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F Bartlett

Publications and source records attributed to F Bartlett.

7 recordsLinked to original sources
PubMed1978

Evoked response correlate of symbol and significate.

Changing the source and intensity of the auditory signal to six trained cats responding to meaningful auditory stimuli permits exogenous and endogenous processes in the auditory evoked potential to be separated. For short-latency exogenous processes, latency and amplitude depend on the parameters of the physical stimulus. However, the amplitude and shape of longer-latency endogenous processes are essentially independent of the location and intensity of the signal source and seem to be invariant concomitants of the significance of the signal.

Animals↗
PubMed1977

Neurometrics.

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Aged↗
PubMed1977

Disposition of pirprofen, a new anti-inflammatory drug.

Plasma and urine concentrations of 2-(3-chloro-4[3-pyrrolinyl]phenyl) propionic acid, pirprofen, a new nonsteroidal anti-inflammatory compound, are described for normal male volunteers receiving one or more doses of the drug. Orally administered pirprofen is rapidly and almost completely absorbed from the gastrointestinal tract, resulting in maximum plasma levels in 1 to 2 hr. Mean peak levels are 23 microng/ml after an oral pirprofen dose of 200 mg; lower doses given proportionally lower levels. Administration 1 hr after a meal slightly delays the peak plasma level, but the extent of absorption is not affected significantly. Administration of pirprofen, 150 mg, 4 times daily, or 200 mg, 3 times daily, results in nearly identical plasma levels at steady-state. Pirprofen has an apparent elimination half-life of about 7 hr. The results obtained from a 200-mg pirprofen-14C dose indicate that excretion of the drug occurs primarily by the renal route in the form of metabolites and is essentially complete within 24 hr. In urine, less than 5% of the administered dose is accounted for as unchanged drug.

Adolescent↗
PubMed1973

Equipotentiality quantified: the anatomical distribution of the engram.

Sensory events and the representation of past experience cause distinctive changes in the electrical activity of widespread regions of the brain. These regions have similar roles in the engram in the sense that they all seem to participate in responses to external events and in subsequent representations of these events. However, the relative contribution of these processes to the activity of different brain regions is quantitatively different, in that some regions are much more strongly affected than others. These results may constitute the basis for reconciliation of localizationist and antilocalizationist views of brain function.

Animals↗