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Biomedical subjects

F B Gibberd

Publications and source records attributed to F B Gibberd.

At least 55 records · Page 3Linked to original sources
PubMed1982

The clinical accountable team.

This paper examines an experiment in an unusual method of accounting and budgeting, and discusses its implications to clinicians. Clinical teams were made responsible for their own expenditure. They were supplied with a breakdown of their expenditure and a budget based on previous expenditure. Each team, at its own discretion, could use savings made from reducing expenditure in one sphere to provide unrelated services. Reduced expenditure was achieved and new projects started.

Accounting↗
PubMed1981

The influence of folic acid on the frequency of epileptic attacks.

A double blind trial of folic acid against placebo was carried out on out-patients with epilepsy treated with Phenytoin. There was a minimum period on treatment of one year. While the group receiving folic acid in the treatment period showed a significant improvement in seizure frequency, the placebo group also showed some improvement. It is concluded that the improvement while on folic acid was not due to the folic acid treatment alone. The subjective well-being of patients was not influenced by folic acid therapy.

Adult↗
PubMed1980

Neurological disease in ex-Far-East prisoners of war.

In a group of 4684 ex-Far-East prisoners of war released in 1945, 679 had neurological disease; optic atrophy and peripheral neuropathy were the most common illnesses. However, in 89 patients neurological disease developed many years after their release; 35 of these patients had cord lesions unlike those seen in multiple sclerosis and other recognised diseases. In addition, Parkinson's disease often developed many years after release with a prevalence much higher than that in the normal population. The experiences that these patients had while in the Far East may have made them liable to develop cord disease and Parkinson's disease many years later.

Adult↗
PubMed1980

Epilepsy and other factors in the prognosis of gliomas.

A study of 95 patients with gliomas has been made. The 50% survival was 15 months after the first symptom. At the time of presentation all patients had an abnormal brain scan and E.E.G. except some of those who presented with epilepsy. The patients with epilepsy had a significantly better prognosis than those without and this was not due to their having less malignant tumours according to histological appearance. Other factors which were associated with significantly longer survival were a younger age at presentation, partial removal of the tumour rather than biopsy or no operation, lower histological grades of tumour and treatment with radiotherapy or chemotherapy.

Adult↗
PubMed1980

Heredopathia atactica polyneuritiformis (Refsum's disease): 1. Clinical features and dietary management.

In a patient with Refsum's disease successful dietary control of the disease has been shown to depend on adequate energy and protein intake from phytanic acid-free sources and restriction of dietary phytanic acid to a maximum of 10 mg per day, with the provision of a generous amount of the essential fatty acid, linoleic acid. The present work gives data on the phytanic-acid content of various foodstuffs and suggests dietary manipulation of the patient. Although the role that chlorophyll-bound phytol plays in Refsum's disease is uncertain, it is advisable that this is eliminated until its role is more clearly identified.

Adipose Tissue↗
PubMed1976

Incidence of deep vein thrombosis and leg oedema in patients with strokes.

In a series of 26 patients with strokes 13 had deep vein thrombosis (DVT) in the leg, demonstrated by fibrinogen scanning. In 10 patients the thrombosis was in the paralysed leg but the degree of paralysis was unrelated to the tendency to develop DVT, which usually occurred about the third day. Leg oedema in 10 patients was unrelated to the DVT.

Cerebrovascular Disorders↗
PubMed1976

Who is epileptic?

Explore the source record for details and available documents.

Electroencephalography↗
PubMed1975

Studies in man of phenytoin absorption and its implications.

The absorption of phenytoin was studied in man. It is concluded that phenytoin absorbed from the intestine is recirculated via the bile, so that blood levels do not accurately reflect absorption. Phenytoin is loosely bound to serum proteins and is found in red cells in concentrations similar to those in plasma. It is rapidly lost from the blood stream after intravenous administration, which is an important factor to be considered in the treatment of status epilepticus.

Administration, Oral↗
PubMed1974

Sleep epilepsy: its pattern and prognosis.

In a series of 645 patients with epilepsy only 38 had attacks exclusively during sleep. A further 111 had attacks while waking and sleeping. The total number of patients whose epilepsy started with sleep attacks and who later developed attacks when waking increased with each successive year. The prognosis of sleep epilepsy is important in relation to the granting of driving licences.

Adult↗
PubMed1974

Oesophageal dilatation in Parkinson's disease.

In an unselected group of 37 patients with Parkinsonism the mean diameter of the oesophagus at the level of the 9th dorsal vertebra was 3·11 cm, which was significantly higher than the mean of 2·24 cm in a group of control patients. Six of the patients with Parkinsonism had gross oesophageal dilatation.

Dilatation↗
PubMed1973

Interaction between levodopa and methyldopa.

The interaction between methyldopa and levodopa was studied in 18 patients with Parkinsonism. Together they produced a fall in blood pressure in doses which when given alone had no effect or only a slight hypotensive effect. Severe hypotension never occurred. It is reasonable to give methyldopa to hypertensive patients on levodopa but the regimen should be initiated in hospital.

Blood Pressure↗