Biomedical subjects

Emma Storer

Publications and source records attributed to Emma Storer.

5 recordsLinked to original sources

PubMed2005

Cutaneous leishmaniasis in Afghani refugees.

Four Afghani refugees with cutaneous leishmaniasis presented to the dermatology clinic at the Women's and Children's Hospital in Adelaide. Three of the patients had biopsy-proven cutaneous leishmaniasis that was treated initially with topical and then oral ketoconazole, without success. Intralesional sodium stibogluconate was then used for these patients with good results. The fourth patient had several plaques of biopsy-proven cutaneous leishmaniasis, for which cryotherapy was used. This was quite efficacious; however, a small area of recurrence required re-treatment. Leishmaniasis is rarely seen in Australia, but an index of suspicion is warranted when treating persons with typical clinical features who are from endemic regions.

Adolescent↗

PubMed2004

Regulation of wheal and flare by tea tree oil: complementary human and rodent studies.

When applied 20 min after injection of histamine into human forearm skin, tea tree oil (TTO) reduces the developing cutaneous vascular response. In this study, the effect of TTO on inflammatory microvascular changes was dissected at the base of an experimental blister on rat skin. 1,8-Cineole, representing 2% of TTO, reduced vascular changes induced by sensory neuropeptides released when the distal portion of a cut sciatic nerve was electrically stimulated. The pre-terminal modulatory effect of 1,8-Cineole was confirmed in tests in sensory-denervated rats. Terpinen-4-ol (approximately 40% TTO) reduced substance P-induced microvascular changes and protein extravasation by a direct nitric oxide-mediated effect on the microvasculature, without sensory nerve involvement. alpha-Terpineol (3% of TTO) regulated both pre- and post-sensory nerve terminals. In human skin, terpinen-4-ol applied 10 min after histamine injection, but not alpha-terpineol or 1,8-cineole, regulated the developing wheal and flare suggesting that the histamine-induced responses in humans (at the dose used in this study, 50 microL of 330 microM histamine) are in large part determined by histamine directly affecting the vasculature via post-terminal-mediated events. The underlying strength of these studies is the use of a well-established rat physiologic model to differentiate the mechanism of regulation of microvascular changes by modulatory agents.

Animals↗

PubMed2004

Severe contact dermatitis as a result of an antiseptic bath oil.

Siblings aged 7 and 5 years developed extensive truncal and flexural inflammation and desquamation unresponsive to standard eczema therapy. After delays in diagnosis, subsequent history revealed prior use of an antiseptic bath oil in a much stronger concentration than recommended. The case illustrates the severe irritant contact dermatitis that can arise following inadequate dilution of antiseptic bath oils, presumably as a result of skin contact with benzalkonium chloride and triclosan. Features that may direct attention to such irritant dermatitis are flexural predominance with superficial desquamation and rapid improvement after avoidance of exposure to the antiseptic solution.

Anti-Infective Agents, Local↗

PubMed2004

Contact dermatitis to alcohol swabs masquerading as vaccine allergy.

A 14-year-old girl developed an eruption on her upper arm of pruritic, follicular papules each time she received a vaccination. This was initially thought to be a local reaction to the vaccines. After a similar rash appeared at a venepuncture site, a contact allergy to the alcohol swabs used before the procedures was postulated. A repeated open application test clarified this observation.

2-Propanol↗

PubMed2003

Ticks in australia.

Ticks are blood-sucking parasites of vertebrates that may embed in human skin and are therefore of clinical relevance to dermatologists and their medical colleagues. Depending on the species involved, consequences of tick attachment vary from minor local reactions to significant systemic sequelae. It is possible to minimize morbidity by removing the tick in its entirety as soon as it is detected. Some techniques to achieve this are described. This review will aid clinicians in the recognition and practical management of tick bites in Australia.

Animals↗