Biomedical subjects

Eric E Brodie

Publications and source records attributed to Eric E Brodie.

6 recordsLinked to original sources

PubMed2006

Analgesia through the looking-glass? A randomized controlled trial investigating the effect of viewing a 'virtual' limb upon phantom limb pain, sensation and movement.

The extent to which viewing a 'virtual' limb, the mirror image of an intact limb, modifies the experience of a phantom limb, was investigated in 80 lower limb amputees before, during and after repeated attempts to simultaneously move both intact and phantom legs. Subjects were randomly assigned to one of two conditions, a control condition in which they only viewed the movements of their intact limb and a mirror condition in which they additionally viewed the movements of a 'virtual' limb. Although the mirror condition elicited a significantly greater number of phantom limb movements than the control condition, it did not attenuate phantom limb pain and sensations any more than the control condition. The potential of a 'virtual' limb as a treatment for phantom limb pain was discussed in terms of its ability to halt and/or reverse the cortical re-organisation of motor and somatosensory cortex following acquired limb loss.

Adult↗

PubMed2006

A comparison of the effects of preferred music, arithmetic and humour on cold pressor pain.

Research studies of 'audioanalgesia', the ability of music to affect pain perception, have significantly increased in number during the past two decades. Listening to preferred music in particular may provide an emotionally engaging distraction capable of reducing both the sensation of pain itself and the accompanying negative affective experience. The current study uses experimentally induced cold pressor pain to compare the effects of preferred music to two types of distracting stimuli found effective within the previous studies; mental arithmetic, a cognitive distraction, and humour, which may emotionally engage us in a similar manner to music. Forty-four participants (24 females, 20 males) underwent three cold pressor trials in counterbalanced order. The Paced Auditory Serial Addition Task provided the cognitive distraction and a choice was given from three types of audiotaped stand-up comedy. Participants provided their own preferred music. A circulating and cooling water bath administered cold pressor stimulation. Tolerance time, pain intensity on visual analogue scale and the pain rating index and perceived control were measured. Preferred music listening was found to significantly increase tolerance in comparison to the cognitive task, and significantly increase perceived control in comparison to humour. Ratings of pain intensity did not significantly differ. The results suggest preferred music listening to offer effective distraction and enhancement of control as a pain intervention under controlled laboratory conditions.

Adolescent↗

PubMed2005

Visual line bisection in sinistrals and dextrals as a function of hemispace, hand, and scan direction.

Visual line bisection was investigated in 26 sinistral and 24 dextral subjects as a function of hemispace, hand and scan direction. An ANOVA revealed significant main effects for hand preference, due to the mean bisection errors of dextral subjects being significantly leftward of those of sinistral subjects; for hand, due to the bisection errors of the left hand being significantly to the left of the right hand; and for scan, due to the bisection errors following a left scan being significantly to the left of a right scan. One significant interaction was found, that between hand and direction of scan, due to a significant difference between left and right hands following a scan from the left but not following a scan from the right. For dextral subjects the leftward bisection errors of the left and right hands following a scan from the left, but not for a scan from the right, differed significantly from the midpoint. For sinistral subjects the leftward bisection errors following a scan from the left and rightward bisection errors following a scan from the right differed significantly from the midpoint for the left hand but not for the right hand. No significant main effect or interactions for hemispace were found. This confirms that both sinistral and dextral subjects display pseudoneglect when using their preferred hand and scanning from the left. However, sinistrals, but not dextrals, will display reversed pseudoneglect when using their preferred hand and adopting a scan direction from the right. These results are discussed in terms of the interaction between three factors, whose influence can jointly and severally produce misbisections, hemispheric specialisation for visuospatial function, hemispheric activation for a manual response, and the allocation of visual attention.

Adult↗

PubMed2004

Temperature and the cold pressor test.

UNLABELLED: As a method of experimental pain induction, the cold pressor test is thought to mimic the effects of chronic conditions effectively. A survey of previous studies using the cold pressor, however, revealed a lack of standardization and control of water temperature, questioning comparability and reliability. This study reports the influence of temperature on pain tolerance and intensity by using a commercially available circulating water bath. Twenty-six participants (12 men, 14 women) underwent 4 cold pressor trials with temperature order counterbalanced across 1 degrees C, 3 degrees C, 5 degrees C, and 7 degrees C, temperatures representative of the range used in previous literature. After each cold immersion participants rated pain intensity on a visual analogue scale and the McGill Pain Questionnaire. Tolerance times were recorded for each trial. Significant main effects of temperature were found for tolerance time, with higher temperatures resulting in longer times, and pain intensity, with lower temperatures resulting in higher intensities. Gender differences were found, with men tolerating the stimulus for significantly longer than women. It was concluded that small differences in water temperature have a significant effect on pain intensity and tolerance time. The use of cold pressor equipment that ensures a precise constant temperature of circulating water is necessary to ensure comparable and reliable results. PERSPECTIVE: The cold pressor method of experimental pain induction has been widely used in the evaluation of psychological and physiological pain treatments. This article highlights the need for clear methodologic guidelines for the technique and demonstrates that very minor changes in experimental protocol can produce significant differences.

Adult↗

PubMed2003

Increased motor control of a phantom leg in humans results from the visual feedback of a virtual leg.

Although previous research reported that the visual feedback of a 'virtual arm' increased the control of a phantom arm, it did not consider that the repeated attempt to move the phantom may have contributed to the effect. Twenty-one lower limb amputees reported the response of their phantom leg during repeated attempts to move both legs in one of two conditions, a control condition in which the amputee only viewed the movements of their intact leg and an experimental condition in which the amputee additionally viewed the movements of a 'virtual' leg. It was found that viewing a virtual leg resulted in amputees reporting a significantly greater number of movements of their phantom leg than with attempted movement alone. The implications were discussed in terms of visuo-motor adaptation and theories of motor control.

Adult↗

PubMed2000

Remembering an everyday pain: the role of knowledge and experience in the recall of the quality of dysmenorrhoea.

The ability to describe the quality of a previous pain may be thought to be better if one had experienced that particular pain because information stored in episodic and/or semantic memory is available rather than if one had not and could only guess what the pain may be like on the basis of information stored in semantic memory. However research has shown that not only is the quality of labour pain poorly recalled by women who have given birth but also it is no better described by them than by women who have never given birth at all. In order to replicate this effect for an everyday pain, the ability to recall the quantity and the quality of dysmenorrhoea was measured in two groups of women. One group regularly experienced dysmenorrhoea, the other had never experienced it. Analysis of the pain intensity scores revealed that the 'pain' group reported significantly less pain 2 weeks later whereas the 'no-pain' group did not significantly differ in their rating over time. Analysis of the MPQ Descriptors chosen by subjects using Cohen's kappa resulted in 'fair' recall for both groups with no significant advantage for the 'pain' group. These results suggest that the episodic memory system plays a limited role in facilitating the recall of the quality of an often experienced pain. However the semantic memory system allows both previous pain sufferers and pain guessers to describe the core qualities of a pain to the same extent. Further research is required to explain why remembering the quality of a pain experience is not advantaged by episodic memory and what facilitates the transfer of a pain experience into semantic event memory.

Adolescent↗