Biomedical subjects

Emel Soykan

Publications and source records attributed to Emel Soykan.

6 recordsLinked to original sources

PubMed2007

Trabeculectomy with mitomycin C in secondary glaucoma associated with Behçet disease.

PURPOSE: To determine the outcome of initial trabeculectomy with mitomycin C (MMC) in the management of secondary glaucoma associated with Behçet disease (BD) in a 1-year follow-up period. METHODS: Twenty-three eyes of 13 cases with secondary glaucoma associated with BD, were evaluated prospectively. They underwent primary trabeculectomy with MMC. The operative success was defined as an intraocular pressure (IOP) < or =20 mm Hg (+/- medical therapy) in the absence of phthisis and without the necessity of further surgery for glaucoma and success rates at the postoperative first day, first month, sixth month, and first year were determined. RESULTS: Success was achieved in all of the eyes (100%) at the postoperative first day and month, in 21 eyes (91.3%) at the postoperative sixth month and in 19 eyes (82.6%) at the postoperative first year. The mean preoperative IOP was 30.9+/-5.3 mm Hg under the mean 3.3+/-0.7 antiglaucoma medications but it reduced to 16.8+/-3.1 mm Hg under the mean 1.7+/-0.8 medications at the postoperative sixth month and 18.5+/-3.2 mm Hg under the mean 2.6+/-1.1 medications at the postoperative first year. CONCLUSIONS: Trabeculectomy with MMC provides reduction of IOP and the number of antiglaucoma medications in cases with secondary glaucoma associated with BD in a 1-year follow-up period.

Adolescent↗

PubMed2006

Short-term side effects of 0.2% alcohol-free chlorhexidine mouthrinse used as an adjunct to non-surgical periodontal treatment: a double-blind clinical study.

BACKGROUND: The aims of this clinical study were to evaluate the short-term subjective (by means of questionnaire) and objective (by means of clinical examination) side effects of 0.2% chlorhexidine (CHX) mouthrinse without alcohol used as an adjunct to non-surgical periodontal treatment and to elucidate the relationship between the subjective and objective evaluations. METHODS: This was a randomized, double-blind, placebo-controlled clinical trial with two groups: 1) the test group, rinsing with the test product (0.2% CHX without alcohol) twice per day for 1 week, and 2) the control (placebo) group, rinsing with a placebo solution twice per day for 1 week. Following the start of rinsing, patients were subjectively and objectively evaluated for the presence and severity of side effects (pain, burning sensation, pruritus, dryness of mouth, taste disturbance, mucosal irritations, and discoloration of tooth and tongue surfaces) at days 1, 3, and 7 of the rinsing period. The presence of subjective and objective side effects of the groups was compared via use of chi2 and Fisher exact tests. Analysis of the subjective and objective side effects within the evaluation periods was done by McNemar test. Spearman correlation analysis was used to assess the relationships between the subjective and objective side effects. RESULTS: None of the patients in either group complained of dryness of the mouth. The most commonly reported side effect was the change in color of the labial and buccal mucosa, particularly of the gingiva, after day 3 of rinsing. There were significant (r=0.308 to 0.835; P<0.05) correlations between the discolorations of tongue and tooth surfaces reported by the patients and clinically detected at all evaluation periods. There was a significant and positive relationship between the subjective side effects and the soft tissue irritations when the duration of rinsing increased. CONCLUSION: Within the limits of this clinical evaluation, rinsing with 0.2% alcohol-free CHX for 1 week caused more irritation to oral mucosa, greater burning sensation, and increased altered taste perception compared to the placebo rinse.

Adolescent↗

PubMed2004

Goldenhar's Syndrome (oculo-auriculo-vertebral dysplasia) with congenital facial nerve palsy.

Goldenhar's Syndrome (oculo-auriculo-vertebral dysplasia) is a wide spectrum of congenital anomalies that involves structures arising from the first and second branchial arches. In this report, a case of a male infant, with the features of hemi facial microsomia, anotia, vertebral anomalies, congenital facial nerve palsy and lagophthalmos is described. Although the syndrome itself is not uncommon, the presence of congenital facial nerve palsy, which has been reported in rare cases, prompted this case report.

Facial Nerve↗

PubMed2004

The influence of occlusal loading location on stresses transferred to implant-supported prostheses and supporting bone: A three-dimensional finite element study.

STATEMENT OF PROBLEM: Information about the influence of occlusal loading by location on the stress distribution in an implant-supported fixed partial denture and supporting bone tissue is limited. PURPOSE: The purpose of this study was to investigate the effect of loading at 1 to 3 different locations on the occlusal surface of a tooth on the stress distributions in an implant-supported mandibular fixed partial denture (FPD) and surrounding bone, using 3-dimensional finite element analysis. MATERIAL AND METHODS: A 3-dimensional finite element model of a mandibular section of bone (Type 2) with missing second premolar and its superstructures were used in this study. A 1-piece 4.1 x 10-mm screw-shape ITI dental implant system (solid implant) was modeled for this study. Cobalt-Chromium (Wiron 99) was used as the crown framework material and porcelain was used for occlusal surface. The implant and its superstructure were simulated in a Pro/Engineer 2000i program. Total loads at 300 N were applied at the following locations: 1) tip of buccal cusp (300 N); 2) tip of buccal cusp (150 N) and distal fossa (150 N); or 3) tip of buccal cusp (100 N), distal fossa (100 N), and mesial fossa (100 N). RESULTS: The results demonstrated that vertical loading at 1 location resulted in high stress values within the bone and implant. Close stress levels were observed within the bone for loading at 2 locations and 3 locations; the former created the most extreme stresses and the latter the most even stresses within the bone. With loading at 2 or 3 locations, stresses were concentrated on the framework and occlusal surface of the FPD, and low stresses were distributed to the bone. CONCLUSION: For the loading conditions investigated, the optimal combination of vertical loading was found to be loading at 2 or 3 locations which decreased the stresses within the bone. In this situation, von Mises stresses were concentrated on the framework and occlusal surface of the FPD.

Aluminum Silicates↗

PubMed2002

Finite element analysis of forces created by root separation and resection modelling.

Natural teeth with a healthy periodontal support exhibit stress transfer when functional forces are applied to them. These stress patterns show considerable variations during differing treatment modalities, which may influence both the tooth and supporting alveolar bone. The purpose of this study was to evaluate variations in the stress transfer under functional loads on first molars with periodontal furcation involvement, which were treated either with by root resection or root separation. This study used a two dimensional mathematical model of a mandibular first molar that was subjected to either a root separation or a root resection procedure. An evenly distributed dynamic load (600 N) was applied on two buccal cusps and distal fossae of the molar in centric occlusion. The analysis was performed using an IBM-compatible computer running standard analysis software. It was found that in the root resection model the stress values were maximum on the centre of rotation, and compressive stresses increased towards the middle of the cervical line. For the root separation model, the maximum shear stress values were observed in the distal portion, and a uniform stress distribution was observed in the mesial portion. Shear stress values for bone increased towards the centre in the bifurcation area. The outcomes of this study may be useful as a guide in clinical restorative procedures.

Compressive Strength↗

PubMedDate not supplied

Phacoemulsification cataract extraction and intraocular lens implantation in patients with Behçet's disease.

BACKGROUND AND OBJECTIVE: To evaluate the outcomes of phacoemulsification cataract extraction and intraocular lens implantation in patients with Behçet's disease. PATIENTS AND METHODS: This prospective study was based on 40 eyes of 34 patients with Behçet's disease who underwent phacoemulsification cataract extraction and intraocular lens implantation between May 2000 and February 2003. Their postoperative ocular complications and visual outcomes were observed during a mean follow-up period of 18.35 +/- 6.17 months (range, 6 to 32 months). RESULTS: Postoperative visual acuity increased in 29 eyes (72.5%) and was 20/40 or better in 18 eyes (45%). It decreased in 7 eyes (17.5%), resulting in a visual acuity of 20/400 or worse. The most frequent postoperative complication was posterior capsular opacification, which developed in 15 eyes (37.5%). Other complications were posterior synechiae formation in 7 eyes (17.5%), severe inflammation in 5 eyes (12.5%), cystoid macular edema in 5 eyes (12.5%), epiretinal membrane in 3 eyes (7.5%), and optic atrophy in 2 eyes (5%). CONCLUSION: With appropriate preoperative and postoperative suppression of inflammation, phacoemulsification and intraocular lens implantation are safe procedures leading to visual improvement in patients with Behçet's disease without preexisting fundus lesions.

Adult↗