Cariology, Zurich 1953-1983. Some aspects of one man's stand.
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Biomedical subjects
Publications and source records attributed to F Barbakow.
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The fluoride retention in enamel was determined in vivo comparing the short-term unsupervised use of amine fluoride- and monofluorophosphate-sodium fluoride-dentifrices. Acid-etch enamel biopsies in the double-blind study showed that the fluoride content in enamel was significantly higher following use of the amine fluoride dentifrice, 959 ppm F vs 330 ppm F. Both dissolution of the enamel, determined by the amount of phosphorus (33.9 micrograms vs 50.9 micrograms) and the depth of etch (6.2 microns vs 9.6 microns) were significantly reduced after use of the amine fluoride compared to the monofluorophosphate-sodium fluoride combination.
Zinc in combination with hexetidine has been shown to be an effective chemical antiplaque agent clinically and in the laboratory. The effects of zinc fluoride on ground human enamel were studied by SEM and the sizes and numbers of the resulting globular structures measured from photomicrographs. Prepared enamel specimens were immersed in zinc fluoride solutions containing 250 and 750 ppm F- at pH 6 and 4 for 4 min. The specimens were examined as such or after washing in water for 5 min, 60 min or 24 h and the globuli categorized as larger or smaller than 0.5 um. The sizes and numbers of the globuli on the enamel were pH and concentration dependent. At pH 6, the two solutions tested produced few small globuli on enamel which were removed after 5 min (250 ppm F-) and after 60 min (750 ppm F-) in water. At pH 4, markedly more globuli were present, particularly with the 750 ppm F- solution. Large and small globuli were present after the 250 ppm F- treatment with most being removed between 5 and 60 min in water. After the 750 ppm F- treatment only small globuli were found on enamel and were removed between 60 min and 24 h of water washing. Zinc fluoride-induced globuli were generally smaller than those induced by sodium fluoride at the same pH values and fluoride concentrations.
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