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Biomedical subjects

F A Salem

Publications and source records attributed to F A Salem.

At least 19 recordsLinked to original sources

Antidiabetic effects of a dietary supplement "Pancreas Tonic".

Pancreas Tonic, a dietary supplement, contains plant products shown to possess hypoglycemic activity. This study investigated the effect of Pancreas Tonic on serum glucose, glycosylated hemoglobin, and pancreatic islet cell regeneration of rats. Results showed that body weights of three groups of rats were not significantly different from each other before the study period, and after the 12 week study, weights increased with nonsignificant difference among the groups. The diabetic group had significantly higher serum glucose levels compared with controls, and the diet-treated group had significantly lower serum glucose levels compared with the diabetic group. The diabetic group's glycosylated hemoglobin was significantly higher compared with the control group, and the diet-treated group had significantly lower glycosylated hemoglobin levels compared with the diabetic and control groups. Histological analysis of the pancreas showed a generalized reduction in size and number of islets in the diabetic group and regeneration of islet cells in the diet-treated group compared with the diabetic group. The diabetic group had a significant reduction in the number of cells compared with controls. The diet-treated group contained a significantly increased number of cells compared with the diabetic group. These data suggest that Pancreas Tonic induced an antidiabetic effect through pancreatic islet cell regeneration in experimental rats.

Animals↗

Cognitive evoked potential (P300): a metric for cerebral concussion.

Cognitive impairment has been reported to occur in minor head injury (concussion). The value of the P300 evoked potential as a measure of cerebral concussion was studied in 20 patients with minor head injury and compared with the data from 20 normal subjects. Significant abnormalities of the P300 latency and amplitude were noted in these patients in the post-concussion period. The abnormalities improved completely on repeat testing. The correlation of the P300 to other parameters of head injury is discussed. The P300 constitutes a simple laboratory test that is sensitive measure of cerebral dysfunction in concussive head injuries.

Adolescent↗

Cerebral chromomycosis.

A 52-year-old man was admitted to the hospital with headache, confusion, and early papilledema. He was receiving prednisone and azathioprine for interstitial pulmonary fibrosis. A right temporoparietal cerebral abscess was diagnosed by computed tomographic scan, brain scan, and cerebral angiography. Fungal cultures of pus obtained at operation grew a pigmented fungus, Cladosporium trichoides. Three additional abscesses were found in the right cerebellar hemisphere at autopsy after the patient died of an unrelated cause. Chromomycosis occurring at sites other than skin is extremely rare. No lesions were detected outside the CNS in our patient. C trichoides has not been previously recognized as an agent causing disease in compromised hosts.

Brain Diseases↗

Cyclic changes in cervical microflora and their effect on infections following hysterectomy.

In a prospective study the cyclic changes in the cervical microflora and the endometrial histology were correlated with the incidence of postoperative infections in 99 women undergoing elective abdominal hysterectomy. Escherichia coli and Bacteroides fragilis were isolated more frequently during the proliferative phase than during the secretory phase and, correspondingly, postoperative infections were more frequent when operated during the proliferative phase than during the secretory phase. Moderate to severe infections occurred in 31.6% of the patients operated during the proliferative phase in contrast to 18% during the secretory phase. This suggests increased host susceptibility to infection during the proliferative phase.

Adult↗

Cervical deciduosis and intraepithelial neoplasia.

With the widespread use of routine cervical cytologic screening in pregnancy and the increasing use of colposcopy, the problem of coexistent decidual and neoplastic cervical changes becomes more frequent. This case report illustrates such a problem and discusses its management.

Adult↗

Rudimentary horn pregnancy with neonatal and maternal survival.

Pregnancy in a rudimentary uterine horn is an unusual event that often terminates early in gestation with catastrophic hemorrhage. Under rare circumstances an intact rudimentary horn or a secondary abdominal pregnancy from a ruptured horn continues to term.These cases present with pain or anemia, an uncertain or abnormal fetal lie, and may be complicated by symptoms of preeclampsia. Physical examination, and ultrasonic and radiographic studies lead to the correct diagnosis. Rapid surgical intervention can result in fetal and maternal survival with preservation of fertility.

Adolescent↗

Pulmonary mycetoma due to Coccidioides immitis.

Pulmonary mycetoma due to Coccidioides immitis has been reported on three occasions. The present case is the fourth such report occurring in a patient with widely disseminated disease. Spherules and hyphae were found in the specimen. While the active pulmonary and extra-pulmonary lesions responded well to therapy with amphotericin B, resection was required to eliminate the residual mycetoma and its attendant hemoptysis.

Adult↗