Biomedical subjects

F B Garry

Publications and source records attributed to F B Garry.

39 records · Page 3Linked to original sources

PubMedDate not supplied

Naturally occurring acute coliform mastitis in Holstein cattle.

Physical examination and clinicopathologic findings from 44 adult Holstein cows with naturally occurring coliform mastitis were studied. The cattle were grouped for comparison by stage of lactation and survival. Cattle within the first 4 weeks of lactation maintained higher median mature neutrophil counts (1,200 versus 300/microL) in peripheral blood than cattle later in lactation. Nonsurviving cows had higher median creatinine concentration (2.5 versus 1.6 mg/dL) and anion gap (25 versus 20 mEq/L), and lower serum protein (7.1 versus 7.6 gm/dL) and total CO2 (19.8 versus 25 mEq/L) concentrations than surviving cows (P < .05). These findings indicate that cattle with uremia and metabolic acidosis are less likely to survive the infection. Bacteriologic blood cultures were performed on 34 of the 44 cows studied. Escherichia coli was isolated from the blood in 11 (32%) cows. Clinical presentation and clinicopathologic data were compared in bacteremic versus nonbacteremic cows to evaluate these data as predictors of bacteremia. Bacteremic cows were sick longer prior to admission (2 versus 1 days), maintained higher median counts of total nucleated cells (6.6 versus 2.4 x 10(3) cells/microL), myelocytes (0.2 versus 0 x 10(3) cells/microL), metamyelocytes (0.5 versus 0.02 x 10(3) cells/microL), band neutrophils (0.7 versus 0.1 x 10(3) cells/microL), and lymphocytes (2.1 versus 1.4 x 10(3) cells/microL) than nonbacteremic cows, and had higher plasma fibrinogen concentration (600 versus 500 mg/dL) (P < .05). There were no differences between the physical or serum biochemical measurements. Four of 11 bacteremic cows and 5 of 23 nonbacteremic cows died or were euthanized (P > .05). The high prevalence of bacteremia seen in cows with coliform mastitis has not been reported previously, and may have been due to the duration of disease, severity of signs, or culture technique. These findings suggest that systemic antibiotic therapy may be beneficial in some severe cases of coliform mastitis.

Animals↗

PubMedDate not supplied

Hepatic lipidosis in anorectic, lactating holstein cattle: a retrospective study of serum biochemical abnormalities.

The association between hepatic lipidosis (HL) and disease in 59 anorectic, ketotic, lactating Holstein heifers and cows was investigated. Severe HL, as determined by histologic evaluation of liver tissue, was present in 46 animals; only half of these animals required intensive treatment for ketosis, and only half had serum biochemical evidence of liver disease, as determined by the presence of a last value of 2-fold or greater than the upper limit of the reference ranges for at least 2 of the 4 serum tests: gamma-glutamyl transferase, aspartate aminotransferase, and sorbitol dehydrogenase activities and bile acid concentrations. Most cattle with biochemical evidence of liver disease and severe HL had been lactating for 14 or more days. Cows that required intensive treatment inconsistently had serum biochemical evidence of liver disease. Although cattle with severe HL had significantly higher serum bilirubin concentrations and aspartate aminotransferase and sorbitol dehydrogenase activities than cattle with less severe lipidosis, the specificity of abnormally high serum sorbitol dehydrogenase activity or bilirubin concentration for severe lipidosis was only 8%. Abnormally high serum aspartate aminotransferase activity was 83% sensitive and 62% specific for severe lipidosis. Serum glucose and total carbon dioxide concentrations were significantly lower in cattle with severe lipidosis than in those with mild or moderate lipidosis, and low serum glucose or total carbon dioxide concentrations were rare in cattle without severe lipidosis. From these data, we conclude that the use of a single biochemical or histopathologic criterion to define severity of disease or degree of liver compromise in anorectic, ketotic cows results in the misidentification of many animals.

Animals↗

PubMedDate not supplied

Treatment of neonatal calf diarrhea with an oral electrolyte solution supplemented with psyllium mucilloid.

Dairy calves under 14 days of age with naturally occurring, uncomplicated diarrhea were treated for 3 days with a hypertonic oral electrolyte solution with (n = 15) or without (n = 12) psyllium. Clinical response and clinical pathology data were compared between the 2 groups. Glucose absorption was evaluated on days 1 and 3 by measurement of plasma glucose and lactate and serum insulin concentrations for 4 hours after formula administration. On day 1, glucose, lactate, and insulin concentrations were lower in psyllium-fed calves than in control calves, with significant differences noted in glucose and lactate concentrations at several time points (P < 0.05). Plasma lactate concentrations were higher at several times in both treatment groups on day 3 than on day 1 (P < 0.05). Fecal consistency was markedly different in psyllium-fed calves as compared with control calves within 24 hours of psyllium supplementation. Fecal percent dry matter content was lower in psyllium-fed calves than in control calves at least once a day during supplementation and on day 3 compared with day 0 in the psyllium-fed calves (P < 0.05). There were no significant differences in clinical performance scores, hydration status, arterial blood gas, serum anion gap, electrolyte, or total CO2 concentrations. Addition of psyllium to an oral electrolyte solution resulted in immediate alterations in glucose absorption without impairing rehydration in diarrheic calves, but differences were transient and did not affect clinical outcome.

Absorption↗