Biomedical subjects
F Atmetlla
Publications and source records attributed to F Atmetlla.
[Prethrombosis in child malnutrition].
Antithrombin III (AT III) and heparin antithrombin assay were estimated in 30 severely malnourished children and 40 normal children. The AT III was found significatively depressed and the heparin antithrombin assay showed a flat curve in the patients, which reflects a prethrombotic pattern in this group of children. Those findings agree with the high incidence of thrombosis reported in childhood malnutrition.
Antithrombin activities in childhood malnutrition.
Antithrombin activities in 30 severely malnourished children and 40 normal children were estimated in clotting tests by thrombin neutralisation as anti-Xa and by a heparin antithrombin assay; and by immunodiffusion as alpha 2-globulin and alpha 1-antitrypsin. The patients' mean alpha 2-globulin was severely depressed, and there were less marked depletions in mean values for thrombin neutralisation, anti-Xa, and in the heparin antithrombin assay (which showed the flat curve thought to reflect a thrombotic tendency). The alpha 1-antitrypsin values were normal. The findings support the concept of antithrombin as the summation of alpha 2-globulin and alpha 1-antitrypsin (with alpha 2-macroglobulin); and the low values may be related to the high incidence of thrombosis reported in childhood malnutrition, although it was not seen in these patients.
[Haemoglobinopathies and related disorders. II. Presentation of the proposed screening methods (author's transl)].
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Chemical characterization of a new haemoglobin variant haemoglobin J Cubujuqui (alpha2141(HC3)Arg replaced by Ser beta2).
Haemoglobin J Cubujuqui (alpha2141(HC3)Arg replaced by Ser beta2) was found during a screening for abnormal haemoglobins carried out in Costa Rica. This variant is clinically silent, although its substitution is in one of the residues involved in the stabilization of the deoxy form of the haemoglobin molecule.
[Disseminated intravascular coagulation as the first manifestation of gastric carcinoma (author's transl)].
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[Finding of haemoglobin E beta 26 (B 8) glu leads to lis in Costa Rica (author's transl)].
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A capillary test for the control of heparin therapy.
The BaSon test (Baden, Sonnenfield) for the control of heparin therapy has been studied in capillary and venous blood of normal and heparinized children and the same reliability is found. The sensitivity to heparin and the reproducibility of the test have been observed in in invitro studies and the findings show that the sensitivity is excellent and the reproducibility is very good.
[Comparison of methods for the control of therapy with heparin].
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