Biomedical subjects

F A Treiber

Publications and source records attributed to F A Treiber.

At least 37 records · Page 2Linked to original sources

PubMed1997

Relationships between children's cardiovascular stress responses and resting cardiovascular functioning 1 year later.

Resting cardiovascular parameters were predicted from anthropometric data, resting baseline cardiovascular data, and cardiovascular responses to three laboratory stressors completed 1 year earlier. Subjects were 106 male and female children (72 Whites, 34 Blacks) aged 6-7 years at the initial evaluation. During initial testing, blood pressure, heart rate, cardiac output, and total peripheral resistance were assessed at rest and also during a forehead cold pressor task, postural change, and treadmill exercise. The same cardiovascular parameters were then assessed at rest 1 year later. After controlling for significant anthropometric measures and the pertinent previous year's resting data, systolic and diastolic responses to the cold pressor were predictive of respective follow-up resting levels. Postural change heart rate responses were predictive of follow-up resting heart rate after controlling for initial resting levels. Exercise cardiac index reactivity predicted follow-up cardiac index after controlling for earlier resting levels and adiposity. Follow-up total peripheral resistance index was predicted by earlier resting levels.

Blood Pressure↗

PubMed1997

Prediction of resting cardiovascular functioning in youth with family histories of essential hypertension: a 5-year follow-up.

Two hundred forty-six children (96 Whites, of whom 51 were males; 150 African- Americans, of whom 69 were males) with a familial history of essential hypertension (EH) were re-evaluated 5 years after an initial evaluation. During the initial visit anthropometric, demographic, and resting cardiovascular (CV) parameters (designated initial baseline levels) were assessed. These CV parameters (systolic and diastolic blood pressure [BP], heart rate, cardiac output index [CI], and total peripheral resistance index [TPRI] were also measured during postural challenge, a video game challenge, and a cold pressor task. At follow-up, resting CV parameters were again evaluated, and designated as follow-up resting levels. Moderate temporal stability (r range = .43-.56) was observed for all resting CV parameters. Mean stress responses for each CV parameter for all 3 stressors during the initial visit were positively related to the respective CV follow-up resting level. BP stress responses to postural change and video game challenge to be significant independent predictors of future resting BP after controlling for standard EH risk factors. Follow-up resting CI was not predicted by any stress responses, whereas follow-up resting TPRI was predicted by TPRI responses to the video game after controlling for standard Eh risk factors. These results contrast with those from an earlier 1-year follow-up, where stress responses for neither CI nor TPRI predicted follow-up resting levels. It appears that, as children get older, TPRI stress responses play a stronger role in vasoconstrictive function.

Journal Article↗

PubMed1996

Anthropometric, demographic, and cardiovascular predictors of left ventricular mass in young children.

Left ventricular (LV) mass is a strong independent predictor of cardiovascular morbidity and mortality. Few longitudinal studies have examined predictors of LV mass in children. This study assessed the contributions of anthropometric, demographic, and cardiovascular parameters (at rest and after exposure to laboratory stressors) as predictors of LV mass 3.6 years after the initial examination in a sample of 68 Caucasian and African-American children 7.9 +/- 0.7 years old. At the initial examination, all subjects had standard anthropometrics measured and hemodynamics assessed at rest and during 3 stressors: postural change, forehead cold stimulation, and treadmill exercise. On the follow-up examination 3 to 4 years later, echocardiographic evaluations were conducted to estimate LV mass and related LV geometry. LV mass and LV internal diameter in diastole were adjusted for linear growth (LV mass/height2.7 and LV internal dimension during diastole/height0.80, respectively). Hierarchical stepwise multiple regression analyses were conducted using parameters significant in univariate comparisons (p < 0.05). Initial weight (R2 = 0.38), height (R2 = 0.42), and cardiac output reactivity to standing and treadmill exercise (final model R2 = 0.55) were significant predictors of LV mass, whereas LV mass/height2.7 was predicted by initial adiposity (R2 = 0.07) and cardiac output and systolic pressure reactivity to postural change (final model R2 = 0.25). Follow-up relative wall thickness was significantly predicted by ethnicity (African-Americans greater than Caucasians, R2 = 0.15), adiposity (R2 = 0.20), and systolic pressure reactivity to postural change (final model R2 = 0.28). These findings suggest the potential benefit of weight control in childhood as a primary prevention for later onset of cardiovascular disease.

Anthropometry↗

PubMed1996

Young children's cardiovascular stress responses predict resting cardiovascular functioning 2 1/2 years later.

BACKGROUND: Since the pathogenesis of coronary heart disease (CHD) has its origins in childhood, researchers have increasingly evaluated CHD risk factors in youth. In this study we examined the hypothesized behavioral risk factor of cardiovascular responsivity as a predictor of very young children's resting cardiovascular functioning 2 1/2 years later. SUBJECTS AND METHODS: During an initial visit to the laboratory, 97 children (30 blacks and 67 whites, 45 boys and 52 girls) aged 6-7 years completed three laboratory stressor tests (forehead cold pressor, postural change, and treadmill exercise). A comprehensive cardiovascular assessment was conducted during the tests. Resting cardiovascular activity (baseline values) was also assessed. Follow-up resting cardiovascular parameters were measured in the laboratory 2 1/2 years later. RESULTS: Cardiovascular stress responses were predictive of cardiovascular follow-up resting levels 2 1/2 years later. Multiple regression was used to evaluate the independent predictive power of stress responses after controlling for traditional risk factors. Follow-up resting systolic blood pressure (SBP) was predicted by the SBP response to postural change and treadmill exercise. Follow-up resting diastolic blood pressure (DBP) was predicted by the DBP response during treadmill exercise, particularly for blacks. The follow-up resting heart rate was predicted by the heart rate response to the forehead cold pressor and treadmill exercise. CONCLUSION: These results show that in very young children, stress responses are predictive of resting cardiovascular functioning 2 1/2 years later. Further developmental and longitudinal investigations will determine whether such responses are predictive of later preclinical manifestations of cardiovascular disease. If so, incorporation of stress testing in a standardized risk identification protocol might aid the design and practice of cardiovascular preventive medicine.

Analysis of Variance↗

PubMed1996

Moderators of ethnic differences in vasoconstrictive reactivity in youth.

Three hundred and forty-one children (170 males and 171 females: 155 whites and 186 blacks) with a mean age of 11.2 years completed laboratory stressors of forehead cold and a video game. Impedance cardiography was used to assess total peripheral resistance indexed by body surface area (TPRI) at rest and during the stressors. Black youths exhibited greater TPRI and mean arterial pressure (MAP) reactivity to both stressors. It was hypothesized that anthropometric, demographic, lifestyle, and psychosocial variables might partially account for ethnicity differences in vasoconstrictive reactivity. Black youths' higher resting MAP and TPRI and greater MAP and TPRI reactivity to forehead cold were accounted for by anthropometric characteristics, physical activity, sedentary behavior (i.e., TV viewing) and family cohesion. The ethnic differences in TPRI and MAP video game reactivity were not accounted for by the various parameters.

Black or African American↗

PubMed1995

Temporal stability of children's cardiovascular (CV) reactivity: role of ethnicity, gender and family history of myocardial infarction.

Cardiovascular responses to three laboratory stressors (i.e., postural change, treadmill exercise, forehead cold) were evaluated in 106 children (72 Whites, 34 Blacks) who varied in family history (FH) of early myocardial infarction (53 positive FH, 53 negative FH). Subjects were evaluated on two occasions separated by one year. In general, regardless of ethnicity, gender or FH, stability of resting blood pressures (BP) and heart rates were comparable to existing data. Resting cardiac output (CO) and total peripheral resistance (TPR) stability estimates were comparable or higher than the BP estimates across groups except for the +FH subjects and males who showed poor stability to one or both parameters. Moderate stability was observed for all parameters in response to forehead cold and low to moderate stability was observed in HR, CO, and TPR postural change reactivity. The only consistent pattern of significant differences in stability estimates involved ethnicity. African-Americans exhibited significantly higher coefficients compared to Whites in TPR at rest and during postural change and forehead cold. Reasons for the low to moderate resting and reactivity stability estimates are discussed.

Black People↗

PubMed1994

Pressor reactivity, ethnicity, and 24-hour ambulatory monitoring in children from hypertensive families.

We assessed blood pressure responses of a multiethnic (Black and White) sample of 120 children of hypertensive families to orthostasis, video game, forehead cold, and dynamic exercise, and monitored the children's ambulatory pressure 24 hours later. Thirteen children were studied twice (1-year stability). The Black children exhibited higher 24-hour ambulatory systolic and diastolic pressures than the White children. Regardless of ethnicity, peak and mean systolic pressures during each task were generally positively correlated with mean systolic pressure while the children were awake and asleep. Associations between diastolic pressor responses and ambulatory measurements were somewhat dependent upon ethnicity and task. Relatively few reactivity-ambulatory correlations were significant, using pressor reactivity change scores. The children who participated twice exhibited significant 1-year stability for most ambulatory and pressor measurements. Children's pressor responses to laboratory tasks may generalize to the natural environment.

Adolescent↗

PubMed1994

Ethnic differences in the myocardial and vascular reactivity to stress in normotensive girls.

Cardiovascular reactivity to stress has been proposed as a mechanism partially responsible for the increased prevalence of essential hypertension in African-Americans compared with whites. However, few studies have examined ethnic differences in cardiovascular reactivity among women. The present study evaluated potential ethnic differences in the cardiovascular reactivity to three laboratory stressors (postural change, video game challenge, forehead cold stimulation). The sample consisted of 171 normotensive girls (74 whites, 97 African-Americans) with a mean age of 11.1 +/- 2.7 years, all with positive family histories of essential hypertension. African-American girls showed higher resting diastolic blood pressures and higher resting total peripheral resistance compared with white girls. African-American girls also exhibited higher peak responses in systolic and diastolic blood pressure and total peripheral resistance and lower cardiac index responses during video game challenge and forehead cold stressor. The findings extend previous observations of ethnic differences in blood pressure reactivity to stress and indicate that concomitant increases in total peripheral resistance appear to account for the greater blood pressure reactivity in African-American girls.

Adolescent↗

PubMed1994

The effect of adiposity on children's left ventricular mass and geometry and haemodynamic responses to stress.

This study evaluated the relationship between adiposity, left ventricular mass and geometry, and haemodynamic parameters at rest and during laboratory stressors in a sample of 69 normotensive children with positive family histories of essential hypertension. Children were classified as overweight if they were above the 85th percentile of weight-for-height for their age and gender compared to national normative data. Nineteen children (7 whites, 12 blacks) were classified as overweight and the remaining 50 (26 whites, 24 blacks) were not overweight. Overweight children were found to have higher resting systolic and diastolic blood pressures, heart rates (HR), cardiac output (CO) and stroke volumes (SV), and lower resting total peripheral resistance than the non-overweight children. No differences were noted in haemodynamic reactivity to the stressors. Echocardiographic findings indicated that the overweight children had greater left ventricular mass indexed by height2.7, interventricular septal thickness and left ventricular end diastolic diameter (LVEDD) compared to non-overweight children. These findings are the first to indicate that the higher resting pressures of overweight normotensive children are a reflection of increased normotensive children are a reflection of increased preload (i.e. greater HR, SV, CO, LVEDD). These findings point out the early deleterious effects of obesity on the cardiovascular system in the young and highlight the need for effective obesity prevention and intervention programmes.

Adipose Tissue↗

PubMed1993

Ethnicity, gender, family history of myocardial infarction, and hemodynamic responses to laboratory stressors in children.

Relationship among ethnicity, gender, grandparents' histories of early myocardial infarction, and hemodynamic responses to forehead cold and treadmill exercise were examined in 87 6-to-8-year-olds (57 White, 30 Black). Boys had greater increases in systemic vascular resistance and decreases in cardiac index to forehead cold. Girls had greater increases and quicker recovery in heart rate to dynamic exercise. Blacks had greater increases and slower recovery in diastolic pressure to exercise and forehead cold. Blacks showed greater increases and slower recovery in systemic vascular resistance to forehead cold. Positive-family-history children had greater increases in diastolic pressure and systemic vascular resistance to forehead cold and greater diastolic pressure increases to exercise. Positive-family-history Blacks had greater increases in systolic pressure to exercise and slower recovery than all other groups.

Black or African American↗

PubMed1993

Relationship between family environment and children's hemodynamic responses to stress: a longitudinal evaluation.

Because interpersonal relationships may have an impact on the risk of developing cardiovascular disease, the authors examined the prospective relationship of family functioning upon hemodynamic stress responses in 87 6- to 8-year-old children. The parents completed the cohesion, conflict, expressiveness, and control subscales of the Family Environment Scale; 2 years later, the authors assessed the children's hemodynamic responses to postural change, forehead cold stimulation, and treadmill exercise. Maternal reports of greater cohesion and expressiveness were related to less increases in systolic pressure and systemic vascular resistance in response to the forehead cold. Mothers' reports of expressiveness were related to lower systolic pressure and cardiac index reactivity to postural change. Fathers' reports of greater control were associated with greater diastolic pressure and vascular resistance increases to forehead cold and to greater vascular resistance responses to exercise. Paternal reports of greater conflict were associated with greater systemic vascular resistance increases and with lower cardiac index increases to exercise. Results suggest family functioning may predict later hemodynamic reactivity to stress. The findings are discussed in terms of previous research on parent-child interaction patterns and children's cardiovascular health.

Arousal↗

PubMed1992

The relationship of anger and child psychopathology.

This study examines the relationship of anger to child psychopathology in an inpatient psychiatric sample. Results suggest that anger as assessed by the Children's Inventory of Anger is not highly correlated with other affective experiences or behavioral dispositions, yet may provide incremental data pertinent to distinguishing children with concurrent disturbances of emotion and conduct from children with disturbances in either emotion or conduct.

Adolescent↗

PubMed1992

Hostility: relationship to lifestyle behaviors and physical risk factors.

The relationship between hostility and coronary artery disease may be partially mediated by unhealthy lifestyle behaviors. This study examined the relationship between hostility, lifestyle behaviors, and physical risk factors in 138 adult men and women. Subjects completed the Cook and Medley Hostility Scale (Ho scale) and self-reports of their dietary habits, consumption of alcohol and cigarettes, and physical activity. Recent findings indicated that a composite hostility score from three rationally derived subscales of the Ho scale tapping the dimensions of cynicism, hostile affect, and aggressiveness was a better predictor of mortality than the total Ho score. Thus, this composite measure of hostility and the total Ho score were used in data analyses. Measures of resting blood pressure, height, weight, and adiposity were also obtained. In men and women, both measures of hostility were positively associated with cholesterol intake and vigorous physical activity. Among women, both hostility measures were positively related to animal fat intake and negatively related to fiber intake. The composite measure was positively related to their resting systolic pressures. Among men, both hostility measures were positively related to cigarette smoking and sugar intake and negatively associated with systolic blood pressure and calcium intake. Findings are discussed in terms of previous research linking hostility to lifestyle behaviors and CAD.

Adult↗

PubMed1991

Family history of myocardial infarction and hemodynamic responses to exercise in young black boys.

The influence of family history of coronary artery disease on children's hemodynamic responses to exercise was examined with 25 black boys aged 7 to 10 years. Blood pressure, heart rate, cardiac output, stroke volume, and total peripheral resistance were evaluated during preexercise, peak exercise, and recovery stages. Children with a family history of CAD exhibited greater systolic blood pressure and total peripheral resistance during preexercise and peak exercise stages than did those without a family history of coronary artery disease. After controlling for preexercise differences, the group with a family history of coronary artery disease exhibited greater increases in systolic blood pressure and less attenuation of total peripheral resistance to peak exercise than the group without a family history of coronary artery disease. Cardiac output indexed by body surface area and stroke volumes were higher at all times in the group without a family history compared with the group with a family history of coronary artery disease. Findings are compared with those of adult studies in terms of influence of family history of coronary artery disease on cardiovascular reactivity to stress.

Black People↗

PubMed1991

Social support for exercise: relationship to physical activity in young adults.

BACKGROUND: Physical inactivity is an independent risk factor for cardiovascular disease, yet little is known concerning factors which influence participation in physical activity or exercise. Two studies assessed the relationships between self-reported physical activity and social support for exercise. METHOD: One study involved a biracial sample of middle-class male and female teachers (mean age = 38.5 +/- 8.9 years) and one involved a biracial sample of lower- to middle-class males and females (mean age = 35.8 +/- 5.1 years). RESULTS: In both studies the social support scales had high internal consistencies and a two-component solution identical to the original validation study. In both studies, social support for exercise positively correlated with physical activity, but the relationships were mediated by race, gender, specific types of support (i.e., family, friend), and dimensions of physical activity (i.e., global, work, sports, and leisure). In both studies, regardless of work status and race, women's overall activity, particularly during leisure time, was positively related to family support for exercise. In both studies white women's overall activity levels, especially sports and leisure activities, were positively related to friend support. In both studies, black women's sports activity was positively associated with family support. Among white men in both studies, sports activities and total energy expenditure were positively related to family and friend support. Black men's sports-related activity was positively related to family support among the teachers and to friend support among subjects in the second study. CONCLUSION: Findings are discussed in terms of future research directed toward identification of other familial and sociocultural variables which might influence individuals' involvement in physical activity.

Adult↗

PubMed1991

Examining emotional distress during pediatric hospitalization for school-aged children.

Emotional distress was examined in 80 school-aged children during pediatric hospitalization. Using multiple regression analyses, children's depressive and anxious symptoms were positively related to duration of physical symptoms and parental distress. Depressive symptoms were negatively related to age and the perceived social support available from the family. Unexpectedly, the frequency of medical procedures and previous hospitalization experiences were not associated with depressive or anxious symptoms. Because many of the children in this study had experienced enduring symptoms and frequent previous hospitalizations, it was hypothesized that they may have habituated and adjusted to many of the experiences of hospitalization and thus were not adversely affected by such experiences.

Adaptation, Psychological↗

PubMed1991

'White coat' hypertension in children.

BACKGROUND: Research with ambulatory blood pressure monitoring (ABPM) clearly demonstrates the importance of identifying "white coat" hypertension before making the diagnosis of hypertension. While the existence of white coat hypertension has been documented in adults, it is unknown whether this phenomenon is present during childhood. Therefore, the purposes of this study were to determine whether white coat hypertension exists in children with a positive family history of essential hypertension; and if it exists, to compare 24-hour ambulatory blood pressure patterns among normotensive, white coat hypertensive, and hypertensive children. METHODS: One hundred fifty-nine children (aged 5 to 15 years) participated in the study. Based on office systolic and diastolic measurements and 24-hour ABPM, subjects were placed into one of three groups: normotensive, white coat hypertensive, and hypertensive. RESULTS: Forty-four percent of 34 subjects with systolic blood pressures greater than or equal to 95th percentile were reclassified as white coat hypertensive; 56% remained hypertensive. Group comparisons of 24-hour ABPM patterns showed significant differences between groups. Also, the ABPM patterns of white coat hypertensive patients were significantly different from those of normotensive patients. CONCLUSIONS: This study documented the existence of white coat hypertension in children and showed that white coat hypertensive children were significantly different from normotensive and hypertensive children on most comparisons of 24-hour ABPM data. Also, when age and sex were controlled, heavier children had a more significant chance of having elevated systolic blood pressure than normal-weight children, regardless of their race, height, or body mass index.

Adolescent↗

PubMed1990

Noninvasive assessment of cardiac output in children using impedance cardiography.

This study evaluated the effect of intracardiac shunting on the accuracy of thoracic bioimpedance-derived cardiac output determinations. Twenty-six patients, ranging in age from 3 months to 17 years, underwent cardiac catheterization during which simultaneous Fick and impedance measurements of cardiac output were obtained. The subjects were divided into three groups: 10 children with no intracardiac shunts, nine children with predominant left-to-right intracardiac shunts, and seven children with predominant right-to-left intracardiac shunts. Positive correlations between impedance and Fick-derived cardiac output determinations were obtained in the non-shunt group (r = 0.84), with lower correlations in the left-to-right shunt group (r = 0.70). In the right-to-left shunt group, the impedance derived cardiac output correlated with Fick pulmonary flow (r = 0.82), but the variability was unacceptably large. Although further study is needed, impedance cardiography appears to have validity as a methodology in pediatric critical care and cardiovascular health research.

Adolescent↗