Because seven children havenít had stapedial reflex we put them into special group - NR group. Tympanometry and pure tone audiometry were normal in all children. Speech audiometry was performed in intensity 30dB and correct answers were repeated in 80-100%. In compressed sentences test answers of 22 children were normal. The average dyscrimination score were: FS g. III 90%, g. II 84,3%, g. I 77,5%; FPT 89,2%, 72,9%, 62,5%; DPT 82,5%, 71,4%, 62,5%. The percentage of normal answer were: FS g. III 100%, g. II 100%, g.I 75%, FPT 100%, 42,9%, 25%, DPT 66,7%, 42,9%, 25%. The comparison between group I-III and NR was performed. The average dyscrimination score FS g. I-III 84,7%, g. NR 71,4%; FPT g. I-III 76,2%, g. NR 72,1%; DPT g. I-III 73,5%, g. NR 50,7%. The percentage of normal answer were: FS g. I-III 94,1%, g. NR 42,9%; FPT g. I-III 58,8%, g. NR 28,6%, DPT g. I-III 47,1%, g. NR 28,6%. CONCLUSIONS: In central auditory tests (FS, FPT, DPT) worse results were in children without stapedial reflex. Good pupils (group III) had better results than poor ones (group I). The better results in audiological tests, the better scores in school test.

Acoustic Impedance Tests↗

[The cytofluorometric opinion of expression of adhesion molecules CD11a and CD54 on lymphocytes T and B in children's hypertrophied adenoids, which are sick on the otitis media with effusion].

INTRODUCTION: Otitis media with effusion (WZU) is highly prevalent among young children. The hypertrophied adenoid favorables to development (WZU). The pharyngeal tonsil delivers the essential lymphocytes for developed immunological answer. The migrations of lymphocytes to pharyngeal tonsil and to places inflammatory proceed with part of adhesive molecules (CD11a, CD54) presented on lymphocytes. The aim of this study was examination the percentage of the lymphocytes CD4+, CD8+ and lymphocytes B with expression of adhesion molecules ICAM-1 (CD54) and LFA-1 (CD11a). We examined their expression in hypertrophied adenoid by children with otitis media with effusion. MATERIAL AND METHODS RESULTS: In investigations was showed statistically significant decrease of percentage of lymphocytes CD4+CD11a+ and CD8+CD11a+ and increase of percentage of lymphocytes CD19+CD54+ in otitis media with effusion in comparison to group with hypertrophied adenoid. CONCLUSIONS: Molecule adhesive ICAM-1 and LFA-1 fulfills important part in many immunological processes proceed to pharyngeal tonsil. The considerably lower percentage of lymphocytes T CD4+ and CD8+ with expression LFA-1 in hypertrophied adenoids is possibly of causes of incorrect their immunological answer, and the same factor favourables to prolonging the otitis media with effusion at children.

Adenoidectomy↗

[Lymphocyte subpopulations in the surface secretion on the adenoid].

The significance and protective efficacy of surface secretions on mucosal membranes in the upper airways are well recognized. The aim of our study was to reveal the role of the adenoids as a source of cellular components in the mucosal secretion. The adenoid removed because of its hypertrophy and the samples of surface secretions taken by "imprint method" described by Ebenfelt et al. from the group of 38 children were examined. By flow cytometry the lymphocyte subsets with following antigens: CD3, CD4, CD8, CD19, CD23, CD16+56, CD45RA, CD45RO, HLA-DR were analyzed. The results were compared between the groups of younger and older children and in the group of concomitant otitis media with effusion (OMS) and pure adenoid hypertrophy. The percentage of lymphocyte subsets in adenoid and secretion were similar, except for lymphocytes Th with memory phenotype which were more numerous in the adenoid and lymphocytes B CD23+ which were more numerous in the secretion. In the adenoid the percentage of T and Th lymphocytes increased with age and the percentage of B lymphocytes decreased. In the secretion the percentage of lymphocytes Th and B CD23+ was higher among older children. In cases of otitis media with effusion higher percentage of lymphocytes B (CD19+ and CD19+CD23+) and lower of lymphocytes Ts and Th with naive phenotype were observed in the secretion. In adenoid however lower percentage of lymphocytes B and higher of lymphocytes Ts was observed in cases of OMS.

Adenoidectomy↗

[Expression of receptor CD23+ on B lymphocytes in hypertrophied adenoids of children with otitis media with effusion].

Tonsil pharyngeal is stimulated chronic by pathogens can be causes this hypertrophied; whose often is companions to otitis media with effusion. Subpopulation dominates in tonsil pharyngeal are lymphocytes B, and their markers activation are expression of antigen CD23+. The aim of this study was finding dependence between otitis media with effusion and coexistent hypertrophy adenoids, and percentage of lymphocytes CD19+ with expression of antigen CD23+ in hypertrophy adenoids. In the study showed higher significant percentage of lymphocytes CD19+ CD23+ at children in otitis media with effusion (20.08+/-2.93) with reference to comparative group, which was only hypertrophy adenoid (18.16+/-2.25). Percentage lymphocytes B (CD23+) were the highest (20.01+/-5.81) in children subgroup above 5 years old with otitis media with effusion, and lowest (17.36+/-2.78) in children comparative subgroup above 5 years old. As regards on different functions of antigen CD23+ the assessment of percentage lymphocytes B with expression of CD23+ can be additional marker in course immunological and inflammatory processes to occur in hypertrophy adenoids at children are sick otitis media with effusion.

Adenoids↗

[Effect of the middle ear status on the recording of vestibular evoked myogenic potential--VEMP].

The aim of this study was to assess the effect of the middle ear status on the recording of air- and bone-conducted vestibular evoked myogenic potential. Forty eight children were included in the study, ranging in age from 4 to 10 years. All of the children underwent otoscopy, pure tone audiometry, tympanometry and air- and bone-conducted VEMP in response to click. There were 3 groups according to the condition of the middle ear: group I--52 ears (type A and C1 tympanogram, pure tone average < or = 20 dB), group II--23 ears (type C2 and B tympanogram, pure tone average < or = 20 dB), group III--21 (type B tympanogram, pure tone average > 20 dB). The threshold, presence of correct waveform morphology of the response and latency was evaluated. The condition of the middle ear has no significant effect on the recording of VEMP and mean level of the response threshold with bone stimulation, based on the performed studies. However, with air stimulation it has effect on the recording of VEMP, increase of the mean threshold response and shortening of latency p13 and n23.

Acoustic Impedance Tests↗

[Anterior epitympanic recess--CT assessment].

Aeration of the middle ear is the prerequisite of it proper function. It is also necessary for successful surgical reconstruction in cases of chronic otitis media. The anterior epitympanic recess (AER) has attracted the attention in recent years as possible additional route of ventilation. The preoperative axial CT scans of the temporal bones were compared with the operative findings in retrospective analysis of cases operated because of cholesteatoma. 25 ears with perforation in pars tensa and 29 ears with the perforation in pars flaccida were analysed as well as 34 healthy ears. In 1/2 of healthy ears AER consisted of a single cell and in 1/3 of multiple small cells. The structure of the AER was much more difficult to assess in cholesteatoma ears but still it was possible in more than 1/2 of them, and it did not differ significantly from healthy ears. In the majority of ears with attic cholesteatoma the structure of AER was not identified because of cholesteatoma involvement of this area. Aeration of the AER in cases of pars tensa cholesteatoma when the tympanic isthmus was closed suggests the presence of additional route of ventilation through anterior attic.

Adolescent↗

[Stickler syndrome--case report].

Stickler syndrome is an autosomal-dominant inherited disorder of connective tissue related to incorrect collagen structure. Characteristic signs include ocular, hearing, and joint and bone abnormalities. It is hard to assess morbidity of Polish population because of lack of full syndrome's expression. In this paper we report 6 years old boy, who presented features, first characterized by Stickler in 1965.

Bone Diseases↗

[Effect of the middle ear status on the recording of vestibular evoked myogenic potential--VEMP].

The aim of this study was to assess the effect of age on the recording of air- and bone-conducted vestibular evoked myogenic potential. Forty six young subjects were included in the study, ranging in age from 4 to 18 years. All of them underwent otoscopy, pure tone audiometry, tympanometry and air- and bone-conducted VEMP in response to click. Eighty six ears with normal hearing (pure tone average 20 dB) and type A and C1 tympanogram were studied. There were 2 groups according to age: group I--children aged 4-10 years--52 ears, group II--young subjects aged 11-18 years--34 ears. The threshold, the presence of correct waveform morphology of the response and the latency were evaluated. Above parameters were examined at 95 dB and 100 dB (nHL) air conducted click intensity and 60 dB (nHL) bone conducted click intensity. The age has no significant effect on the percentage of the recording of VEMP and the level of the response threshold with air stimulation, based on the performed studies. However, the age has effect on the prolongation of latency p13 and n23 both with air and bone stimulation. We paid attention to the lower percentage of the recording of bone-conducted VEMP in young subjects aged 11-18 years.

Acoustic Impedance Tests↗

[Computerised tomography in pre-operative imaging of middle ear cholesteatoma].

Computed tomography is today the best method of imaging to study chronic middle ear diseases. The aim of this study was to assess the diagnostic value of CT scan in cases of middle ear cholesteatoma in children. The preoperative CT scans were compared with the operative findings in retrospective analysis of 60 ears operated between 1998-2001. Our results show good radiosurgical correlation in cholesteatoma for most middle ear structures except for the integrity of long process of incus. The disadvantage of CT scans is inability to distinguish between cholesteatoma, granulation tissue and effusion. CT scans are an important investigative tool prior to cholesteatoma surgery.

Adolescent↗

[Markers of epidermal proliferation in middle ear cholesteatoma].

Middle ear cholesteatoma is characterized by the presence in the middle ear cavity of a stratified squamous epithelium with keratin deposits which by constant proliferation leads to extensive bone destruction. The goal of this study was to evaluate, by immunohistochemical study, the expression of epithelial markers of proliferation--Ki-67 and PCNA in the matrix of cholesteatoma. The materials used in this study were 16 acquired cholesteatoma tissues collected from patients in the age 6-17 years during surgery. The specimens from the skin of the external ear canal were employed as the control. In the immunohistochemical specimens staining intensity and distribution of Ki67 and PCNA positive cells in various layers of the epithelium were assessed in three stages scale. The results were compared to the clinical parameters such as--type of cholesteatoma (pars flaccida or tensa), presence of ear discharge, degree of ossicular destruction and involvement of attic and mastoid. In the cholesteatoma matrix Ki-67 and PCNA positive cells were present in basal and suprabasal cell layers and also more superior layers, unlike the control skin were only basal cells show positive staining. The number of positive cells and intensity of staining was also greater in the cholesteatoma matrix than in skin of external auditory meatus. No correlation was found between results of immunohistochemical examination and clinical parameters.

Adolescent↗

[Venous malformations of the parotid gland].

We describe two cases of venous malformations in the parotid gland that were operated on due to cosmetic reasons. We present the main differences between hemangiomas and vascular malformations and we also emphasize the importance of correct diagnosis in vascular lesions what is crucial for selection of appropriate treatment.

Adolescent↗

[Incidence of coexisting sensorineural hearing loss and secretory otitis media].

There are currently no standard guidelines for assessing hearing in children who are evaluated for tympanostomy tubes. We describe the results of audiologic testing on 587 children, age 2 months to 17 years admitted to Pediatric Otolaryngology Department Białystok for treatment of secretory otitis media. Ten children (1.7%) were found to have previously unrecognized sensorineural hearing loss. In four cases total unilateral deafness, in six others moderate to severe sensorineural bilateral hearing loss was diagnosed. Three other children referred to our clinic as sensorineural hearing loss were found to have secretory otitis media as the only or coexisting cause of deafness. Results of our study show the importance of age--appropriate hearing assessment as part of diagnostic procedure for secretory otitis media.

Adolescent↗

[Assessment of hearing in children with infantile cerebral palsy. Comparison of psychophysical and electrophysical examination].

Assessment of hearing in children with various types of cerebral palsy was the aim of the study. The audiologic and laryngologic examinations were performed in 32 children with cerebral palsy. Audiologic examinations encompass impedance audiometry, otoacoustic emissions (DPOAE), brainstem evoked audiometry (ABR) and also psychophysical studies depending on possibility of co-operation with children--tonal and speech audiometry. On the ground of psychophysical studies hypacusis was recognised in 37.5% of children. In 25% of cases tonal audiometry could not be done because of mental status of the child. Hypacusis was most common in extrapyramidal type of cerebral palsy. Abnormal morphology of ABR was observed in 71.9% of cases, in 18.7% of them it could be explained by the threshold of hearing. There was always lack of stapedial reflex in cases with abnormal morphology of ABR. In some cases auditory neuropathy could be recognised on the basis of audiological examinations. In many cases the discrepancies between psychophysical and objective methods of investigation were observed. Results of hearing examinations in children with cerebral palsy should be evaluated very carefully on the basis of cross checking principle because of observed inconsistencies in audiometric tests.

Adolescent↗

[Bacterial flora of hypertrophied tonsils in children with secretory otitis media].

The potentially pathogenic bacteria: Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pneumoniae are the major bacterial flora of hypertrophied tonsils. In children suffering from otitis media with inflammatory effusion an unfortunate decreased physiological flora of Streptococcus viridans and Neisseria is observed.

Adolescent↗

[Laser myringotomy].

The aim of the study was assessment of the qualities of laser-assisted myringotomy (LAM) as a treatment for acute and secretory otitis media. Laser-assisted myringotomy was performed on 65 children (113 ears) mean age 6.2 years diagnosed with secretory otitis media (80%), recurrent secretory otitis media (11%) and acute otitis media (9%). Myringotomy was performed under general anesthesia using the OtoLAM device (ESC/Sharplan, Israel). In 64 ears pressure equalisation tubes were inserted after fenestration of the tympanic membrane with laser. Adenoidectomy alone or with tonsillectomy was performed at the same time in 51 cases. Laser tympanostomies remained patent for 7-32 days. All tympanostomies healed with no noticeable scarring. LAM appears to be a safe, and easy to performed, alternative technique in the treatment of otitis media.

Acute Disease↗

[Lymphocyte subpopulations in middle ear effusions].

The aim of this study was to identify lymphocytes subpopulations in 55 middle ear effusions and peripheral blood samples from 33 children undergoing myringotomy for otitis media with effusion. CD3+, CD4+, CD8+, CD19+ and NK cell populations were investigated using three-colour monoclonal antibody and flow cytometry to quantitative estimation. CD3+ cells were the predominant cell type in effusions (mean 63.3%). Percentage CD4+, CD8+ cells and CD4+/CD8+ ratio was significantly higher in middle ear effusions than in blood. Lymphocyte subset was compared between 22 pairs of effusions from each patient. Percentage of each cells did not differ significantly. The results of this study indicate local regulation of lymphocyte profile in middle ear effusions and the same stadium of immune response in two ears of the same patient.

Antibodies, Monoclonal↗