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Biomedical subjects

F Bandello

Publications and source records attributed to F Bandello.

At least 55 records · Page 3Linked to original sources
PubMed1993

Cystoid macular oedema after extracapsular cataract extraction and intraocular lens implantation in diabetic patients without retinopathy.

Postoperative onset or aggravation of cystoid macular oedema (CMO) in diabetic patients after extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation is a frequent problem. At present little is known about the occurrence and prognosis of this complication in diabetics with no clinically detectable diabetic retinopathy (DR). Twenty five diabetic eyes (24 subjects) without DR and 45 normal eyes (44 subjects) were studied before surgery and 30, 90, 180, 360 days after ECCE and posterior chamber IOL implantation. Fluorescein angiography was performed at each examination. The frequency of angiographic CMO in the two groups was comparable 30 days after surgery but was significantly higher in diabetic eyes at 90, 180, and 360 days. This finding is probably related to an impairment of the blood-retinal barrier in diabetics. Final visual acuity, however, was similar in the two groups.

Aged↗
PubMed1993

Laser treatment of iris vascular tufts.

We describe a case of iris vascular tufts which came to our attention because of a hyphaema. Laser treatment was carried out for the vascular anomalies. After a period of 3 months, fresh vascular anomalies had appeared in different locations. Further treatment led to permanent obliteration. We emphasize the importance of fluoro-iridography in the monitoring of vascular anomalies as it allows accurate targeting treatment.

Female↗
PubMed1991

Diabetic retinopathy after successful kidney-pancreas allotransplantation: a survey of 18 patients.

To investigate the effects of normoglycaemia on diabetic retinopathy, we evaluated 18 uremic diabetic patients before and after successful pancreas kidney transplantation. In all, 12 uremic diabetic patients who submitted to kidney transplantation alone served as the control group; 4 of these subjects received a kidney transplantation alone, whereas 8 underwent a double kidney-pancreas transplantation but lost the pancreas graft within the first few weeks post-surgery. The mean age and the mean duration of both diabetes and dialysis were comparable in the two groups. All patients were studied prior to and at 6 and 9 months after surgery, then at annual intervals. Subjects were divided into three groups according to follow-up: less than 1 year, between 1 and 3 years and greater than 3 years. At each control visit, a complete clinical examination was performed by two independent examinators; retinal fluorescein angiography was carried out as well. The following parameters were evaluated: visual acuity, capillary closure, macular oedema, neovascularization at the disk and elsewhere and vitreous haemorrhage. A score ranging from -2 to +2 was assigned to each parameter for quantification of the variation between baseline values and those obtained at the end of the follow-up. This score was assigned by two different ophthalmologists. Eyes that were affected at baseline by end-stage diabetic retinopathy (secondary retinal detachment, neovascular glaucoma) were not entered in the study. A total of 18 eyes were lost to follow-up in the 2 groups because of laser treatment, cataract extraction, anterior ischaemic optic neuropathy and cytomegalovirus retinitis.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

Effect of pancreas transplantation on diabetic retinopathy: a 20-case report.

In order to study the effects of normoglycaemia on diabetic retinopathy, 20 diabetic uraemic patients who underwent a kidney-pancreas transplantation were evaluated before and after surgery (6.9 months and once a year). The control group consisted of 12 uraemic patients who underwent kidney transplantation alone. At each follow-up examination a complete clinical examination and a retinal fluorescein angiography were performed. The eyes with end-stage retinopathy at baseline were excluded from the study. The analysis of the results showed no significant differences in the two groups. The diabetic retinopathy at the moment of the transplantation was already too advanced to benefit from the better glycaemic control.

Adult↗
PubMed1991

New laser modalities for posterior segment treatment.

Laser light is currently used for photocoagulation and photoresection in the posterior segment of the eye. Randomized controlled clinical trials on huge caselists, employing rigorous methodology, have confirmed the efficacy of photocoagulation treatments in numerous retinal pathologies. On the basis of the findings of these trials, precise treatment protocols have been drawn up. Nevertheless, some doubts persist on the indications and exact modalities for laser treatment in certain clinical forms. While the various treatment protocols were being defined, research was focusing on the development of new equipment that would maintain at least the same level of therapeutic efficacy as conventional apparatus while offering advantages in reliability, costs, ease of handling, and working life. An important product of this line of research is the semiconductor diode laser photocoagulator. The new frequency-doubled neodymium:yttrium-aluminum-garnet laser and the continuous wave neodymium:yttrium-aluminum-garnet laser hold promise for contact photocoagulation. Photoresection is acknowledged now as an important means of dealing with vitreoretinal lesions. It provides an adequate solution in selected cases of vitreoretinal pathology and serves as a useful adjunct in conventional surgery.

Choroid Diseases↗
PubMed1991

[Central serous retinopathy (atypical forms)].

In comparison with the typical forms of the central serous chorioretinopathy (CSCR), atypical forms are characterized by an older age, the presence of multiple and bilateral foci, the higher tendency for recurrence and the more accentuated functional damages. They may take the form of DRPE (diffuse retinal pigment epitheliopathy) and of gravitational epitheliopathy. Sedative therapy is justified by the particular psychic background which often accompanies this disease. Photocoagulation must be performed only in very selected cases in order to reduce the damage at the level of the macular photoreceptors.

Adult↗
PubMed1990

[Medical treatment of diabetic retinopathy].

The pathogenesis of diabetic retinopathy (DR) consists of a complex patch-work of factors correlated and independent on one another at the same time. It is therefore difficult to find pharmaceuticals able to produce different, or even mutually contrasting effects. Another difficulty are the intrinsic characteristics of the disease which after developing to a "critical" stage, evolves with independent mechanism to the most advanced stages. In spite of that, a great deal of medicaments has been suggested so far, all providing therapeutical logic to interfere with one or more pathogenetical stages of the lesions. Although several clinical trials have been performed, survey and follow-up are still limited and insufficient to draw conclusion on the effectiveness of medical therapy. In recent times new types of medicaments such as aldose-reductase inhibitors and carbonic anhydrase-inhibitors have been suggested. The preliminary results present encouraging perspectives for their use, although caution, until long-term results are available with greater surveys and longer follow-up periods, is advised.

Diabetic Retinopathy↗
PubMed1989

Normal exophthalmometric values in children.

We used a Hertel exophthalmometer to measure the degree of ocular protrusion in 852 subjects who had no history of orbital trauma or disease, endocrine disease, severe myopia, buphthalmos, or craniofacial deformities. The subjects ranged in age from 3 to 10 years. No statistically significant difference was observed between boys and girls or between right and left eyes in each age group. The mean normal protrusion values ranged from 9.11 mm in the 3-year-old group to 11.67 mm in the 10-year-old group. The mean outer orbital margin distance ranged from 78.7 mm in the 3-year-old group to 89.1 mm in the 10-year-old group. The data obtained were tabulated to plot percentile distribution curves of normal exophthalmometric values and outer orbital margin distance in children. No subject had more than 2 mm of asymmetry between the eyes.

Age Factors↗
PubMed1989

Prevalence of retinopathy in diabetic subjects from out-patient clinics in Lombardy (Italy), and associated risk factors. A multicentre epidemiologic study.

There is little information on the prevalence of diabetic complications in Italy. For this reason, a multicentre population-based study was carried out in 1983-1985 in 12 representative out-patient clinics for the treatment of diabetes in the Lombardy region. Out of a total population of 17,704 patients 1160 diabetic subjects were randomly selected within strata based on their duration of disease (less than or equal to 5; 6-10; 11-20; greater than 20 years). Eight hundred and thirty-eight responders were examined using standardised protocols. The estimated prevalences (adjusted for duration of disease) for the total population involved in the study were 29.7% and 7.6% for background and proliferative retinopathy respectively. The overall standardised rates were higher in insulin-dependent diabetes mellitus (IDDM) (53.6%) than in non-insulin-dependent diabetes mellitus (NIDDM) (34.7%) for both background (41.1%, 28.4% respectively) and proliferative (12.5%, 6.2% respectively) retinopathy, and increased with the duration of disease. The analysis of the relationship between diabetic retinopathy and the calculated risk factors did not show any association with hypertension or metabolic control, except for post-prandial blood glucose in subjects with durations 6-10 and greater than 20 years; an association with azotaemia was found in subjects with durations less than or equal to 5 and 11-20 years. Diabetic retinopathy appeared to be independently associated with the type of treatment and not with the type of diabetes, metabolic control, or hypertension.

Diabetic Retinopathy↗
PubMed1988

[Fluoroiridographic aspects of iridoschisis].

Iridoschisis is a rare condition of uncertain etiology characterized by a cleavage of the iris layers. We report four cases studied by fluorescein angiography to display possible occurrence of vascular abnormalities in the pathogenesis of the disease. Case 1: 80 year old woman with bilateral schisis of the peripheral iris, in the inferonasal quadrant in RE and inferotemporal in LE. A shallow anterior chamber was present in OU; IOP was 18 in RE and 15 in LE. No corneal abnormalities were present. Fluoroiridography showed a normal pattern filling of the iris vascularity, that was more visible in the schisis area. Case 2: 66 year old man with diabetes and open-angle glaucoma operated on for trabeculectomy five years previously. The examination showed a normal cornea, a shallow anterior chamber and miotic pupils for pilocarpine therapy. IOP was 12 in OU. The iridoschisis was present in RE in the lower sectors which were totally involved from the outer iris to the inner pupillary margin. Fluoroiridography indicated a normal vessel perfusion without any abnormality in the affected sectors. A slight bilateral pupillary dye leakage without any stromal diffusion was attributable to the patient's age. Case 3: 55 year old woman treated with miotics in RE for a glaucoma diagnosed after head trauma twenty years before, after which the vision in LE was reduced to 2/200 for post-traumatic optic nerve atrophy. No corneal abnormality was present. The anterior chamber was shallow and the ocular tension was 14 in RE and 10 in LE.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1987

Proliferative retinopathy and toxemia of pregnancy.

Retinopathy occurring during toxemia of pregnancy generally shows the features of hypertensive retinopathy. The authors describe the case of a patient with bilateral peripheral neovascularizations following toxemia of pregnancy. The likely pathogenesis is ascribed to the development of ischemic areas, which can be determined by microthrombus formation. Presently, low-grade disseminated intravascular coagulation is considered very important in the pathogenesis of toxemia of pregnancy. After panretinal fluorangiography, a selective photocoagulation of ischemic areas was performed. The regression of neovascularizations was observed after one month. No similar case report could be found in the literature.

Adult↗
PubMedDate not supplied

Ultrasound biomicroscopy following the intraocular use of silicone oil.

We evaluated the ultrasound biomicroscopy findings and the amount and location of silicone oil residue in anterior structures of the eye before and after silicone oil removal. We examined the anterior structures in 40 silicone oil 1000 cs-filled eyes at the end of silicone oil tamponade time (mean silicone oil tamponade duration 5.1 months), and in the same eyes after silicone oil removal. High resolution ultrasound biomicroscopy, 50 MHz transducer, 50 microns of resolution, was used. Silicone oil droplets--often not ophthalmoscopically visible--appeared as highly reflective images with after ringing effect. They were present in the anterior structures of the eye in up to 95% of eyes with silicone oil in the vitreous cavity, and in up to 87.5% after careful silicone oil removal. With ultrasound biomicroscopy it was possible to identify small silicone oil droplets with a typical morphological appearance. Once silicone oil is used in vitreoretinal surgery, its complete removal from the anterior structures of the eye is very difficult to achieve later on.

Adolescent↗
PubMedDate not supplied

Updating on intraoperative light-induced retinal injury.

We are presenting the state of knowledge concerning intraoperative light-induced retinal injury, considered to be a combination of photic retinopathy and retinal photocoagulation. It may arise from retinal light exposure to the operating microscope or to the fiberoptic endoilluminator. Ultraviolet and short-wavelength visible light are more dangerous than longer wavelength light. Many risk factors may facilitate the onset of this iatrogenic disease following surgery. Many aspects of the retinal damage are still poorly understood. Many mid light-induced retinal injuries probably remain undiagnosed in routine postoperative examination. Current appropriate light filters are not the definitive solution. Appropriate precautions should be taken during both anterior segment and vitreoretinal surgery.

Aged↗