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Biomedical subjects

Emese Balogh

Publications and source records attributed to Emese Balogh.

4 recordsLinked to original sources

Image overlay guidance for needle insertion in CT scanner.

We present an image overlay system to aid needle insertion procedures in computed tomography (CT) scanners. The device consists of a display and a semitransparent mirror that is mounted on the gantry. Looking at the patient through the mirror, the CT image appears to be floating inside the patient with correct size and position, thereby providing the physician with two-dimensional (2-D) "X-ray vision" to guide needle insertions. The physician inserts the needle following the optimal path identified in the CT image rendered on the display and, thus, reflected in the mirror. The system promises to reduce X-ray dose, patient discomfort, and procedure time by significantly reducing faulty insertion attempts. It may also increase needle placement accuracy. We report the design and implementation of the image overlay system followed by the results of phantom and cadaver experiments in several clinical applications.

Biopsy↗

Image overlay for CT-guided needle insertions.

OBJECTIVE: We present a 2D image overlay device to assist needle placement on computed tomography (CT) scanners. MATERIALS AND METHODS: The system consists of a flat display and a semitransparent mirror mounted on the gantry. When the physician looks at the patient through the mirror, the CT image appears to be floating inside the body with correct size and position as if the physician had 2D 'X-ray vision'. The physician draws the optimal path on the CT image. The composite image is rendered on the display and thus reflected in the mirror. The reflected image is used to guide the physician in the procedure. In this article, we describe the design and various embodiments of the 2D image overlay system, followed by the results of phantom and cadaver experiments in multiple clinical applications. RESULTS: Multiple skeletal targets were successfully accessed with one insertion attempt. Generally, successful access was recorded on liver targets when a clear path opened, but the number of attempts and accuracy showed variability because of occasional lack of access. Soft tissue deformation further reduced the accuracy and consistency in comparison to skeletal targets. CONCLUSION: The system demonstrated strong potential for reducing faulty needle insertion attempts, thereby reducing X-ray dose and patient discomfort.

Animals↗

Histological studies on embryonic development of the rabbit heart.

Two experiments were performed to evaluate the normal development of the rabbit heart. In the first experiment the most intensive period of heart development was determined in rabbit embryos. The second experiment studied the most intensive period of heart development, determined in the first experiment, by concentrated sampling at 8-hour intervals. After cutting open the uterine wall opposite the discoid placenta, rabbit embryos were removed from the ampullae of the uterus using capillary tubes, under stereomicroscope at fivefold magnification. The embryos were subsequently placed into 4% formalin solution for 24 h. After fixation, slides stained with haematoxylin and eosin were made for histological examination. In the first experiment 51 embryos were examined, while during the second experiment a total of 113 embryos, representing different stages of development, were collected. Finally the data obtained on rabbits were compared with the well-known development of the heart in humans and mice.

Animals↗

Multiple cardiac anomaly in sheep: a case study and review of the literature.

A multiple cardiac anomaly in sheep is presented to show how complicated the result of abnormal development can be. The heart of a 12-hour-old sheep was fixed in 8% formaldehyde solution and subsequently dissected by an anatomical method, and the abnormalities were recorded on digital pictures. The abnormal anatomy is described and compared with the simple developmental anomalies. Developmental abnormalities were found in the distal portion of the bulbus, the aortic arches and the interatrial septum. A special type of the double-outlet right ventricle was observed, which was not a real double-outlet ventricle because it occurred in combination with pulmonary atresia. Coarctation of the aorta was seen, the ductus arteriosus was absent, and there were five vessels originating from the aortic arch instead of one vessel seen in normal cases, as a result of the abnormal development of the aortic arches.

Abnormalities, Multiple↗