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Biomedical subjects

Ercan Karaarslan

Publications and source records attributed to Ercan Karaarslan.

11 recordsLinked to original sources

Preserving the ligamentum flavum in lumbar discectomy: a new technique that prevents scar tissue formation in the first 6 months postsurgery.

OBJECTIVE: Postoperative fibrosis is one of the most important causes of failed back surgery syndrome after lumbar disc surgery. Numerous natural and synthetic materials have been investigated as means to prevent or reduce postoperative scarring after these operations. Preservation of the ligamentum flavum for this purpose has not been studied in depth. A prospective, randomized, controlled clinical study was conducted. The aim was to present a new technique for preserving the ligamentum flavum during lumbar discectomy, and to evaluate whether this helps prevent or diminish postoperative fibrosis. METHODS: Twenty patients with unilateral L5-S1 disc herniation were randomly divided into two equal groups. Group A patients underwent classic microlumbar discectomy, and Group B patients underwent the same procedure but with preservation of the ligamentum flavum. Visual analog pain scale (VAPS) scores, Oswestry scale scores, and straight-leg raising angles were recorded preoperatively and at 6 months postoperatively. Differences between the pre-operative and postoperative findings for each group were statistically compared using the Wilcoxon test. Magnetic resonance imaging was also done at 6 months to assess the extent of postoperative fibrosis, and a "scarring grade" was recorded for each patient. The group findings for this were analyzed with Levene's test. RESULTS: Both groups' clinical parameters were significantly improved at 6 months postsurgery. In Group A, the mean pre- and postoperative VAPS scores were 9.2 and 3.2, respectively (P < 0.05); the corresponding mean Oswestry scale scores were 88 and 28.2, respectively (P < 0.05); and the corresponding mean straight-leg raising angles were 290 and 630, respectively (P < 0.05). In Group B, the mean pre- and postoperative VAPS scores were 9.2 and 2.6, respectively (P < 0.05); the corresponding mean Oswestry scores were 85.2 and 22.2, respectively (P < 0.05); and the corresponding mean straight-leg raising scores were 260 and 710, respectively (P < 0.05). The mean scarring grades in Groups A and B were 1.8 and 1.0, respectively (P < 0.05). CONCLUSION: The groups both showed satisfactory clinical outcomes and the improvements were comparable; however, the group with preserved ligamentum flavum showed significantly less local fibrosis at 6 months postoperatively. The authors speculate that this surgical technique provides a physical protective barrier that can reduce or even eliminate fibrosis-related complications after lumbar disc surgery.

Adipose Tissue↗

A rare case of splenic infarct presenting with acute abdominal pain due to polyarteritis nodosa: case report and review of the literature.

A 44 year-old man presented to the Emergency Department of American Hospital with severe pain persisting in the left upper quadrant for several hours. A computed tomographic scanning (CT scan) and celiac digital substraction angiography (DSA) of the abdomen demonstrated a splenic infarct. Histopathological examinations showed diffuse acute vasculitis, thrombosis, panvasculitis which led us to diagnose the case as "polyarteritis nodosa". The diagnosis is usually difficult to establish and it is usually delayed due to variable clinical manifestations dependent on the site and the extent of arterial involvement.

Abdomen, Acute↗

ROI measurement of the signal intensity of precentral cortex in the normal brain.

OBJECTIVE: It has recently been described that perirolandic cortex generally had a low signal intensity (SI) in neurologically normal brain. The aim of this study was to confirm this finding by an objective quantitative study. MATERIALS AND METHODS: Turbo fluid attenuated inversion recovery (FLAIR) magnetic resonance (MR) images of 24 neurologically normal patients were evaluated retrospectively. Signal intensity measurements of the precentral and superior frontal cortices (SFCs) were obtained at a manually traced irregular region-of-interest (ROI). t-Test for paired samples was used to evaluate the significance of differences between signal intensity measurements. RESULTS: Mean signal intensities of precentral and superior frontal cortices were 349.5 and 380.7, respectively, on the right, and 351.7 and 374.1 on the left hemisphere. The difference between the mean signal intensities of the side-matched precentral and superior frontal cortices was statistically significant (P < 0.001). CONCLUSION: Low signal intensity of the precentral cortex (PCC) in normal brain on turbo FLAIR images is an objective finding, confirmed by ROI measurement.

Frontal Lobe↗

Perirolandic cortex of the normal brain: low signal intensity on turbo FLAIR MR images.

PURPOSE: To evaluate the signal intensity (SI) characteristics of the perirolandic cortex (PRC) in the neurologically normal population on turbo fluid-attenuated inversion-recovery (FLAIR) magnetic resonance (MR) images. MATERIALS AND METHODS: Turbo FLAIR MR images of 112 neurologically normal patients were evaluated retrospectively. SI of the PRC was graded by consensus of both authors as isointense (grade 0), mildly hypointense (grade 1), or definitely hypointense (grade 2) when compared to the SI of the superior frontal cortex. Kolmogorov-Smirnov and Kruskal-Wallis one-way analysis of variance tests were used for the statistical analysis of the differences in grades between the two sexes and between the age groups, respectively. RESULTS: PRC was isointense (grade 0) in six (5%) and hypointense (grade 1 or 2) in 106 (95%) of 112 patients. The difference in grades was statistically significant between age groups (P <.001). Grade 0 was encountered most often in older patients and grade 2 in younger patients. There was no significant difference in grades between age-matched groups of male and female patients (P =.66). CONCLUSION: On turbo FLAIR images the PRC generally has a low SI in the neurologically normal brain, and this helps as an additional landmark in identifying the sensorimotor cortex.

Adolescent↗

[Pictorial essay: Evaluation of intracranial lipomatous masses with MRI].

The lipid containing tumors of the intracranial region are rare and usually benign masses. The major lipomatous masses may be listed as lipomas, dermoid cysts, and the tumors with lipoid metaplasia, most common of which is lipomatous meningioma. MRI characteristics of these rare entities have been presented, and the underlying reasons for those appearances on MRI have been discussed in this pictorial review.

Brain Neoplasms↗

Separate origins of the left internal and external carotid arteries from the aortic arch: MR angiographic findings.

Agenesis of the left common carotid artery with independent origins of the internal and external carotid arteries arising directly from the aortic arch is an extremely rare congenital anomaly. We present MR angiographic findings in a case with agenesis of left common carotid artery that, to our knowledge, is unique by virtue of its detection and description with MR angiography.

Aged↗

Spontaneously T1-hyperintense lesions of the brain on MRI: a pictorial review.

In this work, the brain lesions that cause spontaneously hyperintense T1 signal on MRI were studied under seven categories. The first category includes lesions with hemorrhagic components, such as infarct, encephalitis, intraparenchymal hematoma, cortical contusion, diffuse axonal injury, subarachnoid hemorrhage, subdural and epidural hematoma, intraventricular hemorrhage, vascular malformation and aneurysm, and hemorrhagic neoplasm. The second category includes protein-containing lesions, such as colloid cyst, craniopharyngioma, Rathke's cleft cyst, and atypical epidermoid. The third category includes lesions with fatty components, such as lipoma, dermoid, and lipomatous meningioma. Lesions with calcification or ossification, such as endocrine-metabolic disorder, calcified neoplasm, infection, and dural osteoma, constitute the fourth category, whereas the fifth category includes lesions with other mineral accumulation, such as acquired hepatocerebral degeneration and Wilson disease. The sixth category includes melanin-containing lesions, such as metastasis from melanoma and leptomeningeal melanosis. The last category is the miscellaneous group, which includes ectopic neurohypophysis, chronic stages of multiple sclerosis, and neurofibromatosis type I. The above-mentioned lesions are presented with their typical T1-hyperintense images, and the underlying reasons for those appearances in magnetic resonance imaging are discussed.

Brain Diseases↗

Infantile refsum disease: case report.

Infantile Refsum disease is a rare inborn error of phytanic acid metabolism. It is inherited in an autosomal recessive manner and frequently causes signs and symptoms in the neonate period. The only source of phytanic acid in humans is exogenous, from diet. We report the MR imaging findings in two cases of infantile Refsum disease and note the MR imaging changes that occurred over time because of further progression of the disease. The initial diagnosis in both patients was made on basis of history, clinical findings, and biochemical studies.

Brain↗