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Biomedical subjects

F A Rodrigues

Publications and source records attributed to F A Rodrigues.

5 recordsLinked to original sources
PubMed1991

Posterior atlantoaxial arthrodesis. A simplified method.

A simplified method of posterior atlantoaxial arthrodesis allowing immediate stabilization and mobilization is described. This method of fixation has been used since 1984 in 33 cases, with the indications being nonunion of odontoid peg fractures, atlantoaxial dislocation, and other traumatic conditions about the axis. A solid fusion was noted in all 33 patients by 3 months postsurgery, and the complication rate was minimal. This method of atlantoaxial arthrodesis is simple, allows immediate mobilization, controls rotation and lateral bending, and is inexpensive.

Adult↗
PubMed1989

A sensitive bedside urine test for human chorionic gonadotrophin in suspected ectopic pregnancy.

An ultrasensitive modification of the Tandem Icon urine test for human chorionic gonadotrophin was used by clinicians, without special training, in the evaluation of 51 women with suspected ectopic pregnancy. There were 2 false-positive results. No negative results occurred in the presence of ectopic or ongoing pregnancy. A negative result (the majority of cases) is useful for excluding the diagnosis of ectopic pregnancy. The need for observation in hospital and diagnostic surgery can be greatly reduced by the use of this test in the ward or outpatient department.

Chorionic Gonadotropin↗
PubMed1989

Hypothesis: a central role for platelet activating factor in the pathogenesis of pre-eclampsia.

The pathophysiology of pre-eclampsia is uncertain, though many mechanisms have been postulated. These include an immune response to fetal or placental antigens, a thromboxane-prostacyclin system imbalance and an increase in levels of or responsiveness to angiotensin. We propose the hypothesis that platelet activating factor (PAF), a mediator of inflammatory and allergic responses, may be an important link between these pathophysiological events.

Angiotensin II↗
PubMed1988

The effect of fibrin sealant on mouse embryos.

It is postulated that ovarian hyperstimulation prior to embryo transfer results in changes in the endometrium which lead to poor adhesive properties of the endometrium. Based on the properties of fibrin sealant which is used in human operative medicine, it is believed that adhesion of embryos to the endometrium during embryo transfer may be encouraged by the addition of fibrin sealant. The purpose of this study was to assess the effects of the addition of fibrin sealant to a mouse embryo/Ham's F-10 culture medium mixture. There was no statistical difference in the number of blastocysts developing from 138 embryos in standard medium compared with 139 cultured with the addition of fibrin sealant. It is concluded that fibrin sealant is not embryotoxic, and thus following further experimentation its eventual utilization in human in vitro fertilization/embryo transfer programs appears promising.

Animals↗