Biomedical subjects
Publications and source records attributed to Ewa Podwińska.
We present a case of a 47-year-old woman suffering from Bourneville-Pringle disease and uterus cancer undergoing radical operation. Surgery was performed under general anaesthesia and went uneventfully.
Authors present the case of Fournier's gangrene in course of perianal abscess. They pay attention to fulminant clinical course of superficial perineal fascia necrosis caused by mixed bacterial flora included aerobes and anaerobes and difficulties of treatment. They indicate the possibility of septic shock and multiple organ failure leading to death, in spite of intensive surgical and pharmacological treatment.
UNLABELLED: The aim of this study was to present our experience in the diagnostics and treatment of primary malignant thyroid lymphoma (PMTL). Five patients at the age of 48-72 years with PMTL were treated at the Department of General Surgery in Bytom in the years 1988-1999. They made up 0.04% of patients operated on at this time in our Department because of different types of goiter and 1.05% because of thyroid carcinoma. The clinical examinations included ultrasonography, radioisotope diagnostics, preoperative thin needle biopsy and hormonal examination of thyroid gland. All patients were operated on under general anesthesia and with intraoperative histopathological examination. They were treated with chemo- and/or radiotherapy in postoperative period. The appearance of PMTL was preceded by nodular goiter or Hashimoto disease. In three cases we observed neck compression symptoms and in two the dramatic course of disease. Ultrasonography revealed hypoechogenic thyroid gland with nodular structures characterized by the decreased J131 uptake. In one case thin needle biopsy confirmed the diagnosis of PMTL. Evident hypothyreosis was diagnosed in one and subclinical in two patients. Surgical treatment--partial excision of neoplastic tumor--was complicated by tracheostomy in two cases. One case with almost total resection of thyroid gland was complicated by lesion of esophagus which was sutured. After operation one patient was treated with chemotherapy, one with radiotherapy and two cases using both of methods. Three patients died: in 3rd, 32nd day and after 3 months since surgery. We confirmed the remission of the disease in two the youngest patients with not advanced state. One of them was treated with Co 60 therapy and the second one with chemotherapy according to COP and radiotherapy. CONCLUSIONS: PMTL is a rare disease and difficult to diagnose. The biopsy is useful. The treatment of PMTL combined, including surgical treatment, chemo- and radiotherapy. The prognosis is uncertain and depends on the disease period.
Unbalanced hyperthyroidism leads to the feeling of dyspnea and to the decrease of vital lung capacity. Efficacious treatment of thyrotoxicosis relieves mentioned disorders and brings normalization of ventilation parameters. The main issue of this research was the analysis of vital lung capacity in female patients with properly treated hyperthyroidism and comparison of values of these parameters among patients with balanced thyrotoxicosis, non-toxic goitre and with non-thyroid disorders. Research was conducted on 300 randomized female-patients (ASA I, II), aged 18 to 47 with surgically treated hyperthyroidism, non-toxic goitre or non-thyroid disorders. Vital lung capacity (VLC) was analyzed as absolute values and as a percent of predicted values. Statistical analysis revealed that patients in specified groups did not differ in age, weight and frequency of belonging to both ASA categories. Vital lung capacity and percent of predicted values were not significantly different in all groups. Vital lung capacity of female-patients with balanced hyperthyroidism did not differ significantly from vital lung capacity of patients with non-toxic goitre and non-thyroid disorders.