Biomedical subjects

Ethan Brodsky

Publications and source records attributed to Ethan Brodsky.

3 recordsLinked to original sources

PubMed2006

3D fluoroscopy with real-time 3D non-cartesian phased-array contrast-enhanced MRA.

For optimized CE-MRA of the chest and abdomen, the scan time and breath-hold must be coordinated with the arrival of contrast. A 3D fluoroscopy system is demonstrated that performs real-time 3D projection reconstruction acquisition, reconstruction, and visualization using only the standard scanner hardware and operator console workstation. Unlike 2D fluorotriggering techniques, no specification of a monitoring slab or careful placement of the imaging volume is required. 3DPR data are acquired continuously throughout the examination using an eight-channel receiver and 1 s interleaved subframes. The data are reconstructed using 1 s segments for real-time monitoring with 0.8-cm isotropic spatial resolution over the entire torso, allowing full-volume axial, coronal, and sagittal MIPs to be displayed simultaneously with minimal latency. The system later uses the same scan data to generate high-spatial-resolution time-resolved sequences of the breath-hold interval. The 3D fluoroscopy system was validated on phantoms and human volunteers.

Artifacts↗

PubMed2005

Rapid fat-suppressed isotropic steady-state free precession imaging using true 3D multiple-half-echo projection reconstruction.

Three-dimensional projection reconstruction (3D PR)-based techniques are advantageous for steady-state free precession (SSFP) imaging for several reasons, including the capability to achieve short repetition times (TRs). In this paper, a multi-half-echo technique is presented that dramatically improves the data-sampling efficiency of 3D PR sequences while it retains this short-TR capability. The k-space trajectory deviations are measured quickly and corrected on a per-sample point basis. A two-pass RF cycling technique is then applied to the dual-half-echo implementation to generate fat/water-separated images. The resultant improvement in the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was demonstrated in volunteer studies. Volumetric images with excellent spatial resolution, coverage, and contrast were obtained with high speed. The non-contrast-enhanced SSFP studies show that this technique has promising potential for MR angiography (MRA).

Brain↗

PubMed2004

Contrast-enhanced peripheral magnetic resonance angiography using time-resolved vastly undersampled isotropic projection reconstruction.

PURPOSE: To investigate the application of time-resolved vastly undersampled isotropic projection reconstruction (VIPR) in contrast-enhanced magnetic resonance angiography of the distal extremity (single station), and peripheral run-off vasculature in the abdomen, thigh, and calf (three stations). MATERIALS AND METHODS: Time-resolved distal extremity imaging was performed using VIPR sequence through the comparison of two acquisition matrix sizes: 256 with TR/TE=3.7/1.4 msec and 320 with TR/TE=4.5/1.8 msec under the same scan time of two minutes. VIPR acquisition was combined with a bolus-chase technique to image the peripheral run-off vasculature. The time-resolved images were reconstructed using a revised sliding window reconstruction filter whose temporal aperture remained narrow for low spatial frequencies and increased quadratically to include all the projection data for high spatial frequencies. RESULTS: The new temporal filter significantly suppressed the undersampling streak artifacts and venous contamination, while maintaining a high temporal resolution. Both high spatial resolution (ranging from 1.56 x 1.56 x 1.56 mm to 1.25 x 1.25 x 1.25 mm) and high temporal resolution (three seconds per frame) distal extremity images and peripheral run-off images were generated using time-resolved VIPR acquisition, which provides isotropic spatial resolution and isotropic coverage. CONCLUSION: Time-resolved VIPR acquisition was demonstrated to be well suited for distal extremity imaging by providing isotropic spatial resolution, isotropic coverage, and high temporal resolution. The combination of time-resolved VIPR and bolus chase technique provided a novel approach for peripheral run-off examinations.

Abdomen↗