[Continuing medical education in the United States].
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Biomedical subjects
Publications and source records attributed to F Baumann.
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Validity and efficiency of an antibiotic prophylaxis after extensive orthopedic and traumatological procedures are not universally accepted. Often the systematic antibiotic prophylaxis is withhold because of considerable disadvantages. A new method is reported, which enables a bactericidal antibiotic therapy based on bacteriological testing of swabs taken during and after surgery. Thus the administration of antibiotics is possible long before the clinical manifestation of an infection. Immediate therapy diminishes the danger of complications from infections. With this method microbial contamination was found and treated in 53 (17.44%) of 305 operations. Of these, only 0.66% resulted in deep infections and 3.6% delayed healings without further complications.
The paper introduces a new method for limb lengthening using an extension nail. Animal and clinical results are encouraging. Further clinical results and long term observations will be presented soon.
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One case of osteochondrosis dissecans of the carpal scaphoid is reported. The diagnosis is built upon clinical, radiographical, intraoperative and histological statements. Concerning the aetiology there exists as well a dysplay on the scaphoid on the other side. It might be caused by overcharging of the wrist.
Blood pressure measurements (Phyiometrics SR1) were performed on 21 589 persons visiting the Swiss Trade Fair in Basel in 1974. Diastolic pressures were found to be greater than or equal 110 mm Hg in 3%, greater than or equal 100 mm Hg in 7% and greater than or equal 95 mm Hg in 12% of the screened population. Including those under antihypertensive treatment, the prevalence of high blood pressure (diastolic pressure greater than or equal 95 mm Hg) amounted to 19% of the adult population. In 68% of the hypertensive screenees the condition was already known, 49% were under treatment and 35% were controlled (i.e. diastolic pressure less than 95 mm Hg). In other words - and here lies the unsolved problem - 32% of hypertensives are as yet undetected, 19% of the known cases are not treated, and 14% are inadequately treated. Of the hypertensive population 35% are adequately treated and 30% have mild hypertension. The remaining 35%, with diastolic pressure greater than or equal 100 mm Hg, require urgent attention and action. In Switzerland this problem can be tackled and solved by the general practitioner, who already play the major role in detection and treatment.
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In the honey bee drone, the decrease in sensitivity to light of a retinula cell exposed to background illumination was found to be accurately reflected by the difference in amplitude between the initial transient depolarization and the lowest steady depolarization evoked by the background light. It is shown that both the decrease in sensitivity to light and the accompanying drop in potential from the transient to the plateau can be prevented by injecting EGTA intracellularly. A decrease in duration and amplitude of responses to short test flashes such as observed immediately after illumination was found to occur too when Ca or Na, but not K, Li, or Mg injected into dark-adapted retinula cells. Injection of EGTA into a retinula cell maintained a steady state of light adaptation, was found to cause an increase in amplitude and duration of the response to a short test flash, thus producing the effects of dark adaptation. It is suggested that, in the retina of the honey bee drone, an increase in intracellular calcium concentration plays a central role in light adaptation and that an increase in intracellular sodium concentration, resulting from the influx of sodium ions during the responses to light, could lead to this increase in intracellular free calcium.
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