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F Argüelles Martín

Publications and source records attributed to F Argüelles Martín.

12 recordsLinked to original sources

[Utility of capsule endoscopy in pediatric gastroenterology].

Wireless endoscopy is a new noninvasive diagnostic method that is able to visualize small bowel lesions. The instrument is small and carries a battery and microcamera that takes two photographs per second. It is indicated in cases of bleeding of unknown origin and for the diagnosis of inflammatory bowel disease, among other disorders. To date, it has mainly been used in adults. We believe that this instrument could play an important role in the pediatric age group since it is noninvasive and can be used to diagnose small bowel lesions, thus avoiding unnecessary diagnostic tests. We report the case of a girl with suspicion of Crohn's disease that was unconfirmed by conventional endoscopic techniques. The capsule showed small bowel lesions compatible with Crohn's disease. Corticosteroid treatment was initiated and the patient is now in clinical remission.

Adolescent↗

[Familial aggregation in 91 families of hypercholesterolemic children].

OBJECTIVE: The aim of this study was to evaluate both the importance of the screening strategy and the familial aggregation characteristics of families with hypercholesterolemic children. PATIENTS AND METHODS: Ninety-one families (369 subjects) with one hypercholesterolemic child were studied. In addition to clinical and general biochemical evaluation, lipids including apo A-I and B-100 were examined. LDL was quantified under ultracentrifugation. RESULTS: Among the 91 children studied, 10 (10.99%) suffered heterozygous hypercholesterolemia, while 81 (89.01%) suffered polygenic hypercholesterolemia. Following a diet, polygenic children exhibited normal lipid parameters. In heterozygous children a decrease of 19% for total cholesterol, 19.9% for LDL-cholesterol and 16.3% for apo B were observed. When starting the study, 77.5% of the family members thought that they had normal serum lipid values. At the end of the study it was confirmed that only 28% were really normolipemic, indicating that 49.4% of the individual did not know that they were suffering dyslipemia. The study also showed that fathers exhibited the highest incidence of hypercholesterolemia (80.2%) followed by brothers (65.6%) and mothers (61.5%). Therefore, 69.4% of the individuals studied exhibited dyslipemia. CONCLUSIONS: The screening strategy allows one to diagnose a high percentage (almost 50%) of individuals suffering hypercholesterolemia in families with a child previously diagnosed of this pathology. Moreover, in these families there is a high degree of familiar aggregation of dyslipemia.

Adolescent↗

[The clinical manifestations of peptic esophagitis in children].

OBJECTIVE: To study the clinical spectrum of peptic esophagitis during childhood. PATIENTS AND METHODS: The clinical histories of 445 cases of peptic esophagitis, diagnosed by means of endoscopy or biopsy, in children between 1 month and 14 years of age were reviewed in order to analyze the reasons for endoscopy and the clinical symptoms presented. RESULTS: In the group under 2 years of age, the main symptom was vomiting, while in those between 2 and 6 years old it was also vomiting followed by abdominal pain. However, there was no significant difference between the groups. In the group over 6 years old, the chief complaint was abdominal pain with a statistically significant difference. CONCLUSIONS: 1) We found a statistically significant relationship between age and clinical data. 2) After comparing the grades of esophagitis with clinical symptoms and the age of the patient, no statistical correlation was found. 3) There is a high frequency of esophagitis I because of an early diagnosis.

Adolescent↗

[Diagnosis of gastroesophageal reflux: ultrasonographic method].

In this study, 63 infants, 38 males and 25 females, with pathology that suggested gastro-esophageal reflux, were studied. These patients were between one month and 7-1/2 years of age, with a mean age of 29 months and a standard deviation of 28.1 months. All patients underwent a barium study of the esophagus and the stomach, evaluated according to the criteria of Cleveland, an esophageal scintigram to detect GER, performed according to the criteria of Fernández and Argüelles, and an abdominal echography according to the technique of Naik and Moore. The test was considered a true positive if the echography was positive along with one other positive examination. A false positive was considered if only the echography were positive. A true negative was when the echography was negative along with another negative test. A false negative was when the echography was negative and some other test was positive. The following results were obtained for the echography: a sensitivity of 68%, a specificity of 84.61% and a safety factor of 71.2%. We conclude that echography can be considered as a complimentary examination for the study of GER, given it harmless nature, the availability of the equipment and the possibility of prolonging the exploration which can be recorded on videotape.

Child↗

[Xylose test. Anatomoclinical correlations].

We present a research work on the diagnosis of the malabsorption syndrome in childhood. The study is based on two diagnostic tests which are: the xylose test and the histological examination of intestinal mucosa. We have tried to assess the usefulness of the determination of the blood xylose after an extra oral load of xylose, comparing the results with the morphological findings in the intestinal mucosa, making a correlation between both, in order to discern the contribution of this examination to the diagnosis of the malabsorption syndrome in childhood. We come to the following conclusions: The determination of the blood xylose after an extra oral load with a single dose is a useful test in the diagnosis of malabsorption syndromes in childhood, and gives us facts about the status of the intestinal mucosa. The abnormality of the results of this test is an important indication for an intestinal biopsy. The xylose test cannot replace the intestinal biopsy.

Child↗