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Biomedical subjects

F Aigner

Publications and source records attributed to F Aigner.

At least 37 records · Page 2Linked to original sources

[Value of preventive immunoglobulin administration in cadaveric kidney transplantation].

Transplant recipients have a high risk of infection, especially during the early postoperative period, due to impaired immune responsiveness. In a prospective randomized trial comprising 50 consecutive renal allograft recipients, a study was undertaken of the impact of prophylactic administration of immunoglobulins (Intragam) on the rate of infection. Similar numbers of infections were observed in both groups. They predominantly affected the lungs or the lower urinary tract. An unexpected result revealed by the study was that only 17 out of 25 patients of the immunoglobulin group, in comparison with 22 out of 25 of the control group were discharged with a functioning graft. It thus appears that the prophylactic administration of immunoglobulins to asymptomatic allograft recipients is not only useless, but probably also dangerous.

Adult

A safe technique for renal transplantation in patients with severely infected bladders.

A new surgical technique has been devised for the prevention of wound infection in cadaveric renal transplant recipients with severely infected bladders; the ascending colon is mobilized through a transperitoneal approach. The peritoneum covering the iliac vessels are retracted after blunt dissection, thereby forming a pouch. After completion of the vascular anastomoses, the ureter is brought into the peritoneal cavity through a small hole made in the peritoneum. The ascending colon is refixed to the abdominal wall so that the graft is separated from the bladder. No local or systemic infection occurred in two patients with purulent infection of the bladder who were operated upon with this technique.

Acute Disease

Our technique of combined renal and segmental pancreas transplantation.

This case, however, confirms our hypothesis that intraperitoneal positioning of a segmental pancreatic graft into the Douglas' pouch and an end to side arterial anastomosis bring several advantages as far as venous thrombosis and tryptic lesions are concerned.

Arteriovenous Shunt, Surgical

[Controlled results of standardized X-ray examination technique (author's transl)].

2000 patients were examined in our hospital within a period of 1 1/2 years using a standardized technique of x-ray examination of the stomach. Of these examinations, the gastroscopic, histological and partly also surgical results are now available from 241 patients. Hypotonic double-contrast technique, a highly dense, low-viscosity barium preparation and standardized documentation by means of 12 to 14 images taken with a 100 mm camera, have proved successful. The article reports on the accuracy of the x-ray examination based on these 241 results.

Clinical Trials as Topic

[Juvenile cadaver kidneys as suitable donor organs].

As several authors stated within the last few years and according to our experience as well cadaveric kidneys of young children are suitable for transplantation. Considering the shortage of transplantable organs en-bloc-transplantation should not be performed, even if this provides the opportunity to remove one kidney in case of surgical complications. On the other hand by transplanting a single organ one donor may help two recipients. Since it is known that kidneys of babies under 18 months do not guarantee sufficient function in adults, it should be a rule that kidneys of children under 18 months have to be transplanted en-bloc, whereas kidneys of older children can be transplanted solitarily without hesitation. Long term results with baby kidneys do in no way differ from kidneys of adults.

Adolescent

[Lymphocytic infiltrations in normal and pathological thyroid glands (so-called focal lymphocytic thyroiditis) (author's transl)].

A series of 1004 goitres removed surgically before (1959) and after (1970, 1975) the introduction of the iodine prophylaxis reveals an impressive increase in lymphocytic infiltration of the thyroid gland parenchyma. So-called focal lymphocytic thyroiditis is closely associated with the functional state of the organ. Furthermore, there is an increase in focal thyroiditis, especially in younger persons, after the introduction of iodine prophylaxis. Autoantibodies or clinical signs of inflammation were not found in these cases. Focal lymphocytic thyroiditis is seen as the expression of a regulatory function of the immunological system over the thyroid gland.

Autoantibodies