Biomedical subjects
Publications and source records attributed to F Barduagni.
A case of ossifying fasciitis in a 22-year-old woman is described. The lesion, which appeared suddenly, was located on the tip of the nose. Histologically the lesion contained spindle-shaped myofibroblastic cells, trabeculae of woven bone rimmed by plump osteoblasts within a myxoid stroma.
After a short review of the literature, starting from the last decades of the past century, the current classification of the Dirofilaria genus is shown with its two subgenera: D. immitis and D. nochtiella (repens, tenuis and ursi). The first case of subcutaneous and pulmonary dirofilariasis caused in Italy by D. repens is then shown as well as a research on dog populations in which D. immitis is prevalent. The fact that D. immitis has not yet been isolated in humans, in Italy, is probably due to D. repens vectors being more anthropophile. Finally, the latest cases of dirofilariasis from D. repens reported in Italy are taken into consideration along with the one isolated by the Authors, complete with illustrations. The case presented has been diagnosed on the basis of the histological examination carried out on a soft nodule detected in the right pectoral region; furthermore, eosinophilia and an elevated value PRIST were present.
Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English literature to date. A healthy 32-year-old woman is reported, with approximately 400 asymptomatic rounded papules, on the upper and lower extremities. Multiple skin biopsies showed the typical histological pictures of CCA. This case appears unusual because of the presence of numerous lesions scattered on the upper and lower extremities. For this reason it could be classified as disseminated eruptive CCA.
A 39-year-old woman is reported who developed numerous confluent yellowish semitranslucent papules of the face over 8 months. The patient habitually exposed herself to UVA-radiation twice a week for 7 years for aesthetic reasons. Histological, histochemical and immunohistochemical examinations were consistent with the diagnosis of adult colloid milium. A review of the literature is discussed. This case emphasizes the close relationship between long-term sun exposure, solar elastosis and adult colloid milium.