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Biomedical subjects

F A Burgener

Publications and source records attributed to F A Burgener.

At least 19 recordsLinked to original sources
PubMed1979

[Intravenous cholangiography in hyperbilirubinaemia (author's transl)].

The effect of bilirubin on biliary and renal excretion of methylglucamine-iodipamide at an infusion rate of 1.3, 2.6 and 5.2 mu mol/min/kg was studied by intravenous injection into five dogs with normal liver functions and chronic duodenal fistulas. Unconjugated bilirubin administered in a dose of 0.1 mu mol/min/kg reduced biliary iodipamide excretion and concentration significantly, but did not affect renal contrast material excretion. This indicates that the unsatisficatory radiological results of intravenous cholangiography in hepatic and obstructive jaundice depend not only on the reduced excretion capacity of the liver, but are also due to a direct inhibitory effect of bilirubin on biliary contrast material excretion. In the presence of hyperbilirubinaemia, the highest iodine concentrations in the bile were obtained with the highest iodipamide serum levels; a reduction in contrast material dose or prolongation of the period of contrast material infusion therefore does not appear to be indicated in jaundiced patients.

Animals↗
PubMed1979

[Evaluation of hepatic and renal function after visceral angiography (author's transl)].

A prospective study was carried out in 25 patients following visceral angiography using, on average, 3.5 (2.3 to 4.3) ml/kg. of sodium methyl glucamine diatrizoate 76%. No significant changes were found in the liver enzymes (SGTP, LDH and alkaline phosphatase). On the other hand, there was a significant but temporary rise of serum creatinine from 0.9 +/- 0.2 mg% to 1.2 +/- 0.3 mg% as well as transient proteinuria (7 cases) and microhaematuria (6 cases). With the usual contrast doses for visceral angiography, the kidney appears to be the critical organ. In order to reduce the risks of renal complications, contrast doses should be kept to below 4 ml/kg. if possible; angiography should be carried out only if the patient is well hydrated and the indications for angiography should be particularly stringent if there is previous renal damage.

Adult↗
PubMed1979

[Correlation between radiological, scintigraphic and histological changes in bone in rabbits following irradiation with single and fractionated doses (author's transl)].

The left hind legs of eight rabbits were irradiated with 1.750 rad in a single dose or with 4,650 rad divided over a period of three weeks. These animals, as well as four who had not been irradiated, were examined periodically radiologically and with 99m Technetium pyrophosphate scintigrams during one year. No difference could be detected between the results of the single and fractionated doses. Scintigraphically there was a biphasic increase in uptake, the first peak co-inciding with the irradiation and of vascular origin, whereas the second peak occurred at four months and was due to a change in bone metabolism. At the end of a year uptake in the irradiated limb was slightly reduced. The earliest radiological changes were found after six months, at the end of the second scintigraphic peak; they consisted of coarsening and blurring of the trabeculae, nonhomogeneous spotty mineralisation and endosteal scalloping. Six animals developed a radiation-induced bone sarcoma, first demonstrated either by scintigraphy or radiology depending on its histology. The value of combining radiological and scintigraphic examinations for the early detection of post-radiation abnormalities is stressed.

Animals↗
PubMed1979

[Nonsurgical production of intrahepatic portosystemic venous shunts in portal hypertension with the double lumen balloon catheter (author's transl)].

A nonsurgical production of intrahepatic shungs between the left portal and left hepatic vein was evaluated in twelve dogs with acute portal hypertension. Dilatation of the intrahepatic tract was achieved by means of a double lumen balloon catheter introduced into the portal system with the transjugular approach. The shunts proved to be effective in immediate reduction of increased portal pressure and no significant complications were encountered.

Animals↗
PubMed1979

Early medullary cystic disease: a urographic diagnosis?

Excretory urography of a patient with an early stage of medullary cystic disease demonstrated an inhomogeneous, streaky nephrogram confined to the medulla, presumably due to accumulation of contrast material in dilated tubules. This was seen best one to two hours after contrast injection and may represent a specific urographic finding which does not appear to have been described previously in this condition.

Adolescent↗
PubMed1979

Production of nonsurgical portosystemic venous shunts in dogs by transjugular approach.

Intrahepatic shunts between the left portal and hepatic veins were performed in 50 dogs (20 acute, 30 chronic experiments) using the transjugular approach with Dotter's coaxial catheter system. All shunts were occluded within two days; significant complications arose only after a shunt stayed in the animal a prolonged period. The intrahepatic tract wall was completely organized and fibrosed after three weeks.

Animals↗
PubMed1978

Pharmacocholangiography.

The effect of ouabain and atropine on bile flow and bile iodine concentration in intravenous cholangiography was investigated in 4 cholecystectomized dogs (20 experiments) with complete bile diversion under general anesthesia and compared to the effect of sodium taurocholate. Iodipamide was administered intravenously with an initial priming dose of 50 mg per kg followed by a constant infusion of 2 mg per min per kg. Ouabain in stepwise increasing infusion rates, .0625 to .25 microgram per min per kg, had no significant effect. Atropine infusion rates from 1 to 8 microgram per min kg increased the bile iodine concentration up to 19% but already a 14% increase with a 5% reduction in bile flow was found with the smallest atropine dose. The lowest taurocholate infusion rate resulted in the highest bile iodine concentration and lowest bile flow. It is suggested that atropine premedication and low bile salt plasma levels might improve the opacification of the biliary tree particularly in hepatic dysfunction by reducing selectively specific fractions of the basal bile flow.

Anesthesia, General↗
PubMed1978

[The value of various radiological procedures for the investigation of functional disturbances of renal transplants (author's transl)].

The value of various radiological examinations was analysed with reference to 75 renal transplants which had developed complications. If the renal poles are marked with metallic clips, the size of the transplant can be estimated by abdominal x-rays. Abnormal size was found exclusively in severe rejection reactions, but only about 50% of acute rejections showed such a change. Contrast examinations were found to be valuable in the diagnosis or exclusion of anatomically localised lesions such as obstructions or anastomotic leaks. They were unsatisfactory in the diagnosis and differential diagnosis of diffuse parenchymatous abnormalities such as rejection or damage during storage.

Abscess↗
PubMed1977

[The radiological manifestations of disseminated histiocytosis X in adults (author's transl)].

The radiological findings of disseminated histiocytosis X in twelve patients (eight men, four women) aged 16 to 61 years are described. Pulmonary manifestations (eight cases) are characterised by symmetrical, bilateral involvement with predominance in the middle and upper lung fields, with relative sparing of the bases and apices. Multiple, unsharp, localised foci up to 1 cm. characterise the acute stage, "honey-combing" (multiple, uniform cysts of about 1 cm.) characterise the chronic stage. The hilar nodes are frequently somewhat enlarged. Pneumothorax (bilateral in one case) is a not uncommon complication. Skeletal involvement is often multiple (five out of seven cases) and symmetrical. Sharply defined or diffuse areas of osteolysis measuring from several millimetres to several centimetres were found in the skull, spine, ribs, pelvis and long tubular bones, sometimes with reactive sclerosis. Pathological fractures, cortical thickening, solid periostal reactions, bone expansion and central sequestra complete the radiological picture.

Adolescent↗
PubMed1977

Acute inflammation of epiglottitis and supraglottic structures in adults.

Acute epiglottitis, an unusual cause of acute upper airway obstruction in adults, is probably more common than previously recognized. While the history and physical findings are characteristic, the clinical diagnosis is often unsuspected. Radiographic findings include swelling of the epiglottis, aryepiglottic folds, arytenoids, uvulae, and prevertebral soft tissues, with ballooning of the hypopharynx and mesopharynx and obliteration of the valeculae. The epilgottic airway may show a characteristic pencil-thin configuration due to edema.

Adult↗
PubMed1976

[The radiological manifestations of fibroxanthosarcomas (author's transl)].

The radiological findings in eight patients with fibroxanthosarcomas are described. In seven patients the primary tumour was in the soft tissues of the extremities or of the trunk. Infiltration of the primary tumour into a neighbouring bone, producing a "motheaten" appearance on the radiograph was seen in one case. A primary tumour in the mediastinum (one case cannot be distinguished radiologically from malignant lymphoma. Pulmonary metastases were found radiologically in five patients; in two they were solitary and in three patients there were multiple round foci measuring up to 8 cm. in diameter. Metastases in the lung hila and mediastinum were found only in the presence of pulmonary metastases (three cases). Pleural effusions developed in an advanced stage of the disease only (three cases). A solitary, purely osteolytic bone deposit was seen in two patients. Multiple metastases in the kidneys were hypo- or avascular, but some showed fine corkscrew vessels. On intravenous urography they could be demonstrated after reaching a considerable size (one case). A deposit in the jejunum presented as a small polyp. Two fibroxanthosarcomas developed as a second tumour within the operative field of a previous malignancy; one of these had been irradiated with 4,500 rads. All primary and secondary tumours showed extremely rapid growth. The palliative effect of radiation and chemotherapy was very variable.

Abdominal Neoplasms↗
PubMed1976

Angiographic features of malignant fibrous histiocytomas.

The angiographic findings in 2 cases of metastatic fibrous histiocytoma are discussed. A lesion in the brain was completely avascular and displaced the surrounding vessels, whereas the renal lesions were hypovascular, usually well demarcated, sometimes exhibited beak formation, and demonstrated fine, corkscrew-like tumor vessels with delayed emptying but no tumor blush or early draining veins.

Adolescent↗
PubMed1976

Pharmaco-cholangiography with anticholinergic drugs in the dog.

The effect of atropine and pipenzolate bromide (PB) in different dosage levels was investigated in intravenous cholangiography with 0.6 ml/kg iodipamide infused over 30 minutes in six cholecystectomized dogs (20-36 kg) equipped with Thomas cannulas through which the common bile duct could be cannulated. Doses of 1 mg atropine and 20 mg PB, half the dose given intravenously just prior to the contrast agent and the other half with the iodipamide infusion, had the greatest effect in decreasing the bile flow (atropine-24% at 60, PB-23% at 30 minutes) and increasing the bile iodine concentration (atropine + 16%, PB + 14%). The biliary iodipamide excretion rate was not affected.

Animals↗
PubMed1976

Analysis of the radiographically visualized deep hepatic lymph drainage in the dog.

The deep hepatic lymph drainage of 9 cholecystectomized dogs was analyzed after radiographic visualization with retrograde biliary infusion of Ethiodol. No drainage from the deep to the superficial lymph system of the liver was found with the described method. Primary stations of the deep hepatic lymph drainage are the hepatic, left gastric and splenic lymph nodes although the latter two were not always opacified. On the average 9 (6-11) hepatic lymph nodes were opacified which is a significantly higher number than previously reported. Retrograde contrast material filling of splenic, mesenteric, aortic, iliac and some intrathoracic lymph nodes occurred with various frequencies but the opacification of these nodes was usually incomplete.

Animals↗