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Biomedical subjects

Erdem Gumusburun

Publications and source records attributed to Erdem Gumusburun.

6 recordsLinked to original sources

An unusual localization of an infected urachal sinus.

Failure of obliteration of the urachus in intrauterine life results in anatomically recognizable distinct anomalies. The urachus is located between the umbilicus and apex of the bladder. However, this anatomic feature does not always exist, and this may lead to misdiagnosis of the urachal pathologies. A 5-year-old boy with infected urachal sinus is presented. The urachus showed an unusual anatomic course with its extension from the umbilicus to the right lateral side of the bladder instead of the apex of the organ.

Bacterial Infections↗

Urethral duplication.

Urethral duplication is a rare congenital anomaly. Although a number of theories have been proposed to describe the embryology of the condition, the actual mechanism of the disorder is still unclear. We report here a case of urethral duplication in a 11-year-old boy complaining of a double stream, and review the current literature on this rare entity.

Child↗

Hippocampal volume in schizophrenia and its relationship with risperidone treatment: a stereological study.

The purpose of this study was to assess the significance of the hippocampal volume differences and its relation with risperidone treatment in schizophrenia. In schizophrenic patients who were on risperidone treatment (n = 11) and in healthy volunteers (n = 11), volumes of the hippocampi were estimated using magnetic resonance images (MRIs). A detailed systematic series of coronal MRIs of the entire brain (3 mm thickness, T(1)-weighted, TR/TE 400/10 ms) was obtained for each subject. All estimations were done according to Cavalieri's method by a modified point-counting grid placed on surface areas of hippocampal slices. The mean right and left hippocampal volumes in schizophrenics and control subjects were 1059.4 and 1003.2 mm(3), and 1780.1 and 1589.1 mm(3), respectively. The corresponding coefficients of errors were 0.05 and 0.068, and 0.059 and 0.081, respectively. The volumes of left and right hemispheres were not significantly different in both schizophrenic patients and controls (p > 0.05). However, a statistically significant difference (p < 0.05) was found between hippocampal volumes of the schizophrenic patients and controls. In conclusion, the hippocampal volume of the schizophrenic patients is significantly smaller than of the healthy controls. The patients who responded well to risperidone treatment had significantly greater hippocampal volumes than the patients who did not respond properly. Thus, hippocampal volume may be a predictor of the treatment response of schizophrenics to risperidone.

Adult↗

The fibular incisura of the tibia with recurrent sprained ankle on magnetic resonance imaging.

OBJECTIVE: The aim of this study was to investigate the fibular incisura of the tibia in type I and II recurrent sprained ankle. METHODS: A total of 18 limbs (9 right, 9 left) were examined for the fibular incisura of the tibia by magnetic resonance imaging at Gunmar Magnetic Resonance Imaging Center between September 2000 to May 2001. This group consisted of 10 males and 8 females and their age ranged between 18-61 years. The control group was made up of 75 participating volunteers without previous history of trauma in the ankle. RESULTS: The measurements of the length of the anterior and posterior facets, depth of the fibular incisura of the tibia and the distance between anterior margin of the tibia and anterior margin of the fibula in the patient group were visibly different from the measurements of the control group. In recurrent sprained ankle, the anterior and posterior tubercles were lengthier, the depth of the fibular incisura of the tibia was deeper and the fibula was more anterior than the control group. The measurements of the angle between anterior and posterior facets and the vertical distance of tibiofibular overlapping in the patient group were slight different from the measurements of the control groups. CONCLUSION: These characteristics, which were observed in the recurrent sprained ankles, may be anatomically predisposed to recurrent ankle sprains.

Adult↗

The congenital absence of the radius, scaphoid, trapezium, thumb and hypoplasia of the lunate.

The congenital absence of the right radius, scaphoid, trapezium, thumb and hypoplasia of the lunate are described in a 9-year-old boy. He had full extension of his elbow, while flexion motion was limited to 90 degrees. His hand was radially deviated. The thumb was absent. The index and middle fingers were united and immobile. The ring finger had movement only at the metacarpophalangeal joint, while the little finger had full motion. Complete blood count fell within normal ranges. He had no other malformations or mental retardation. No hereditary family history was found and there was no consanguineous marriage. This case is different from cases mentioned in the literature due to lunate hypoplasia and the anomalies of the index, middle and ring fingers.

Carpal Bones↗

Single coronary artery arising from the left sinus of valsalva.

A single coronary artery is a rare congenital anomaly of the coronary arteries where only one coronary artery arises from the aortic trunk by a single coronary ostium, supplying the entire heart. We report a case of a 57-year-old woman with atypical chest pain, in whom coronary angiography showed a L-I subtype single coronary artery (arising from a single ostium in the left sinus of valsalva) without associated cardiovascular disease. The clinical significance and subtype of the single coronary artery are discussed.

Coronary Vessel Anomalies↗