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Biomedical subjects

F Arbez-Gindre

Publications and source records attributed to F Arbez-Gindre.

23 records · Page 2Linked to original sources

[Latent pituitary adenoma. Autopsy study].

The incidence of latent pituitary microadenoma is poorly known as few studies have as yet been carried out. To address this problem, microadenoma was systematically looked for during 100 random routine post-mortem examinations in subjects with no endocrine disorders. Microadenoma was found in ten cases. Immunocytochemical study demonstrated prolactinoma in 6 cases, somatotropic adenoma in 1, mixed adenoma in 1, and non-functional adenoma in 2. Microadenoma seems more prevalent between fifty and sixty years of age. Outcome is discussed: spontaneous resolution, growth with onset of clinical manifestations, or persistence without changes in size.

Adenoma↗

[Deliberate poisoning with paraquat, death in less than 24 hours].

This paper describes a case of deliberate massive ingestion of Paraquat (over 300 mg/Kg). Evolution is toward a circulatory insufficiency with metabolic acidosis, hyperglycemia, and early death (18 hours). Severe pulmonary failure would have been expected, but not appeared. Autopsy revealed patchy necrosis of the liver but no severe damage of the other organs, including lung and adrenal.

Acidosis↗

[Results of colo-anal anastomosis].

Fifty five cases of rectal resection with colo-anal anastomosis are reported. There were 51 cases of cancer and 4 cases of large villous adenoma. The mean distance between tumor and anal verge was 6.4 +/- 1.1 cm (2-8). The mean resection margin was 29.1 +/- 14.6 mm (0-60). The resection was macroscopically complete in 45 cases of cancer distributed as follows: Dukes stage A = 14, stage B = 12 and stage C = 19. Nine (16.4%) postoperative complications occurred; among four (7.3%) anastomotic fistulas, three were treated by colostomy prolongation and one by abdomino-perineal resection. Thirteen (28.9%) recurrences occurred, of which three (6.7%) were local recurrences. The actuarial five years survival rates was 63%.

Adult↗