Intraoperative electron beam therapy for unresectable cancer of the pancreas.
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Biomedical subjects
Publications and source records attributed to F Bagne.
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The design and construction of a mesh panel for radiation therapy treatment tables is described. With the new design, sagging is virtually eliminated. The panels have been successfully used for a variety of patient sizes and weights.
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Effects of beam quality, cavity size, TLD state, and medium on the response of thermoluminescent dosimeters were studied. LiF TL-700 powder, extruded rods, and ribbons were irradiated with Co-60 gamma rays, 4, 6, 8, 33, and 45 -MV x rays, and 3, 5, 10, 15, 20, 25, 30, 35, 40, and 45-MeV electrons. Relative TL responses were assessed in water and Lucite, and the results compared. The results of this study were compared with those of previously published studies, and certain discrepancies resolved.
A practical method for routine patient dose monitoring when single, multiple, or adjacent fields are irradiated with supervoltage x rays is described. The system uses litium fluoride TL-700 extruded rods in small gelatin capsules. The mode of calculation is described and the experimental data for 33- and 45-MeV energy betatron x rays are presented. An example is given to illustrate the use of this technique (experimental uncertainty, 3%).
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Some of the physical parameters necessary in electron beam treatment planning are investigated for 5- to 45-MeV electrons extracted from a Brown-Boveri betatron. The percent depth ionization (PDI) curves are compared with the empirical relation given by Laughlin's equation, and an extension of Laughlin's equation is described. The modified absorption coefficient (MAC) method is introduced to correct the isodose distributions for the presence of inhomogeneities, such as lung, with the actual density of lung and the location of the inhomogeneity taken into consideration. Experimental data from measurements made in a water-cork phantom are presented, and the results are compared with the various calculated methods.
This work considers the problems associated in megavoltage x-ray dosimetry concepts with the current techniques used for normalizing the various dose parameters. The depth of transient charged particle equilibrium (CPE) is introduced as the optimum choice of the normalization point. Properties of this depth are discussed and its uniqueness as a measure of beam quality is illustrated.
Limitations of the most commonly used dose calculation methodologies as apply to medium and high-energy x rays are discussed. A method is presented whereby the dose to a point in medium is divided into several components with expressions given for various components. The depth of transient-charged particle equilibrium is chosen as the reference point. Equations are derived for calculating and relating the dose parameters including the percent depth dose, the tissue-reference ratio, and the scatter-reference ratio. Particular emphasis is placed on the accuracy and adequacy of the technique in the region of buildup. The applicability of the present method to megavoltage photons is established for a number of x-ray beams in the range 4-45 MeV maximum energy.