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Biomedical subjects

F Al-Sayegh

Publications and source records attributed to F Al-Sayegh.

2 recordsLinked to original sources

Rotavirus and non-bacterial infantile gastroenteritis in Kuwait.

The role of rotavirus in non-bacterial gastroenteritis in Kuwait was investigated. Employing electronmicroscopy (EM) and enzyme-linked-immuno-sorbent-assay (ELISA) techniques, the virus was detected in the stools of 42 of 274 (15.3%) infants with the disease. A statistically significant association (P less than 0.05) was found between virus excretion and age since 37 of 42 (88.1%) of rotavirus positive cases were aged 2-12 months. 57.1% of all rotaviruses detected were among specimens collected during the first 3 days since onset of clinical symptoms. In addition a highly significant relationship (P less than 0.01) was found between virus excretion and seasonal variation since highest virus excretion rates (76.1%) were detected in specimens collected during the autumn and early winter months, and coincided with the annual gastroenteritis season in Kuwait. Diarrhoea and vomiting were the most frequently encountered clinical symptoms being present in 92.9% and 76.2% of all rotavirus positive patients, respectively.

Age Factors↗

Laparoscopic splenectomy for hematological disorders.

OBJECTIVES: The aim of this prospective study was to evaluate the safety and feasibility of laparoscopic splenectomy (LS) in patients with hematological disorders of the spleen. SUBJECTS AND METHODS: Between 1999 and 2001, 15 patients (11 female and 4 male), with a mean age of 30 years, underwent LS after preoperative evaluation. If difficulties were encountered in LS, one trocar site incision was enlarged to 7-8 cm to engage the left hand for hand-assisted laparoscopic splenectomy (HALS) and the procedure was completed. Various parameters were reported, including spleen size as assessed by ultrasound scan, postoperative mortality and morbidity rates, accessory spleen removal, conversion rate, operative times and length of hospital stay. LS was successfully completed in 9 patients (60%) and HALS was performed in 4 patients (26.6%). Two patients required conversion to open splenectomy. RESULTS: The mean operative time was 209 min and the mean hospital stay was 8.1 days. The hospital stay was significantly longer among HALS patients than LS patients. The mean age of patients and splenic size were associated with a significantly higher conversion rate. No deaths were attributed to the procedure. Complications occurred in 2 of 15 patients. Accessory spleens were identified in 2 patients. CONCLUSIONS: LS is both a safe and feasible procedure, but it requires great technical care to avoid serious complications.

Adolescent↗